Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Fuerte Amador Resort & Marina

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Visit the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

Learn about the local history of Ancon when you spend time at Miraflores Locks. Visit the casinos and shops in this vibrant area.

Miraflores Locks
Calle 50

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.

Calle 50

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

HK$942
per adult
80% of travellers recommend
Slingshot Tour Panama
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

HK$1,170
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
Panama City Visit an Indian town Embera and waterfall with lunch

Panama City Visit an Indian town Embera and waterfall with lunch

HK$392
per adult
96% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

HK$252
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
Panama City Tour and Panama Canal – Miraflores Locks Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

HK$275
per adult
98% of travellers recommend
Panama City Tour and Panama Canal – Miraflores Locks Experience
The Panama Barcrawl - The OG Crawl

The Panama Barcrawl - The OG Crawl

HK$510
per adult
96% of travellers recommend
The Panama Barcrawl - The OG Crawl
See all activities in Panama City

Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
Stay at this 3-star condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera are ...
9.2/10 Wonderful! (45 reviews)
"Excellent location and great food."

Reviewed on 25 Aug 2025

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Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is HK$853 per night from 27 Aug to 28 Aug
HK$853
HK$938 total
27 Aug - 28 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,194 reviews)
Great stay
"This hotel gave me one of the most luxurious hotel experiences I’ve ever had. It is centrally located with easy access to all your daily social and business needs. The room was brilliantly designed to ensure for the customer luxury feel, comfort, convenience, and ample space. The staff were very ..."

Reviewed on 23 Aug 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is HK$1,695 per night from 8 Sept to 9 Sept
HK$1,695
HK$1,695 total
8 Sept - 9 Sept
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.2/10 Good! (1,007 reviews)
"Great"

Reviewed on 23 Aug 2025

Dreams Playa Bonita Panama - All Inclusive
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
The price is HK$633 per night from 2 Sept to 3 Sept
HK$633
HK$696 total
2 Sept - 3 Sept
includes taxes & fees
Stay at this 4-star spa B&B in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Via Espana are located ...
9/10 Wonderful! (430 reviews)
"Definitely an amazing hotel !! I will be back !!!"

Reviewed on 23 Aug 2025

Waymore Hotel Spa & Casino
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is HK$891 per night from 11 Sept to 12 Sept
HK$891
HK$980 total
11 Sept - 12 Sept
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,184 reviews)
Comfortable stay near the airport
"The hotel is most convenient for the Tocumen airport with a regular free bus . It is of a high quality as over the last few years it has improved greatly , especially the breakfast service and choice in restaurant . As primarily it should be used only with being near to the airport it does not have ..."

Reviewed on 23 Aug 2025

Crowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
The price is HK$1,048 per night from 9 Sept to 10 Sept
HK$1,048
HK$1,152 total
9 Sept - 10 Sept
includes taxes & fees
Stay at this 4-star spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...
8.4/10 Very Good! (933 reviews)
"Everyone was very nice and accommodating. The staff was primarily bilingual, offered to help with anything needed, and offered water bottles as part of the service."

Reviewed on 21 Aug 2025

Sheraton Grand Panama
See all 1,516 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Santa Ana

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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Casco Viejo
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San Felipe

While visiting San Felipe, you might make a stop by sights like Metropolitan Cathedral of Panama and Interoceanic Canal Museum.

San Felipe
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El Chorrillo

While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Metropolitan Cathedral of Panama are some notable places to visit nearby.

El Chorrillo
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Curundu

While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.

Curundu
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Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.

Calidonia
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Balboa

The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.

Balboa

Santa Ana