Santa Cruz hotels in Querétaro

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30 Dec - 31 Dec
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31 Dec - 1 Jan
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Santa Cruz hotels

Lobby
Dos Patios Querétaro Curamoria Collection

Dos Patios Querétaro Curamoria Collection

Dos Patios Querétaro Curamoria Collection
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (129)
"Spacious and clean room. Great service from Valet employees. "
United States
Alfredo
The price is HK$797
HK$953 total
includes taxes & fees
2 Jan - 3 Jan 2026
Dos Patios Querétaro Curamoria Collection
Interior
Mesón de San Andrés

Mesón de San Andrés

Mesón de San Andrés
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (115)
"Love it! "
United States
EFREN
The price is HK$423
HK$506 total
includes taxes & fees
1 Jan - 2 Jan 2026
Mesón de San Andrés
Terrace/patio
Hotel Casa Miranda

Hotel Casa Miranda

Hotel Casa Miranda
2.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (4)
"La atencion es excelente, no asi las instalaciones. El salir de la habitacion para el baño y que este tapado no es muy buena experiencia. Le falta identificacion en la parte de afuera, son aspectos a mejorar "
Mexico
FERNANDO
The price is HK$331
HK$395 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Casa Miranda
Hallway
Hotel Boutique Casa Altamira

Hotel Boutique Casa Altamira

Hotel Boutique Casa Altamira
3.5 star property
Santa Cruz
8.8 out of 10, Excellent, (360)
"Very nice boutique hotel in one of the city center’s main dinning zones. The rooms are new and clean, the parking is good and the neighborhood is pretty"
United States
Ulises
Hotel Boutique Casa Altamira
Premium bedding, blackout curtains, soundproofing, iron/ironing board
Casa Realm

Casa Realm

Casa Realm
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (28)
"Nice place to stay "
United States
Oscar
The price is HK$362
HK$432 total
includes taxes & fees
12 Jan - 13 Jan 2026
Casa Realm
Terrace/patio
Cinco de Mayo Hotel

Cinco de Mayo Hotel

Cinco de Mayo Hotel
2.5 star property
Santa Cruz
7.6 out of 10, Good, (310)
"Kind of an unbeatable location in the historic center of Queretaro. Simple, clean, decent value. "
United States
Shaun
The price is HK$183
HK$219 total
includes taxes & fees
13 Jan - 14 Jan 2026
Cinco de Mayo Hotel
Egyptian cotton sheets, premium bedding, down duvets, minibar
Hotel Suites Sofia

Hotel Suites Sofia

Hotel Suites Sofia
3.0 star property
Santa Cruz
8.4 out of 10, Very good, (46)
"Perfect place for our needs"
United States
Joseph
The price is HK$541
HK$646 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Suites Sofia
Exterior
Hotel Úrsula Concept

Hotel Úrsula Concept

Hotel Úrsula Concept
3.0 star property
Santa Cruz
8.6 out of 10, Excellent, (14)
"It is very clean, the bed was great and all in an historic home that has been converted to a charming family run boutique quality hotel. It is very close to an historic church with its huge plaza filled with families and activities and comfortable benches."
United States
Steven
The price is HK$651
HK$778 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hotel Úrsula Concept
Sun deck
Hotel & Spa La Mansión del Burro Azul

Hotel & Spa La Mansión del Burro Azul

Hotel & Spa La Mansión del Burro Azul
3.5 star property
Santa Cruz
8.4 out of 10, Very good, (442)
"The place is absolutely beautiful and original. "
United States
Martha
The price is HK$374
HK$446 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel & Spa La Mansión del Burro Azul
Hallway
Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (235)
"Unique boutique hotel with eccentric decor and spacious room. Centrally located "
United States
Elsa
The price is HK$624
HK$746 total
includes taxes & fees
14 Jan - 15 Jan 2026
Casa Brunella Hotel Boutique
Living area
Casa Marina

Casa Marina

Casa Marina
2.0 star property
Santa Cruz
The price is HK$405
HK$616 total
includes taxes & fees
26 Jan - 27 Jan 2026
Casa Marina
Bar (on property)
Domun Hotel

Domun Hotel

Domun Hotel
3.5 star property
Downtown Querétaro, 2.2 km from Santa Cruz
9.6 out of 10, Exceptional, (1003)
"We always like staying there, breakfast is unbelievable!!"
United States
Ricardo
The price is HK$518
HK$619 total
includes taxes & fees
2 Jan - 3 Jan 2026
Domun Hotel
View from property
Hacienda Jurica by Brisas

Hacienda Jurica by Brisas

Hacienda Jurica by Brisas
4.0 star property
Jurica, 11.4 km from Santa Cruz
9.2 out of 10, Wonderful, (1246)
"Staff and food amazing, hotel infrastructure well maintained "
United States
Marco
The price is HK$778
HK$930 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hacienda Jurica by Brisas
Hallway
Hotel Patio Santiago

Hotel Patio Santiago

Hotel Patio Santiago
4.5 star property
Centro Histórico, 0.6 km from Santa Cruz
9.4 out of 10, Exceptional, (412)
"Hotel is located in great area, easy walking distance from center. Staff is very friendly. Rooms are very clean and spacious. Would recommend staying here ☺️"
United States
Atalie
Hotel Patio Santiago
Exterior
One Querétaro Aeropuerto Hotel

One Querétaro Aeropuerto Hotel

One Querétaro Aeropuerto Hotel
3.0 star property
17.6 km from Santa Cruz
7.8 out of 10, Good, (1003)
"Great location from the airport. Clean and perfect for a night or two. "
United States
Maria Trinidad
The price is HK$544
HK$650 total
includes taxes & fees
5 Jan - 6 Jan 2026
One Querétaro Aeropuerto Hotel
Premium bedding, down duvets, in-room safe, individually decorated
Hotel Casa Once

Hotel Casa Once

Hotel Casa Once
3.5 star property
Centro Histórico, 0.5 km from Santa Cruz
9.6 out of 10, Exceptional, (289)
"Amazing hotel "
United States
lizette
The price is HK$748
HK$894 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Casa Once
Exterior
Fiesta Inn Express Queretaro Constituyentes

Fiesta Inn Express Queretaro Constituyentes

Fiesta Inn Express Queretaro Constituyentes
3.0 star property
Mercurio, 1.1 km from Santa Cruz
9.0 out of 10, Wonderful, (1001)
"Excelente hotel "
Mexico
Nora
The price is HK$634
HK$758 total
includes taxes & fees
9 Jan - 10 Jan 2026
Fiesta Inn Express Queretaro Constituyentes
Terrace/patio
Casa Santiago Hotel Boutique

Casa Santiago Hotel Boutique

Casa Santiago Hotel Boutique
3.5 star property
Centro Histórico, 0.7 km from Santa Cruz
9.4 out of 10, Exceptional, (199)
"Excelente "
United States
Hector
Casa Santiago Hotel Boutique
Front of property
HS HOTSSON Hotel Querétaro

HS HOTSSON Hotel Querétaro

HS HOTSSON Hotel Querétaro
4.0 star property
Centro Sur, 4 km from Santa Cruz
9.0 out of 10, Wonderful, (1002)
"Really nice hotel!"
United States
RICARDO
The price is HK$832
HK$994 total
includes taxes & fees
1 Jan - 2 Jan 2026
HS HOTSSON Hotel Querétaro
Breakfast, lunch, dinner served; Regional cuisine
Hotel Hidalgo

Hotel Hidalgo

Hotel Hidalgo
3.0 star property
Centro Histórico, 0.9 km from Santa Cruz
8.6 out of 10, Excellent, (863)
"The room was great very clean the staff was very helpful. Super convenient location "
United States
Michele
Hotel Hidalgo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.
Mexico showing heritage elements and mountains

Downtown Querétaro

Downtown Querétaro is known for its ample dining options, and you can make a stop by Zenea Garden and Plaza de Armas while in the area.

Juriquilla

Juriquilla is noteworthy for its restaurants, and you can make a stop at top attractions like Plaza Juriquilla and Plaza Ubika.

Queretaro which includes a city

Centro Histórico

Unique features of Centro Histórico include the historical sites and museums. Make a stop by Zenea Garden or Plaza de Armas while you're exploring the area.

Jurica

Jurica is noteworthy for its shopping, and you can make a stop at top attractions like Antea Lifestyle Center and Urban Center Shopping Mall.

Church of Santa Maria showing a church or cathedral and heritage architecture

Downtown Tequisquiapan

You'll enjoy the monuments and shopping in Downtown Tequisquiapan. You might want to make time for a stop at Tequisquiapan Handicraft Market or La Pila Park.

Top Santa Cruz Hotel Reviews

Casa Inn Premium Hotel Queretaro

Casa Inn Premium Hotel Queretaro

10/10 Excellent
"The service was great "
Martha 3-night trip
Posted 2 days ago
Casa Inn Premium Hotel Queretaro

Frequently asked questions

What is Santa Cruz like?
Travellers to Querétaro's Santa Cruz neighbourhood will be sure to enjoy a stay here. Are you looking for Santa Cruz travel tips? Make sure that you visit Aqueduct of Santiago de Querétaro and Templo y Convento de la Santa Cruz while you're in the neighbourhood.
Where is the best place to stay in Santa Cruz?
Based on Expedia customer reviews, Hotel Boutique Casa Altamira is the highest ranked property in Santa Cruz. This hotel is a short 13-minute walk from Aqueduct of Santiago de Querétaro, and it offers free parking and free WiFi. Other top choices in the neighbourhood include Hotel & Spa La Mansión del Burro Azul and Hotel Suites Sofia.
How many hotels are there in the Santa Cruz area?
Expedia has 46 hotels and other accommodation options in Santa Cruz to choose from, making this an ideal home base for exploring the greater Querétaro area.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best options available in Santa Cruz.
What is there to do around this Querétaro neighbourhood?
Explore Santa Cruz's landmarks such as Aqueduct of Santiago de Querétaro, Templo y Convento de la Santa Cruz and Arches Viewpoint and learn about the local history. You could also plan a visit to Convent and Temple of Santa Cruz or Querétaro Contemporary Art Museum while you're in the neighbourhood. Plaza de Los Fundadores, Casa de la Zacatecana Museum and Ignacio Mena Rosales House of Culture are just a few of the places to visit in and around Santa Cruz. Plaza de Armas and Querétaro Regional Museum are also worth a visit when you're out sightseeing in Querétaro.

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