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Check prices for these dates

Next weekend
5 Sept - 7 Sept
In two weeks
12 Sept - 14 Sept
In one month
26 Sept - 28 Sept
In two months
24 Oct - 26 Oct

Our top choices for Santee holiday homes

Private Dock + Pool Table: Lake Marion Getaway
Dining

Private Dock + Pool Table: Lake Marion Getaway

9.0 out of 10, Wonderful, (2)
"Great property, we will return and highly recommended."
Private Dock + Pool Table: Lake Marion Getaway
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Interior

Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy

9.8 out of 10, Exceptional, (88)
"Wonderful Location. We were there for a Baby Shower and Visit with close friends. We thoroughly enjoyed the relaxing atmosphere and beautiful view of the lake."
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Marina

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

9.8 out of 10, Exceptional, (237)
"It is our 4th time there and It was absolutely perfect! "
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Archie's Lake Daze Cottage
Property grounds

Archie's Lake Daze Cottage

10.0 out of 10, Exceptional, (79)
"Have stayed here a few times never disappoints"
Archie's Lake Daze Cottage
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Property grounds

Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.

10.0 out of 10, Exceptional, (7)
"This property was perfect for a little lake time during spring break. It was very peaceful and family friendly. The porch was our favorite part!"
Waterfront with dock, less than 5 min to boat landing, gas, ABC and restaurant.
Wyndham Vacation Resorts Lake Marion
Exterior

Wyndham Vacation Resorts Lake Marion

4.0 star property
9.2 out of 10, Wonderful, (19)
"Friendly staff. Excellent accomodations. Peaceful and beautiful vacation."
Wyndham Vacation Resorts Lake Marion
Cozy & Peaceful 3 bed 2 bath On the Water
Fridge, microwave, oven, stovetop

Cozy & Peaceful 3 bed 2 bath On the Water

10.0 out of 10, Exceptional, (36)
"We have ateyed twice now and I have been impressed both times. The place is alway clean and comfortable. Im sure we will be back!"
Cozy & Peaceful 3 bed 2 bath On the Water
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Interior

Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion

2.0 star property
9.6 out of 10, Exceptional, (5)
"We really enjoyed staying here. There was plenty of space for parking cars/boats. The house was clean and spacious and had everything that we needed. The host was responsive when we had questions. Everyone that we met was very nice. We would definitely stay here again. "
Charming 4-bedroom WATERFRONT house with AC and WiFi on Lake Marion
Lake Marion Lakehouse with 180° lake view
Exterior

Lake Marion Lakehouse with 180° lake view

10.0 out of 10, Exceptional, (68)
"I would stay here again. Great location."
Lake Marion Lakehouse with 180° lake view
Beautiful lake home to make your family vacation extra special!
Fridge, microwave, oven, stovetop

Beautiful lake home to make your family vacation extra special!

9.0 out of 10, Wonderful, (56)
"Our family had the best weekend drinking coffee in the morning on the porch.Guys fishing and family time at night playing trivia on tv. Thank you Wendy for such a beautiful place we will be back soon!"
Beautiful lake home to make your family vacation extra special!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Smart TV, offices

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10.0 out of 10, Exceptional, (34)
"We needed a place with two separate bedrooms. This property fit the bill. Perfect for our trip. Nice accommodations. Would definitely recommend this property. "
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Beautiful Cottage between Lake Moultrie and Lake Marion
Smart TV, video games, DVD player, books

Beautiful Cottage between Lake Moultrie and Lake Marion

9.8 out of 10, Exceptional, (141)
"Property as described! Great stay!"
Beautiful Cottage between Lake Moultrie and Lake Marion
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Microwave, oven, stovetop, dishwasher

Taw Caw Creek Rental - perfect for fishermen - NO PETS

10.0 out of 10, Exceptional, (24)
"Joseph responded quickly to any questions and place was very clean, easy access with boats wide driveway , had most things needed in kitchen . "
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Interior

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

10.0 out of 10, Exceptional, (153)
"We enjoyed a great weekend of fishing and the NASCAR race. Our stay was fabulous, and we look forward to coming back! "
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
Dining

Lake Marion Home: Kayaks, Dock, Waterfront Fun!

9.4 out of 10, Exceptional, (8)
"This property was a very nice getaway for my friend and I. We enjoyed the quite neighborhood and sitting on the back porch enjoying the early fall weather. Hope to stay again in the future. "
Lake Marion Home: Kayaks, Dock, Waterfront Fun!
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Fridge, microwave, oven, stovetop

6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates

7.2 out of 10, Good, (12)
"Wonderful place to stay with a group. Rustic but has everything you need. Very comfortable. "
6 Bedrm, 4 full bath + 2 half bath Lake Marion Waterfront Home with 2025 updates
Lake Marion Getaway!
TV

Lake Marion Getaway!

2.0 star property
9.2 out of 10, Wonderful, (38)
"Very nice host. Place was clean and had plenty of room. Family enjoyed their stay. "
Lake Marion Getaway!
Lake Marion in South Carolina.
Property grounds

Lake Marion in South Carolina.

7.8 out of 10, Good, (9)
"Really enjoyed , good , nice place and good communication also was very clean"
Lake Marion in South Carolina.
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Exterior

The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.

10.0 out of 10, Exceptional, (39)
"Very nice place to stay. We had everything we needed for the comforts of home. "
The Lake House at Turtle Cove: Cozy relaxing lake home with dock on wooded lot.
Jewel on the Lake - Relaxing Lakefront Home
Games room

Jewel on the Lake - Relaxing Lakefront Home

9.6 out of 10, Exceptional, (28)
"Very comfortable house in a nice lake cove.Loved the large family room with the combo pool/ air hockey table. House had everything we needed for a short stay. Great communication with the hosts. Very relaxing stay!"
Jewel on the Lake - Relaxing Lakefront Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Find out more about Santee

Santee Vacation Homes information

Number of reviews
143
Accommodation
83 Vacation Homes
Lowest Price
Highest Price