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Southeast Missouri 2 Stars Hotels

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Check availability on Southeast Missouri 2 Star Hotels

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Southeast Missouri 2-star hotels

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A gym with cardio equipment, a bench press, and a squat rack.
A hotel reception area with a glass partition, a reception desk, and a digital kiosk.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.

1. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
ILUNGA
HK$458
HK$498 total
includes taxes & fees
13 Sept - 14 Sept
Baymont Inn and Suites by Wyndham Farmington, MO
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A multi-story hotel with a mix of brick and red facade, featuring a Holiday Inn Express sign.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
HK$776
HK$876 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel lobby with a seating area, a reception desk, and a dining area.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.
A hotel room with a shower, a bathtub, a toilet, a bed, a desk, a chair, and a television.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Clyde
HK$474
HK$554 total
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn Festus - St Louis South
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.
A motel with a prominent '66' sign, large windows, and a flat roof.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

4. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
HK$619
HK$693 total
includes taxes & fees
24 Sept - 25 Sept
Motel 6 Poplar Bluff, MO
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.

5. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Lori
HK$513
HK$585 total
includes taxes & fees
30 Aug - 31 Aug
Days Inn and Suites by Wyndham Sikeston
A hotel room with two beds, a TV, a desk, and a wardrobe.
A building with a sign that reads "The Farmstead."
A spacious lobby with a reception desk, a chandelier, and a large window.
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.

6. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Mary
HK$633
HK$720 total
includes taxes & fees
28 Aug - 29 Aug
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
An indoor swimming pool with clear water, tiled walls, and a metal ladder.

7. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
HK$666
HK$795 total
includes taxes & fees
27 Sept - 28 Sept
Candlewood Suites Cape Girardeau by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
HK$564
HK$637 total
includes taxes & fees
31 Aug - 1 Sept
Pear Tree Inn Cape Girardeau West
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.
An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

9. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
HK$776
HK$879 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

10. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Kevin
HK$735
HK$837 total
includes taxes & fees
28 Aug - 29 Aug
Best Western Plus Sikeston I-55
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

11. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Jeffrey
HK$797
HK$902 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Sikeston
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

12. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
HK$733
HK$821 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Poplar Bluff
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.
A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.

13. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Justen
HK$807
HK$923 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A Holiday Inn Express & Suites building with a covered entrance and multiple windows.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.
A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

14. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Kristen
HK$760
HK$870 total
includes taxes & fees
3 Sept - 4 Sept
Holiday Inn Express & Suites Perryville by IHG
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.
A spacious hotel lobby with a dining area, kitchen, and large windows.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

15. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Susan
HK$860
HK$936 total
includes taxes & fees
6 Sept - 7 Sept
Crown Pointe Lodge, BW Signature Collection
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

16. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Darlene
HK$701
HK$797 total
includes taxes & fees
6 Sept - 7 Sept
Tru By Hilton Cape Girardeau
A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.
A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.
A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.
A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

17. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
Perryville
United States
Elizabeth
HK$506
HK$580 total
includes taxes & fees
15 Sept - 16 Sept
Super 8 by Wyndham Perryville
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

18. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
HK$485
HK$547 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A reception area with a wooden counter, a desk, and a computer.
A laundry area with two washing machines and a dryer.
A motel with a covered parking area, a brick facade, and a sign indicating it is number 8.

19. Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
Potosi
United States
Ross
HK$456
HK$498 total
includes taxes & fees
6 Sept - 7 Sept
Super 8 by Wyndham Potosi
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

20. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
HK$765
HK$859 total
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn By Hilton Dexter
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
HK$784
HK$884 total
2 Sept - 3 Sept
includes taxes & fees
9.6/10 Exceptional! (1,003 reviews)
Drury Plaza Hotel Cape Girardeau Conference Center
Baymont by Wyndham Festus

Baymont by Wyndham Festus

1200 W. Gannon Drive Festus MO
HK$522
HK$597 total
21 Sept - 22 Sept
includes taxes & fees
Baymont by Wyndham Festus
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
HK$737
HK$847 total
14 Sept - 15 Sept
includes taxes & fees
9.6/10 Exceptional! (1,001 reviews)
Drury Inn & Suites Sikeston, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Cheyenna 1-night trip
Posted 7 days ago
Days Inn and Suites by Wyndham Sikeston
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"Clean and nice."
Douglass 1-night trip
Posted 10 days ago
Motel 6 Poplar Bluff, MO

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