Are there any 5-star holiday rentals in Florida Keys?

Although there aren't any 5-star holiday rentals in Florida Keys on our site, we have a range of properties that promise a terrific getaway. Find one that matches your needs by checking out our holiday rentals in Florida Keys .

5 Stars Hotels in Florida Keys: Special Rates & Discounts

A beach with palm trees, people relaxing on chairs, and colorful kayaks.

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Our top choices for Florida Keys 5-star hotels

A bathroom with a large bathtub, a view of the sea, and a pier with boats.

1. Cheeca Lodge & Spa

Matecumbe

Brandon

HK$2,174 total

includes taxes & fees

19 Nov - 20 Nov

An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.

2. Isla Bella Beach Resort & Spa

Marathon

Clinton

HK$2,454 total

includes taxes & fees

29 Nov - 30 Nov

A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.

3. The Islands of Islamorada

Matecumbe

Catherine

HK$6,610 total

includes taxes & fees

30 Nov - 1 Dec

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.

Reefhouse Resort & Marina

103800 Overseas Hwy Key Largo FL

HK$1,718

HK$2,247 total

29 Nov - 30 Nov

includes taxes & fees

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys

A beach with a historic brick fort, a small seaplane, and a group of people walking along the shore.

Top Florida Keys Hotel Reviews

Isla Bella Beach Resort & Spa

10/10 Excellent

"Amazing hotel"

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?

How much you pay for a 5-star hotel in Florida Keys depends on factors like when you plan to go and the length of your stay. A top tip for bagging an awesome deal? Use our pricing filters to check out the available accommodation for your chosen dates.

Search for the lowest price per night from HK$2,247

What makes a hotel 5 stars in Florida Keys?

Impeccable guest service is integral to every 5-star hotel in Florida Keys. From the second you arrive, staff ensure your every need is met, whether recommending activities or providing a turn-down service. What's more, hotels must feature superior conveniences to meet the standard for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, swimming pools, gastronomic restaurants and knowledgeable concierge.

Are there any 5-star all-inclusive resorts in Florida Keys?

Find a luxurious retreat that includes your room, meals, drinks and entertainment in Florida Keys with the help of our filters. Search for hotels with a 5-star rating and select the "All inclusive" filter. Have a look at what's included in the price. This way, you can take full advantage of all the perks on offer from the moment you arrive.

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Check availability on Florida Keys 5 Star Hotels