A large suspension bridge, industrial cranes, and a calm river.

Panama Canal Zone 5 Stars Hotels

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Check availability on Panama Canal Zone 5 Star Hotels

Tonight
12 Sept - 13 Sept
Tomorrow
13 Sept - 14 Sept
Next weekend
18 Sept - 20 Sept
In two weeks
25 Sept - 27 Sept

Our top choices for Panama Canal Zone 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Lori
HK$1,079
HK$1,187 total
includes taxes & fees
27 Sept - 28 Sept
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.
A modern interior with a decorative ceiling, a person in a white dress, and a blue-lit wall.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
HK$2,085
HK$2,294 total
includes taxes & fees
27 Sept - 28 Sept
Waldorf Astoria Panama
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A terrace with seating and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

3. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Benjamin A
HK$2,064
HK$2,271 total
includes taxes & fees
3 Oct - 4 Oct
JW Marriott Panama
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
HK$996
HK$1,096 total
includes taxes & fees
8 Oct - 9 Oct
Renaissance Panama City Hotel
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

5. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
HK$3,211
HK$3,532 total
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern interior with a central seating area, potted plants, and a staircase.
A modern building with a sign reading 'HYATT REGENCY.'

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Abraham
HK$1,467
HK$1,613 total
includes taxes & fees
19 Sept - 20 Sept
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
PAULA
HK$2,053
HK$2,258 total
includes taxes & fees
13 Sept - 14 Sept
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A high-rise building with a rooftop pool area, surrounded by other buildings.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.

8. W Panama

W Panama
Bella Vista
United States
Nikkia
HK$1,750
HK$1,925 total
includes taxes & fees
25 Sept - 26 Sept
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A marina with boats docked, a city skyline with illuminated buildings, and a visible moon in the sky.
A modern interior with a spiral staircase, a large window, and a seating area.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Kevin
HK$1,858
HK$2,044 total
includes taxes & fees
10 Oct - 11 Oct
Hilton Panama
A hotel with a pool, beach, and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
Canada
Flavio
HK$1,616
HK$1,778 total
includes taxes & fees
25 Sept - 26 Sept
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A person performing a yoga pose in a living room with a large window and a sofa.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
HK$1,660
HK$1,826 total
includes taxes & fees
20 Sept - 21 Sept
Bristol Panama, a Registry Collection Hotel
A rooftop pool with lounge chairs and a city skyline in the background.
A hotel room with two beds, a desk, a chair, a mirror, and a large window.

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
HK$866
HK$952 total
includes taxes & fees
6 Oct - 7 Oct
Waymore Hotel Spa and Casino

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
HK$1,846
HK$2,030 total
includes taxes & fees
4 Oct - 5 Oct
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama Canal Zone.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
HK$996
HK$1,147 total
27 Sept - 28 Sept
includes taxes & fees
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
HK$1,438
HK$1,582 total
11 Oct - 12 Oct
includes taxes & fees
9/10 Wonderful! (1,013 reviews)
Central Hotel Panama Casco Viejo
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
HK$733
HK$807 total
17 Sept - 18 Sept
includes taxes & fees
7.8/10 Good! (1,004 reviews)
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
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Learn more about Panama Canal Zone

Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall.

See all hotels in Panama Canal Zone
A lock canal with ships, a bridge, and a forested island in the distance.
Photo by Sérgio Veludo

Top Panama Canal Zone Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Riu plaza hotel is my number 1 when ever I go panama, I spend my birthday there in August I was surprise with a birthday treat that was very thoughtful of them, i like the environment you have pharmacies food please very peaceful very friendly environment very safe. Staff is very good. You feel protected there because it’s 24 seven service. Big up Riu all the time"
SABRINA 3-night trip
Posted 2 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Panama Canal Zone?
The amount you pay for a 5-star hotel in Panama Canal Zone depends on factors such as when you want to go and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to compare all of the available accommodation for your chosen dates.
  • Search for the lowest price per night from HK$807
What makes a hotel 5 stars in Panama Canal Zone?
Faultless guest service is integral to every 5-star hotel in Panama Canal Zone. From the moment you enter the lobby, staff ensure your every need is met, whether arranging valet parking or providing in-room massage treatments. Additionally, hotels have to offer upscale conveniences to obtain a 5-star rating. These can include deluxe baths, an on-site spa, pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Panama Canal Zone?
Our filter tool is the best way to narrow down what you want. Select "5-star" and "All inclusive" to see the most upscale hotels in Panama Canal Zone where your meals, accommodation, activities and entertainment are included in the price. At these getaways, your trip is pure indulgence from the moment you step foot in the lobby.