A bridge over a muddy river with green trees and hills in the background.

Mississippi County Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Mississippi County holiday rentals

A covered outdoor seating area with stone flooring and chairs, a stone pathway, and a wooden structure.

1. Vacation rental attached to our house out in the country.

Vacation rental attached to our house out in the country.
Union City
10.0 out of 10, Exceptional, (9 reviews)
"The home was spotless, very comfortable and a great location for what we needed."
United States
Sherrie S.
The price is HK$784
HK$1,272 total
includes taxes & fees
5 Nov - 6 Nov
Vacation rental attached to our house out in the country.
A cozy room with a wooden table and chairs, a large window, and a door with a sign.

2. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (44 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is HK$883
HK$1,102 total
includes taxes & fees
7 Nov - 8 Nov
Cozy cabins on beautiful Horseshoe Lake
A small, single-story building with a wooden exterior and large windows.

3. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is HK$883
HK$1,102 total
includes taxes & fees
29 Oct - 30 Oct
The Rested Duck Mallard Room
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

4. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is HK$1,169
HK$2,279 total
includes taxes & fees
4 Nov - 5 Nov
Quiet Country Stay: Modern Home Near Paducah
A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

5. Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (39 reviews)
"Great place in a beautiful location. "
United States
George B.
The price is HK$988
HK$1,580 total
includes taxes & fees
29 Oct - 30 Oct
Peaceful secluded cabin located near Horseshoe Lake
A modern kitchen with a built-in microwave, stainless steel appliances, and a sink.

6. Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (26 reviews)
"Location was great. Beds were so comfortable, place was so clean and nice. Very cute place to stay. Would stay here again!"
United States
Deannena H.
The price is HK$863
HK$1,619 total
includes taxes & fees
2 Nov - 3 Nov
Charming Home just minutes from Interstate and Mall
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

7. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
10.0 out of 10, Exceptional, (4 reviews)
"Host was great. "
United States
Sheila C.
The price is HK$855
HK$2,310 total
includes taxes & fees
3 Nov - 4 Nov
Quiet Country Stay: Modern Home Near Paducah
A room with a pool table, a sofa, and a dining table with chairs.

8. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (5 reviews)
"Great place to stay with our dogs while in town visiting family. We were kept busy by the activities available in the cabin and enjoyed the peace outside. We were tempted to ride the trails, which looked nice, but only didn’t because we opted for mud. High likelihood we will be back. Our dogs were happy and so were we."
United States
Alexia G.
The price is HK$1,412
HK$2,095 total
includes taxes & fees
29 Oct - 30 Oct
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
A wooden interior with a herringbone floor, a sliding barn door, a wooden door with a glass panel, and a window with blinds.

9. Tiny house on the lake with tv free internet walk shower

Tiny house on the lake with tv free internet walk shower
Tiptonville
10.0 out of 10, Exceptional, (1 review)
"Dave was very accommodating and the home was clean."
United States
Katherine P.
The price is HK$1,412
HK$2,404 total
includes taxes & fees
29 Oct - 30 Oct
Tiny house on the lake with tv free internet walk shower
A kitchen with a marble countertop, wooden cabinets, and deer antlers mounted on the wall.

10. Cozy rustic studio near Reelfoot Lake

Cozy rustic studio near Reelfoot Lake
Troy
10.0 out of 10, Exceptional, (1 review)
"Was awesome found this last min b4 we left town"
United States
Gary G.
The price is HK$918
HK$1,201 total
includes taxes & fees
4 Nov - 5 Nov
Cozy rustic studio near Reelfoot Lake
A single-story house with a gabled roof, a front porch with two chairs, and a front door with a decorative glass panel.

11. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is HK$1,569
HK$2,908 total
includes taxes & fees
29 Oct - 30 Oct
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
A compact RV interior with a bed, kitchenette, and seating area.

12. Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.

Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.
La Center
The price is HK$353
HK$756 total
includes taxes & fees
29 Oct - 30 Oct
Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.
A large, single-story building with two open garage-style doors, surrounded by trees with autumn foliage.

13. Guest house and spacious shop located between Discovery Park and Reelfoot Lake

Guest house and spacious shop located between Discovery Park and Reelfoot Lake
Union City
10.0 out of 10, Exceptional, (3 reviews)
"Wonderful place to relax. Home has everything you need. The additional party barn is an added bonus!!"
United States
william P.
The price is HK$1,977
HK$3,024 total
includes taxes & fees
30 Oct - 31 Oct
Guest house and spacious shop located between Discovery Park and Reelfoot Lake
A wooden interior with a dining table, chairs, a sofa, and a fireplace.

14. 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak
10.0 out of 10, Exceptional, (15 reviews)
"Great place to stay"
United States
Steve H.
The price is HK$1,569
HK$3,014 total
includes taxes & fees
29 Oct - 30 Oct
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
A covered outdoor area with a grill, chairs, and a table.

15. Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak
9.4 out of 10, Exceptional, (37 reviews)
"Location was great. We were down for a few days fishing."
United States
Andrew
The price is HK$1,024
HK$1,912 total
includes taxes & fees
31 Oct - 1 Nov
Come and relax at the Refuge at beautiful Reelfoot Lake!
A small, single-story mobile home with a covered porch and a sign that reads "THE HUT".

16. The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed

The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
Hornbeak
9.8 out of 10, Exceptional, (60 reviews)
"Very clean and cozy…def will be back"
United States
Ronnie V.
The price is HK$981
HK$1,907 total
includes taxes & fees
30 Oct - 31 Oct
The Hut. Cozy 2-bedroom mobile home on peaceful Reelfoot Lake with boat shed
A kitchen with a stainless steel stove, a range hood, wooden cabinets, and a herringbone wood backsplash.

17. Charming 3-bedroom house with free wifi and coffee it is close to the lake

Charming 3-bedroom house with free wifi and coffee it is close to the lake
Hornbeak
10.0 out of 10, Exceptional, (11 reviews)
"This place was great! It has everything you need and the neighborhood was quiet. The beautiful view of the lake makes it very peaceful! "
United States
Jamie M.
The price is HK$1,236
HK$2,184 total
includes taxes & fees
30 Oct - 31 Oct
Charming 3-bedroom house with free wifi and coffee it is close to the lake
A kitchen with wooden cabinets, a stainless steel refrigerator, a built-in oven, and a large window.

18. 3-bedroom house in charming Tiptonville with cool AC and washer and dryer

3-bedroom house in charming Tiptonville with cool AC and washer and dryer
Tiptonville
10.0 out of 10, Exceptional, (2 reviews)
"Clean very nice home, great for pets would definitely stay again"
United States
Patsy W.
The price is HK$1,059
HK$1,854 total
includes taxes & fees
2 Nov - 3 Nov
3-bedroom house in charming Tiptonville with cool AC and washer and dryer
A covered patio with a white bench, a glass table, and a fan.

19. Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
Hornbeak
9.8 out of 10, Exceptional, (63 reviews)
"Very clean and very helpful host"
United States
Whitney C.
The price is HK$1,306
HK$2,280 total
includes taxes & fees
29 Oct - 30 Oct
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
A bedroom with a bed, a dresser, a television, and a small table with a plant.

20. Sunkist beach house. Lake side house 3 bedroom house

Sunkist beach house. Lake side house 3 bedroom house
Tiptonville
10.0 out of 10, Exceptional, (5 reviews)
"Great experience!! A quality stay with great communication from Host. Will be back! "
United States
Steven L.
The price is HK$1,765
HK$2,887 total
includes taxes & fees
29 Oct - 30 Oct
Sunkist beach house. Lake side house 3 bedroom house
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mississippi County Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

8/10 Good
"Ice machine was not working, it just out of ice. Everything else was good."
zandra 1-night trip
Posted 18 hours ago
Super 8 by Wyndham Charleston/Sikeston East MO