A wooden cart with large wheels in a desert landscape with ancient, earthen structures in the background.

Mesilla hotels from HK$375

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Sept - 10 Sept
Tomorrow
10 Sept - 11 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Filter by

Star rating

Guest rating

Our top choices for Mesilla hotels

1. Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
Las Cruces
United States
Brandon
HK$927
HK$1,070 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn & Suites Las Cruces I-10

2. Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces
United States
shawn
HK$800
HK$927 total
includes taxes & fees
20 Sept - 21 Sept
Drury Inn & Suites Las Cruces

3. Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
Las Cruces
United States
Omar
HK$786
HK$910 total
includes taxes & fees
27 Sept - 28 Sept
Comfort Inn & Suites Las Cruces Mesilla

4. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Las Cruces
United States
Kathy
HK$423
HK$500 total
includes taxes & fees
27 Sept - 28 Sept
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

5. Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
Las Cruces
United States
Verona R.
HK$875
HK$1,012 total
includes taxes & fees
13 Sept - 14 Sept
Springhill Suites By Marriott Las Cruces

6. Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
Las Cruces
United States
Linda
HK$1,016
HK$1,172 total
includes taxes & fees
27 Sept - 28 Sept
Courtyard by Marriott Las Cruces at NMSU

7. Best Western Mission Inn

Best Western Mission Inn
Las Cruces
United States
Berlinda
HK$565
HK$660 total
includes taxes & fees
15 Sept - 16 Sept
Best Western Mission Inn

8. Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
Las Cruces
United States
Donald
HK$380
HK$450 total
includes taxes & fees
13 Sept - 14 Sept
Days Inn by Wyndham Las Cruces

9. Holiday Inn Express Hotel and Suites Las Cruces by IHG

Holiday Inn Express Hotel and Suites Las Cruces by IHG
Las Cruces
United States
Jose
HK$847
HK$977 total
includes taxes & fees
18 Sept - 19 Sept
Holiday Inn Express Hotel and Suites Las Cruces by IHG

10. Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
Las Cruces
United States
Jacob
HK$621
HK$722 total
includes taxes & fees
13 Sept - 14 Sept
Ramada Hotel & Conference Center by Wyndham Las Cruces

11. Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
Las Cruces
United States
Annette
HK$976
HK$1,126 total
includes taxes & fees
13 Sept - 14 Sept
Home2 Suites by Hilton Las Cruces

12. Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
Las Cruces
United States
Todd
HK$860
HK$995 total
includes taxes & fees
27 Sept - 28 Sept
Hilton Garden Inn Las Cruces

13. Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
Las Cruces
United States
Jessica
HK$869
HK$1,034 total
includes taxes & fees
27 Sept - 28 Sept
Comfort Suites Las Cruces I-25 North

14. Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
Las Cruces
United States
Michael
HK$829
HK$960 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn & Suites Las Cruces I-25

15. Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
Las Cruces
United States
Eric
HK$736
HK$1,067 total
includes taxes & fees
23 Sept - 24 Sept
Hotel Encanto de Las Cruces

16. Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
Las Cruces
United States
Michael
HK$663
HK$772 total
includes taxes & fees
4 Oct - 5 Oct
Comfort Suites University Las Cruces

17. Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
Las Cruces
United States
frances
HK$449
HK$529 total
includes taxes & fees
11 Oct - 12 Oct
Quality Inn & Suites Las Cruces - University Area

18. Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
Las Cruces
United States
Lola
HK$1,090
HK$1,283 total
includes taxes & fees
18 Sept - 19 Sept
Fairfield Inn by Marriott Las Cruces

19. Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
Las Cruces
United States
Deanna
HK$925
HK$1,069 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Express & Suites Las Cruces North by IHG

20. Go 2 hotel by Reliance

Go 2 hotel by Reliance
Las Cruces
United States
Arturo
HK$313
HK$375 total
includes taxes & fees
18 Sept - 19 Sept
Go 2 hotel by Reliance
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesilla attractions

Mesillia Plaza

9.2/10 (5 reviews)
This National Historic Landmark features preserved 19th-century adobe architecture from the Gadsden Purchase era. Browse unique shops, savour authentic cuisine, and experience cultural events in this historic square.
See properties

Fountain Theatre

9.2/10 (19 reviews)
New Mexico's oldest cinema, the Fountain Theatre has showcased independent films since 1905 in a historic adobe building. Enjoy art-house cinema with refreshments while admiring original desert murals.
See properties

Fountain Theater

8.6/10 (14 reviews)
The Fountain Theatre, New Mexico's oldest continuously operating film house, showcases independent and foreign films in a historic 1905 setting. Enjoy fresh popcorn in this intimate cultural landmark.
See properties

San Albino Basilica

This historic Spanish Colonial basilica in Mesilla features intricate stained glass windows and serene ambiance. Attend a morning Mass to experience the community's spiritual heart.
See properties

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla
A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Top Mesilla Hotel Reviews

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

10/10 Excellent
"Clean and spacious"
Kenneth 1-night trip
Posted 6 hours ago
Drury Inn & Suites Las Cruces
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

8/10 Good
"Inexpensive"
Lester 1-night trip
Posted 9 hours ago
Days Inn by Wyndham Las Cruces
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

10/10 Excellent
"Everyone has been so great"
Luisa 2-night trip
Posted 2 days ago
Hilton Garden Inn Las Cruces
Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

10/10 Excellent
"The rooms were very clean. The staff were knowledgeable and helpful. The free breakfast was not tasty. Overall, I would stay there again and recommend it to family and friends."
Diane 2-night trip
Posted 2 days ago
Comfort Inn & Suites Las Cruces Mesilla
Charming Casita in historic Town of Mesilla,  NM  2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

10/10 Excellent
"Wonderful property. Convenient location, very comfortable. No problems at all. Would definitely stay here next time."
Erin A. 2-night trip
Posted 3 days ago
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

8/10 Good
"👍"
Kristina 1-night trip
Posted 4 days ago
Comfort Suites Las Cruces I-25 North
Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

10/10 Excellent
"Great location right off Mesilla Plaza with wonderful hosts!"
Karen K. 4-night trip
Posted 2 weeks ago
Casita Azul, Mesilla Plaza Only Steps Away
Charming Adobe One Block from the Mesilla Plaza

Charming Adobe One Block from the Mesilla Plaza

10/10 Excellent
"We absolutely LOVED our stay! It was perfectly located within walking distance to the plaza which was perfect for our early morning walks. The house felt spacious and cozy and the host had everything you could need for a wonderful stay. The back patio was private and a perfect place to enjoy coffee. We will definitely be back every time we visit Las Cruces!"
Angelica G. 4-night trip
Posted 2 months ago
Charming Adobe One Block from the Mesilla Plaza

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM
HK$380
HK$450 total
13 Sept - 14 Sept
includes taxes & fees
8.2/10 Very good! (1,625 reviews)
Days Inn by Wyndham Las Cruces
Motel 6 Las Cruces, NM - Telshor

Motel 6 Las Cruces, NM - Telshor

2120 Summit Ct Las Cruces NM
HK$436
HK$514 total
14 Sept - 15 Sept
includes taxes & fees
7.2/10 Good! (1,000 reviews)
Motel 6 Las Cruces, NM - Telshor
Best Western Mission Inn

Best Western Mission Inn

1765 S Main St Las Cruces NM
HK$565
HK$660 total
15 Sept - 16 Sept
includes taxes & fees
Best Western Mission Inn
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

2101 S Triviz Drive Las Cruces NM
HK$663
HK$772 total
4 Oct - 5 Oct
includes taxes & fees
8/10 Very good! (1,005 reviews)
Comfort Suites University Las Cruces
Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

1300 Avenida De Mesilla Las Cruces NM
HK$786
HK$910 total
27 Sept - 28 Sept
includes taxes & fees
8.8/10 Excellent! (1,000 reviews)
Comfort Inn & Suites Las Cruces Mesilla
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

236 N Telshor Blvd. Las Cruces NM
HK$869
HK$1,034 total
27 Sept - 28 Sept
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
Comfort Suites Las Cruces I-25 North

Find out more about Mesilla

Top reasons to visit Mesilla

  • Vibrant Mesilla Plaza: Experience the lively atmosphere of the historic plaza, surrounded by local shops and eateries.
  • Rich Cultural Heritage: Explore the charming streets of Historic Mesilla, steeped in history and vibrant culture.
  • Scenic Outdoor Activities: Venture into nearby parks and enjoy various outdoor adventures amidst stunning landscapes.
  • Art and Education: Visit intriguing art museums that showcase the region's artistic talent and history.
  • Diverse Accommodation Options: Choose from charming bed and breakfasts to modern hotels, catering to all preferences.

Find great hotels near Mesilla

Explore a range of hotel accommodations in Mesilla, New Mexico, where you can find both charming bed and breakfasts and modern hotels. Whether you're seeking a family-friendly getaway, a pet-friendly stay, or facilities catering to business travellers, Mesilla offers various options to suit your needs. Discover the best Mesilla hotels, affordable choices, and those that promise a memorable experience in this unique historic town.

  • Days Inn by Wyndham Las Cruces: A budget-friendly lodging option boasting a guest rating of 8.2 out of 10, Days Inn by Wyndham Las Cruces is situated 3km away from Mesilla. This hotel embraces a practical theme, catering to both business and leisure travellers, including those with pets. Guests appreciate the pet-friendly policies, allowing for a hassle-free stay with furry companions. Amenities include a service animals fee waiver, along with specific allowances for pet weight and fees, ensuring a comfortable environment for all guests.
  • La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain: With a guest rating of 8.2 out of 10, this hotel offers a welcoming atmosphere suitable for families and business professionals alike. Located 3km from Mesilla, La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain is particularly noted for its family-friendly amenities, including complimentary cribs for younger guests. This property also embraces pet-friendly practices, accommodating dogs and cats. The hotel's thoughtful services enhance the overall family experience, making it an excellent choice for those travelling with children and pets.
  • La Quinta Inn by Wyndham Las Cruces Mesilla Valley: Positioned 3km from Mesilla, this budget-friendly hotel focuses on providing a comfortable stay for families, business travellers, and pet owners. It features child-friendly amenities such as window guards and complimentary cribs, ensuring safety and convenience for families. The property allows pets, with specific guidelines for their accommodation. This hotel is well-regarded for its welcoming atmosphere and amenities, making it a solid choice for those seeking a relaxing retreat in the area.

Where to stay near Mesilla

Mesilla offers a delightful blend of history and outdoor adventure, making it an ideal destination for families and explorers alike. Stroll through the charming streets of Historic Mesilla, where you can admire its rich heritage and vibrant culture. Venture into Central Mesilla to enjoy local shops and eateries, or relax in the nearby parks that provide a perfect backdrop for excursions. Whether seeking tranquillity or adventure, Mesilla promises a memorable experience for every traveller.

  • Las Cruces: Situated a mere 5km from Mesilla, Las Cruces is a vibrant city that offers a delightful blend of outdoor adventure and scenic beauty. Known for its year-round appeal, visitors flock here particularly in March, May, and July. The city's proximity to stunning national parks and dunes makes it an ideal destination for those seeking an adventurous experience. Popular venues include shopping centres and educational institutions, ensuring that there's something for everyone. Whether you're hiking in the nearby state park or enjoying the local cuisine, Las Cruces promises an enriching travel experience.
  • Dona Ana: Located 14km from Mesilla, the quaint village of Dona Ana is steeped in culture and history. Similar to its neighbouring towns, Dona Ana sees an influx of visitors during the spring and summer months. This village is perfect for those interested in cultural themes and outdoor activities, with attractions such as historic forts and monuments that tell the tales of the past. Recreational areas provide ample opportunities for leisure and education, making Dona Ana a charming stop for those exploring the region.
  • University Park: Just 5km away from Mesilla, University Park is a small village that boasts a rich cultural scene and beautiful outdoor spaces. Visitors are drawn here for its scenic landscapes and opportunities for exploration, particularly during the peak months of March, May, and July. The village features an art museum, historic college university, and recreational areas that cater to diverse interests. With its arena entertainment facilities and vibrant atmosphere, University Park is an ideal spot for both relaxation and engagement in local culture.

Things to do in Mesilla

Shopping

In the heart of Mesilla, you'll discover charming local shops like The Bean, offering unique gifts and artisanal goods. If you're up for a drive, head to the Mesilla Valley Mall for a wider selection of retail stores and dining options, located around 18km away in Las Cruces.

Recreation

Experience tranquillity at the La Posta de Mesilla, offering rejuvenating spa treatments inspired by local traditions. For outdoor enthusiasts, the nearby Mesilla Valley Bosque State Park provides scenic trails for walking, bird-watching, and a peaceful connection to nature amidst the stunning desert landscape.

Adventure

Explore the scenic beauty of the Mesilla Valley at the nearby Organ Mountains-Desert Peaks National Monument, where hiking trails offer stunning vistas and diverse wildlife. For a thrilling experience, try hot air ballooning to enjoy breathtaking views of the landscape below during sunrise.

Nightlife

Experience the vibrant nightlife of Mesilla at La Posta de Mesilla, where you can savour delicious Mexican cuisine and sip on cocktails. Alternatively, visit the nearby Blue Grasshopper Brewery for a laid-back atmosphere and craft beers, perfect for unwinding after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mesilla

To save money while visiting Mesilla, consider travelling between December and February, when accommodation prices are lower, especially if you book your stay on a Monday. Use Expedia’s search tool to find budget-friendly hotels and consider combining your hotel, flight, and activities for additional savings. Look for eco-certified hotels to support sustainability while keeping costs down. Lastly, always compare prices and check for app deals to secure the best rates for your trip.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Mesilla are December to February, where the prices are slightly lower. This is in comparison to March, May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Mesilla is Monday. The most expensive day to stay in Mesilla is Saturday.
  • Find cheap hotels on Expedia: Expedia's search tool enables you to specify your budget, preferred location, and additional preferences. You can arrange your search results by price, allowing you to view the most affordable hotels first. Additionally, you have the option to refine your search by hotel category; for instance, selecting the Eco-certified filter will display sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can save money by combining your hotel reservations in Mesilla with your flights and activities by opting for an Expedia package.

Find the best attractions in and around Mesilla

Mesilla offers a delightful blend of city-themed and outdoor attractions, making it perfect for a scenic getaway. Key points of interest include the vibrant Mesilla Plaza, the intriguing art museum, and the stunning national state park. Visitors can immerse themselves in the rich culture and history of old Mesilla while enjoying the picturesque surroundings. This charming town is ideal for those seeking a unique and enriching experience in New Mexico.

  • Mesilla Plaza: Experience the vibrant heart of Mesilla at this modern square, where city vibes blend seamlessly with rich history. Enjoy local shops, restaurants, and the lively atmosphere that reflects the town's cultural heritage.
  • Mesilla Valley Bosque State Park: Located 3km from Mesilla, this national park offers stunning outdoor scenery and adventure opportunities. Wander through scenic trails, observe wildlife, and immerse yourself in the tranquil beauty of the bosque ecosystem.
  • Las Cruces Museum of Fine Arts and Culture: Situated 5km away, this art museum showcases diverse exhibitions that highlight regional culture. Engage with captivating artworks and learn about the artistic heritage of New Mexico.

Best time to go to Mesilla

The best time to visit Mesilla is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is sunny with no rain. January is its coolest month on average. At this time, visitor numbers are average and weather is sunny with no rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January44.6°F (7.0°C)No RainSunnyAverageSlightly Low
February49.6°F (9.8°C)No RainSunnyModerately LowSlightly Low
March57.9°F (14.4°C)No RainSunnyModerately HighSlightly High
April65.8°F (18.8°C)No RainSunnyModerately HighAverage
May73.4°F (23.0°C)No RainSunnyAverageSlightly High
June83.8°F (28.8°C)No RainSunnyAverageAverage
July84.6°F (29.2°C)No RainSunnyModerately HighAverage
August82.8°F (28.2°C)No RainSunnyAverageAverage
September76.6°F (24.8°C)No RainSunnyAverageAverage
October66.0°F (18.9°C)No RainSunnyModerately LowSlightly High
November53.8°F (12.1°C)No RainSunnyModerately LowAverage
December45.5°F (7.5°C)No RainSunnyAverageSlightly Low

The nearest major airports for your trip to Mesilla

Reaching Mesilla, New Mexico, is convenient with several nearby airports. Las Cruces International Airport (LRU) is located 11km away, with excellent hotel options such as the 3.5-star Hotel Encanto de Las Cruces, 18km from the airport, and the 3-star Drury Inn & Suites, just 11km away. El Paso International Airport (ELP) is 64km from Mesilla, offering nearby 4-star hotels like The Plaza Hotel Pioneer Park and Stanton House, both 10km from the airport. For those considering Alamogordo, White Sands Regional Airport (ALM) is 98km away, with 3-star options like The Classic Desert Aire Hotel, only 5km from the airport.

Frequently asked questions

What's the best place for a stay in Mesilla?
Located 0.1 mi (0.2 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.
What are some of the best holiday rentals that Mesilla has to offer?
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis: This holiday home rental outside of Mesilla offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a stovetop and a microwave, so that you can cook with friends or family. See all vacation rentals in Mesilla.
If I need to cancel my hotel reservation in Mesilla, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.
What are some hotels with pools in Mesilla?
Hotel Encanto de Las Cruces: Offers 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.
What is staying in Mesilla like?
Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 12 hotels and other accommodation options to choose from. Find out more about Mesilla.
What should I do while I'm visiting Mesilla?
Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.
What's the seasonal weather in Mesilla?
The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.

Explore a world of travel with Expedia