Mississippi River Hotels

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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (361 reviews)
"Staff was really nice and helpful."
United States
rhonda
The price is HK$627
HK$711 total
includes taxes & fees
23 Mar - 24 Mar
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is HK$749
HK$850 total
includes taxes & fees
23 Mar - 24 Mar
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (746 reviews)
"It was ok as a hotel stay for over night, even tho baymont took it over, it isnt any better. The owner i think lives there, there wasnt any towels in our room. I didnt get a friendly vibe from them at all. "
United States
Michelle
The price is HK$493
HK$571 total
includes taxes & fees
23 Mar - 24 Mar
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,005 reviews)
"Tony did a great job at front desk answering all our questions about the room and Hannibal."
United States
Steven
The price is HK$948
HK$1,088 total
includes taxes & fees
26 Mar - 27 Mar
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (170 reviews)
"Great place to stay!"
United States
Sandy
The price is HK$1,114
HK$1,550 total
includes taxes & fees
23 Mar - 24 Mar
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Would highly recommend to anyone needed an excellent hotel"
United States
Elizabeth
The price is HK$859
HK$995 total
includes taxes & fees
12 Apr - 13 Apr
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Staff was awesome and accomodating. Room and price was great. "
United States
Anthony
The price is HK$546
HK$644 total
includes taxes & fees
19 Apr - 20 Apr
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (521 reviews)
"Really cozy place to stay at!"
United States
Yufei
The price is HK$470
HK$533 total
includes taxes & fees
23 Mar - 24 Mar
Economy Inn Wentzville

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is HK$1,323
HK$1,519 total
includes taxes & fees
23 Mar - 24 Mar
Lighthouse Inn & Suites

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (679 reviews)
"The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location. "
United States
Kayleigh
The price is HK$670
HK$793 total
includes taxes & fees
29 Mar - 30 Mar
Comfort Inn & Suites - Hannibal

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very good, (39 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is HK$755
HK$867 total
includes taxes & fees
12 Apr - 13 Apr
Garden House Bed and Breakfast

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,001 reviews)
"Excellent hotel with great bathroom amenities and an excellent breakfast. Our traveling companion said the biscuits and gravy were the best she'd ever had. Highly recommend this hotel and the included breakfast"
United States
Wendy
The price is HK$630
HK$730 total
includes taxes & fees
12 Apr - 13 Apr
Quality Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,001 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is HK$439
HK$504 total
includes taxes & fees
24 Mar - 25 Mar
Motel 6 Hannibal, MO

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
93.8 km from Mississippi River
6.2 out of 10, (1,002 reviews)
"Everything was good "
United States
Carol
The price is HK$533
HK$612 total
includes taxes & fees
19 Apr - 20 Apr
Days Inn by Wyndham St Peters/St Charles

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.8 out of 10, (37 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is HK$517
HK$585 total
includes taxes & fees
23 Mar - 24 Mar
LAKEVIEWINN

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (498 reviews)
"Loved the staff very friendly and welcoming! Room was amazing! "
United States
Lexys
The price is HK$515
HK$576 total
includes taxes & fees
29 Mar - 30 Mar
Baymont by Wyndham Keokuk

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
"Clean rooms, easy check in, friendly staff, awesome location "
United States
Rhonda
The price is HK$484
HK$556 total
includes taxes & fees
29 Mar - 30 Mar
Super 8 by Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,000 reviews)
"Enjoy our stay very nice clean neat breakfast fresh and staff helpful and pleasant "
United States
Tatiana
The price is HK$553
HK$676 total
includes taxes & fees
5 Apr - 6 Apr
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (158 reviews)
"Truth is that this place was a great value. The rooms and inside were very clean and the staff was excellent. Value for price is exceptional. "
United States
James
The price is HK$446
HK$516 total
includes taxes & fees
23 Mar - 24 Mar
Howard Johnson BY Wyndham Hannibal

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (525 reviews)
"Listing was completely false there is no pool that will ever be operational supposed to be a suite that sleeps 4 but hide a bed had no bedding and when I asked for some all they would give me was 2 very old thin blankets no sheet no pillow both the other beds were stained and dirty there was no toilet paper windows were boarded up on building and was just not what they represented online "
United States
Levi
The price is HK$505
HK$581 total
includes taxes & fees
4 Apr - 5 Apr
Sleep Inn Saint Charles North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
361 reviews
View
Interior
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
22 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
746 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,005 reviews
View
Egyptian cotton sheets, premium bedding, pillow-top beds
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
170 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Cultural Experiences: Immerse yourself in local art galleries and historic houses that showcase the region's rich heritage.
  • Outdoor Adventures: Enjoy various sports activities and stunning river views, perfect for the adventurous traveller.
  • Charming Towns: Explore picturesque communities like Allamakee County, offering a warm, family-friendly atmosphere.
  • Scenic Beauty: Witness the breathtaking landscapes and natural beauty along the iconic Mississippi River.
  • Diverse Accommodation: Choose from delightful bed and breakfasts to inviting guesthouses for a memorable stay.

Find great hotels near Mississippi River

Experience the charm of the Mississippi River with a variety of accommodation options that cater to every traveller's needs. From delightful bed and breakfasts to inviting guesthouses, you'll find the perfect setting for a family getaway, a romantic escape, or a historic adventure. Explore budget-friendly choices and specific locations like Cleveland and Dubuque, ensuring a memorable stay along this iconic waterway.

  • Best Western On The River: A perfect blend of comfort and convenience, Best Western On The River caters to both business and family travellers. Located 25.7km from the Mississippi River, this hotel features amenities specifically designed for children, including cribs for a small fee and a safe pool area with a pool gate. Its welcoming atmosphere and range of business services make it an ideal choice for those seeking a productive yet enjoyable stay.
  • Super 8 by Wyndham Bowling Green: Just 24.1km from the Mississippi River, Super 8 by Wyndham Bowling Green offers a delightful stay with numerous dining options including a complimentary daily breakfast. Guests can indulge in entertainment with premium TV channels, a DVD player, and satellite TV, ensuring relaxation after a day of exploration. The hotel's friendly environment is perfect for families and solo travellers alike, providing a comfortable base for your adventures.
  • River's Edge Motel: Located a mere 12.9km from the Mississippi River, River's Edge Motel is an ideal retreat for pet lovers. This welcoming motel allows pets, making it a great choice for those wanting to bring their furry friends along. With specific policies in place for pets, guests can enjoy a hassle-free stay while exploring the scenic riverside. The relaxed atmosphere and accommodating staff ensure a pleasant experience for all visitors.

Where to stay near Mississippi River

The Mississippi River offers a delightful blend of experiences, from the charming towns of Allamakee County to the picturesque streams that flow alongside. Visitors can enjoy the warm, family-friendly atmosphere, perfect for excursions and relaxation. The breathtaking beauty of the Mississippi itself is a sight to behold, making it an ideal destination for those seeking both adventure and tranquility amidst adorable communities and stunning landscapes.

  • Atlas: Nestled a mere 11.3km from the majestic Mississippi River, Atlas is a charming city that beckons travellers year-round. While visitor numbers peak from June to August, Atlas offers a tranquil escape during the quieter months. Renowned for its stunning scenery and outdoor experiences, visitors can explore picturesque landscapes perfect for hiking, picnicking, and photography. Whether you’re seeking a relaxed atmosphere or an adventurous day out, Atlas promises a delightful experience amid nature's beauty.
  • Rockport: Located 12.9km from the Mississippi River, Rockport is a vibrant city that thrives on a seasonal influx of tourists, particularly in May, July, and September. Families flock to Rockport for its engaging city-themed experiences and outdoor activities. With educational venues and a modern college university nearby, Rockport is ideal for those looking to combine leisure with learning. The city’s welcoming atmosphere and variety of recreational options make it a perfect destination for both relaxation and family fun.
  • Frankford: Situated 16.1km from the Mississippi River, Frankford offers a delightful mix of outdoor adventures and city-themed experiences. Although visitor numbers peak in March to April and July, the city remains an inviting destination throughout the year. Families will appreciate the diverse range of activities, including educational attractions, an arcade adventure zone, and a scenic lake. With museums and conference venues adding to its charm, Frankford is a perfect spot for those seeking a blend of culture, entertainment, and leisurely pursuits.

Things to do near Mississippi River

Discover the vibrant attractions along the Mississippi River, where you can enjoy baseball games, live music, and various sports activities. Don’t miss the chance to explore local art galleries and indulge in activities that offer stunning river views. For the adventurous at heart, there are numerous possibilities to engage with the river's natural beauty, making it an ideal destination for a fun-filled getaway.

Shopping

If you're up for a drive, Quincy Mall, located 46.7km away from the Mississippi River, offers a vibrant mix of business, entertainment, and family-friendly options. It's a great spot to find unique gifts and souvenirs to take home from your trip.

Recreation

At Westview Golf Course, enjoy a round of golf surrounded by lush landscapes, just 43.5km from the Mississippi River. Old Orchard Country Club, located 33.8km away, offers excellent sports facilities in a vibrant outdoor setting. Norwoods Golf Club, 32.2km from the river, invites you to relax and play amidst nature.

Adventure

At Greeman Tennis Center, located 48.3km from the Mississippi River, you can immerse yourself in the thrill of tennis amidst vibrant adventure vibes. Whether you're a novice or experienced player, the centre offers a fantastic environment for an exhilarating day of sport and fun.

Nightlife

The nightlife along the Mississippi River offers a charming blend of romance and culture. Enjoy a captivating performance at Bluff City Theater or Planters Barn Theater, both located 25.7km away, where entertainment thrives amidst a vibrant atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mississippi River

To save money on your trip to the Mississippi River, consider visiting between December and February when accommodation prices are lower, and aim to book your stay on a Sunday for the best rates. Utilise Expedia's search tools to find eco-certified hotels and sort results by price to uncover the best deals. Combining your hotel, flights, and activities into an Expedia package can lead to significant savings. Additionally, explore free activities along the river to enhance your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mississippi River are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mississippi River is Sunday. The most expensive day to stay around Mississippi River is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search wizard to refine your preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally-friendly hotels available at this moment. To find the most economical prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can enjoy significant savings by combining your hotel booking along the Mississippi River with your flights and activities through an Expedia package.

Find the best attractions near Mississippi River

The Mississippi River offers a rich tapestry of attractions, including captivating caves, historic houses, and charming lighthouses. Visitors can immerse themselves in the local culture while enjoying outdoor adventures and unique experiences that showcase the region's heritage. Whether you're seeking adventure or a glimpse into history, there are plenty of points of interest to explore along this iconic river.

  • Mark Twain Cave and Cameron Cave: Nestled 22.5km from the Mississippi River, these caves offer an exhilarating outdoor adventure. Explore the fascinating rock formations and the storied past that inspired Mark Twain's literary works.
  • Rockcliffe Mansion: Located 25.7km away, this historic house boasts exquisite architecture and rich cultural heritage. Wander through its grand rooms and gardens, and immerse yourself in the opulence of the 19th century.
  • Mark Twain Memorial Lighthouse: Also 25.7km from the river, this iconic lighthouse stands as a tribute to the famed author. Enjoy scenic views of the river while reflecting on Twain’s enduring legacy and the region's maritime history.

The nearest major airports for your trip to Mississippi River

For a visit to the Mississippi River, you can consider flying into Quincy, IL (UIN-Quincy Regional-Baldwin Field), situated 43.5km away. Notable hotels nearby include the 3-star Holiday Inn Quincy East and Town & Country Inn and Suites, both within 12.9km. Additionally, Fairfield Inn & Suites Quincy is also a good option. Alternatively, St. Louis, MO (SUS-Spirit of St. Louis) is 107.8km from the river, with excellent accommodations like the 4.5-star Ameristar Casino Resort and Spa and the 4-star DoubleTree by Hilton Hotel, both within 11 and 6.4km, respectively. These hotels provide convenient access to their respective airports.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Near Union Station and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.