Best Perryville Hotels in 2026 from HK$560 - Fully Refundable Options

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Our top choices for Perryville hotels

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

A hotel lobby with a seating area, a reception desk, and a bar.

1. Holiday Inn Express & Suites Perryville by IHG

Perryville

David

HK$823

HK$943 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

2. Super 8 by Wyndham Perryville

Perryville

paulette

HK$560

HK$641 total

includes taxes & fees

4 Oct - 5 Oct

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A building with a sign that reads "The Atrium Boutique Hotel".

3. The Atrium - A Boutique Hotel

Perryville

Brian

HK$593

HK$1,251 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

4. Days Inn by Wyndham Perryville

Perryville

Wanda

HK$559

HK$640 total

includes taxes & fees

4 Oct - 5 Oct

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

5. Perryville RV Resort

Perryville

Kevin

HK$521

HK$596 total

includes taxes & fees

30 Sept - 1 Oct

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A breakfast bar with a toaster, coffee maker, and fruit juice dispenser.

6. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

HK$501

HK$574 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A hallway with exposed brick walls, wooden flooring, and a white door.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

7. Urban Lofts

Perryville

Grace

HK$1,341

HK$2,151 total

includes taxes & fees

28 Sept - 29 Sept

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

A room with a white door, a radiator, a blue carpet, and a mural on the wall.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

8. The Mediterranean House 1858

Perryville

HK$1,277

HK$3,196 total

includes taxes & fees

28 Sept - 29 Sept

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

9. Drury Inn & Suites Jackson MO

Jackson

Thomas

HK$667

HK$705 total

includes taxes & fees

29 Sept - 30 Sept

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

HK$660

HK$714 total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A gym with treadmills, a weight machine, and exercise balls.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

11. Baymont by Wyndham Chester IL

Chester

Keng

HK$723

HK$802 total

includes taxes & fees

6 Oct - 7 Oct

A modern retail area with a display of local items and snacks.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

12. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

HK$701

HK$798 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

A conference room with tables, chairs, a flat-screen TV, and a sign indicating amenities.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

13. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Lauren

HK$823

HK$914 total

includes taxes & fees

26 Oct - 27 Oct

A row of single-story houses with attached garages, a paved driveway, and a clear sky.

A hotel dining area with tables and chairs, a kitchen area, and a flat-screen TV mounted on the wall.

A hotel room with two beds, a desk, a chair, and a window with curtains.

A modern living room with a flat-screen TV, a desk with a computer, two armchairs, a coffee table, and large windows with a view.

14. Microtel Inn & Suites by Wyndham Sainte Genevieve

Ste Genevieve

Samantha

HK$708

HK$832 total

includes taxes & fees

27 Sept - 28 Sept

A motel with a covered entrance, a flag, and a phone number.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

15. Madison Inn Lodge

Fredericktown

Bawan

HK$686

HK$750 total

includes taxes & fees

28 Sept - 29 Sept

A room with a wooden table, two patterned chairs, a framed artwork on the wall, and a window with brown curtains.

A parking lot with a sign for Triangle Inn.

A compact kitchen with black cabinets, a black refrigerator, a microwave, and a sink.

16. Triangle Inn Motel

Ste Genevieve

Gustavo

HK$476

HK$560 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

17. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

HK$593

HK$642 total

includes taxes & fees

22 Oct - 23 Oct

A large, two-story house with a wrap-around porch and a central tower.

A room with a red velvet sofa, a chandelier, a mirror, and a vanity with a sink.

A covered patio with a picnic table, surrounded by a brick pathway and greenery.

A dining room with a wooden table set for four, surrounded by upholstered chairs. A large wooden cabinet with intricate carvings is positioned against the wall.

18. The Conner House B&B

Prairie du Rocher

James

HK$1,225

HK$1,360 total

includes taxes & fees

27 Sept - 28 Sept

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

19. Town House Inn

Jackson

Taylor

HK$559

HK$605 total

includes taxes & fees

27 Sept - 28 Sept

A hotel room with two beds, a nightstand with a lamp, a small window, and curtains.

A small, single-story wooden building with a flat roof, a front door, and windows.

A reception area with a 'KEEP OUT' sign, a clock, an American flag, a wall-mounted television, and a plant.

A room with a sofa, a fan, a door with a sign, and a window.

20. Sparta Motel Near St. Louis / Mississippi River IL

Sparta

Stacey

HK$549

HK$664 total

includes taxes & fees

26 Sept - 27 Sept

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Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

8.8/10 (19 reviews)

This serene Catholic shrine honours the Miraculous Medal with exquisite stained glass and intricate murals. Visitors find spiritual renewal along the peaceful Rosary Walk and Marian Grotto gardens.

See properties

Perryville Country Club

6.6/10 (7 reviews)

This classic 9-hole course features Zoysia fairways and Bent grass greens dating back to 1932. Enjoy a challenging round followed by refreshments at the clubhouse overlooking the scenic Missouri landscape.

See properties

Saint Marys Lake

Saint Marys Lake offers a tranquil escape in Missouri's countryside with serene waters reflecting the changing seasons. Bring a picnic and binoculars to spot local wildlife while enjoying this peaceful local reservoir.

See properties

Missouri's National Veterans Memorial

9.2/10 (14 reviews)

This full-scale replica of the Vietnam Veterans Memorial offers a profound space for reflection away from Washington D.C. Walk the black granite wall inscribed with 58,000 names in Missouri's countryside.

See properties

County Lake State Wildlife Management Area

This peaceful 103-acre reservoir offers exceptional fishing for largemouth bass, bluegill, and hybrid striped bass. Cast your line near brush piles and vegetation beds for the best chance at a memorable catch.

See properties

Feltz Street Park

This community park features a gentle 0.41-mile loop trail and pickleball court. Bring your own equipment and enjoy this peaceful local spot during spring or fall for the best outdoor experience.

See properties

James M. Eddleman Millitary Museum

This veteran-founded museum honours military service through authentic Vietnam War artefacts and personal stories. Explore Jim Eddleman's collection and experience history through the eyes of those who lived it.

See properties

Perryville and related destinations

Historic battlefields and the charming city centre district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Centre and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend.

See all hotels in Perryville

Top Perryville Hotel Reviews

Holiday Inn Express Hotel & Suites Sparta by IHG

8/10 Good

"-"

Baymont by Wyndham Chester IL

8/10 Good

"the room was super hot"

Tru By Hilton Cape Girardeau

10/10 Excellent

"Reserved room for my daughter for her 30th bday and she raved about her experience at this Hotel, from Breakfast to cleanliness to staff."

Drury Inn & Suites Jackson MO

10/10 Excellent

"They did a great job supporting and helping us get the rooms set up for our high school tournament. They were friendly and helpful. We will use them again."

Super 8 by Wyndham Perryville

8/10 Good

"Clean rooms"

Microtel Inn & Suites by Wyndham Sainte Genevieve

8/10 Good

"The design of this line is kind of "euro minimalist". Charming to me, and a nice offset to the old colonial "Habitant" vibe in town. Obviously well managed, but with limited amenities. Basically clean, but a few noticable oversights."

Silo Farm Haus- located in the heart of wine country!

10/10 Excellent

"We were quite impressed with what has been done with the silo! Everything was clean and comfortable upon our arrival. The area was nice and quiet – just what we were looking for away from the city. Sunsets and star gazing were amazing. We would definitely love to come back to the area in the fall when the leaves have turned."

New! Luxury Meets Nature - TreeRise at BaseCamp

10/10 Excellent

"If you are thinking about booking…BOOK.They thought of everything. Our stay was so relaxing and connecting. They had granola kind bars and trail mix waiting for us which was the perfect snacks for our 6 mile hike at Hawn State Park.We loved the stores pack also. Thank you for a perfect weekend!"

Hot Tub & Creek Views: Secluded Perryville Cabin

10/10 Excellent

"Loved this beautiful property"

More cheap stays in Perryville

Super 8 by Wyndham Perryville

1119 Vincent Dr Perryville MO

HK$560

HK$641 total

4 Oct - 5 Oct

includes taxes & fees

8.4/10 Very good! (1,003 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

HK$701

HK$798 total

4 Oct - 5 Oct

includes taxes & fees

9.6/10 Exceptional! (186 reviews)

Baymont by Wyndham Chester IL

2150 State Street Chester IL

HK$723

HK$802 total

6 Oct - 7 Oct

includes taxes & fees

8.4/10 Very good! (422 reviews)

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

120 MUDDY MONSTER ROAD Murphysboro IL

HK$823

HK$914 total

26 Oct - 27 Oct

includes taxes & fees

Holiday Inn Express Hotel & Suites Sparta by IHG

1301 N Market St Sparta IL

HK$831

HK$923 total

25 Oct - 26 Oct

includes taxes & fees

9.2/10 Wonderful! (422 reviews)

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

HK$823

HK$943 total

4 Oct - 5 Oct

includes taxes & fees

Hotels in Perryville with star-rating

Frequently asked questions

What's the best place for a stay in Perryville?

Holiday Inn Express & Suites Perryville by IHG is one of the top choices for your stay based on our traveller data. This hotel offers free breakfast and an indoor pool. Other good choices for your stay include Super 8 by Wyndham Perryville and Days Inn by Wyndham Perryville. See all available top hotels, or vacation rentals in Perryville.

What are some of the best holiday rentals that Perryville has to offer?

Silo Farm Haus- located in the heart of wine country!: This holiday home rental outside of Perryville is in a rural location and offers a Smart TV to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Perryville.

If I need to cancel my hotel reservation in Perryville, will I receive a refund?

Yes, the majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Perryville.

What is the favourite LGBTQ-friendly accommodation in Perryville?

Holiday Inn Express & Suites Perryville by IHG is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. See all available hotels listed as LGBTQ-friendly in Perryville.

What's the best dog-friendly place to stay in Perryville?

Days Inn by Wyndham Perryville is a top hotel for people travelling with their pets, and offers a seasonal outdoor pool and laundry facilities for its human guests. Other good choices for you and your pet's trip include Super 8 by Wyndham Perryville and Perryville RV Resort. See more pet-friendly hotel accommodations in Perryville.

What are some hotels with pools in Perryville?

Quality Inn Perryville I-55 is a top hotel with a seasonal outdoor pool, free breakfast and free WiFi. View all hotels with pools in Perryville.

What is staying in Perryville like?

Visitors can enjoy all that Perryville has to offer, including the wineries, golf courses and coffee shops. Tourists can also enjoy the city's festivals, university setting and parks. In Perryville, there are 26 hotels and other accommodation options to choose from. Find out more about Perryville.

What is there to see in Perryville?

Landmarks like National Shrine of Our Lady of the Miraculous Medal and Missouri's National Veterans Memorial might be worth a visit. Natural beauty is on display at Mark Twain National Forest, Mississippi River and Feltz Street Park. A couple of additional sights to add to your itinerary are Perryville City Hall and Perryville Country Club. Take a look at what more there is to see and do in Expedia's Perryville guide.

What's the seasonal weather in Perryville?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Perryville is 1219 mm.

Perryville hotels from HK$560

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Perryville

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Perryville hotels

1. Holiday Inn Express & Suites Perryville by IHG

2. Super 8 by Wyndham Perryville

3. The Atrium - A Boutique Hotel

4. Days Inn by Wyndham Perryville

5. Perryville RV Resort

6. Quality Inn Perryville I-55

7. Urban Lofts

8. The Mediterranean House 1858

9. Drury Inn & Suites Jackson MO

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

11. Baymont by Wyndham Chester IL

12. Tru By Hilton Cape Girardeau

13. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

14. Microtel Inn & Suites by Wyndham Sainte Genevieve

15. Madison Inn Lodge

16. Triangle Inn Motel

17. Comfort Suites Jackson-Cape Girardeau

18. The Conner House B&B

19. Town House Inn

20. Sparta Motel Near St. Louis / Mississippi River IL

Stay near popular Perryville attractions

National Shrine of Our Lady of the Miraculous Medal

Perryville Country Club

Saint Marys Lake

Missouri's National Veterans Memorial

County Lake State Wildlife Management Area

Feltz Street Park

James M. Eddleman Millitary Museum

Perryville and related destinations

Top Perryville Hotel Reviews

Holiday Inn Express Hotel & Suites Sparta by IHG

Baymont by Wyndham Chester IL

Tru By Hilton Cape Girardeau

Drury Inn & Suites Jackson MO

Super 8 by Wyndham Perryville

Microtel Inn & Suites by Wyndham Sainte Genevieve

Silo Farm Haus- located in the heart of wine country!

New! Luxury Meets Nature - TreeRise at BaseCamp

Hot Tub & Creek Views: Secluded Perryville Cabin

More cheap stays in Perryville

Super 8 by Wyndham Perryville

Tru By Hilton Cape Girardeau

Baymont by Wyndham Chester IL

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express & Suites Perryville by IHG

Hotels in Perryville with star-rating

Frequently asked questions

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