Des Moines Science Center of Iowa Hotels

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Check prices for these dates

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Science Center of Iowa hotels

Property entrance
Des Lux Hotel

Des Lux Hotel

Des Lux Hotel
3.5 star property
Court District, 0.7 km from Science Center of Iowa
9.8 out of 10, Exceptional, (1026)
"We had a wonderful stay and will definitely come back."
United States
Scott
The price is HK$1,182
HK$1,324 total
includes taxes & fees
1 Jan - 2 Jan 2026
Des Lux Hotel
Lobby
Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 0.8 km from Science Center of Iowa
9.6 out of 10, Exceptional, (1066)
"Comfy and stylish lobby and rooms, delicious cafe"
United States
Sarah
The price is HK$1,109
HK$1,242 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Fort Des Moines, Curio Collection by Hilton
Minibar, in-room safe, individually decorated, individually furnished
Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection

Surety Hotel, Autograph Collection
4.0 star property
Court District, 0.5 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1003)
"Great hotel"
United States
Grant
The price is HK$987
HK$1,105 total
includes taxes & fees
16 Jan - 17 Jan 2026
Surety Hotel, Autograph Collection
Exterior
Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 0.8 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1004)
"Staff was amazing. Room, pool, breakfast all spectacular. Enjoyed our stay. Will tell our friends and family and will come back "
United States
Amanda
The price is HK$692
HK$775 total
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Des Moines Downtown by IHG
Exterior
Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines, 0.8 km from Science Center of Iowa
9.2 out of 10, Wonderful, (977)
"Great room, good breakfast. "
United States
Jason
The price is HK$754
HK$844 total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express & Suites Des Moines Downtown by IHG
Games room
Kasa Downtown Des Moines

Kasa Downtown Des Moines

Kasa Downtown Des Moines
4.0 star property
Downtown Des Moines, 0.8 km from Science Center of Iowa
9.2 out of 10, Wonderful, (111)
"Excellent stay! Very clean apartment and safe building."
United States
Bill
The price is HK$727
HK$1,337 total
includes taxes & fees
4 Jan - 5 Jan 2026
Kasa Downtown Des Moines
Exterior
Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown
2.5 star property
Court District, 0.2 km from Science Center of Iowa
8.6 out of 10, Excellent, (1003)
"Clean everything, nice staff, convenient, good breakfast!"
United States
Robert
The price is HK$695
HK$778 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Des Moines Downtown
Lounge
AC Hotel Des Moines East Village

AC Hotel Des Moines East Village

AC Hotel Des Moines East Village
3.0 star property
Historic East Village, 1 km from Science Center of Iowa
9.2 out of 10, Wonderful, (405)
"Hotel was clean and staff friendly."
United States
Cathy
The price is HK$1,173
HK$1,314 total
includes taxes & fees
16 Jan - 17 Jan 2026
AC Hotel Des Moines East Village
Property amenity
Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown
3.0 star property
Court District, 0.2 km from Science Center of Iowa
8.6 out of 10, Excellent, (567)
"Clean and spacious rooms with convenient walkable access to nearby restaurants and attractions. "
United States
Brooks
The price is HK$745
HK$835 total
includes taxes & fees
5 Jan - 6 Jan 2026
Residence Inn Des Moines Downtown
Breakfast, lunch and dinner served
Hilton Des Moines Downtown

Hilton Des Moines Downtown

Hilton Des Moines Downtown
3.5 star property
Downtown Des Moines, 0.9 km from Science Center of Iowa
9.0 out of 10, Wonderful, (1003)
"Clean, good service"
United States
Jennifer
The price is HK$1,013
HK$1,169 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hilton Des Moines Downtown
View from property
Des Moines Marriott Downtown

Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines, 0.7 km from Science Center of Iowa
8.8 out of 10, Excellent, (958)
"Great location, clean, easy check in and check out. "
United States
Emily
The price is HK$1,049
HK$1,175 total
includes taxes & fees
16 Jan - 17 Jan 2026
Des Moines Marriott Downtown
Exterior
Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown

Fairfield Inn & Suites by Marriott Des Moines Downtown
4.0 star property
Downtown Des Moines, 1.2 km from Science Center of Iowa
9.0 out of 10, Wonderful, (398)
"Clean room, quiet, excellent breakfast. "
United States
Randy
The price is HK$762
HK$853 total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott Des Moines Downtown
Premium bedding, down duvets, pillow-top beds, desk
Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel

Renaissance Des Moines Savery Hotel
3.5 star property
Downtown Des Moines, 0.6 km from Science Center of Iowa
8.6 out of 10, Excellent, (1004)
"Great place to stay downtown. "
United States
Wesley
The price is HK$1,049
HK$1,175 total
includes taxes & fees
25 Jan - 26 Jan 2026
Renaissance Des Moines Savery Hotel
Indoor pool
Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines, 1.2 km from Science Center of Iowa
8.8 out of 10, Excellent, (1002)
"Staff was very nice and professional "
United States
Shadienise
The price is HK$709
HK$794 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Event Center
Hypo-allergenic bedding, desk, blackout curtains, iron/ironing board
Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines, 0.7 km from Science Center of Iowa
8.2 out of 10, Very good, (1004)
"Excellent location, very clean, good breakfast & the staff was great!"
United States
Dawn
The price is HK$785
HK$879 total
includes taxes & fees
13 Jan - 14 Jan 2026
Hyatt Place Des Moines/Downtown
Exterior
Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown
3.5 star property
Historic East Village, 0.7 km from Science Center of Iowa
8.2 out of 10, Very good, (1047)
"Great atmosphere and quiet rooms."
United States
MICHAEL
The price is HK$886
HK$992 total
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites Hotel Des Moines Downtown
Exterior
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG
3.0 star property
Downtown Des Moines, 1.6 km from Science Center of Iowa
8.0 out of 10, Very good, (1001)
"Convenient location. Friendly, helpful staff."
United States
Deb
The price is HK$997
HK$1,117 total
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Downtown - Mercy Area by IHG
Iron/ironing board, free WiFi
Cozy Rest Motel

Cozy Rest Motel

Cozy Rest Motel
2.0 star property
Indianola Hills, 2.7 km from Science Center of Iowa
7.8 out of 10, Good, (651)
"This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out."
United States
Chuck
The price is HK$504
HK$565 total
includes taxes & fees
2 Jan - 3 Jan 2026
Cozy Rest Motel
Terrace/patio
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 3.3 km from Science Center of Iowa
9.4 out of 10, Exceptional, (1010)
"Great place to stay and the employees were super nice and helpful"
United States
Amy
The price is HK$726
HK$814 total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton Des Moines at Drake University
Free daily continental breakfast
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Watrous South, 5.3 km from Science Center of Iowa
8.8 out of 10, Excellent, (1003)
"Friendly staff, clean room, comfy bed, and convenient shuttle."
United States
Cullanete
The price is HK$860
HK$963 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Science Center of Iowa Hotel Reviews

Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG

10/10 Excellent
"Staff was amazing. Room, pool, breakfast all spectacular. Enjoyed our stay. Will tell our friends and family and will come back "
Amanda 1-night trip
Posted 4 days ago
Staybridge Suites Des Moines Downtown by IHG

Hotels near other Science Center of Iowa attractions

Principal Park

4.5/5 (64 reviews)
Catch an event at Principal Park during your trip to Des Moines. Experience the area's great live music and lively festivals.
See properties

Des Moines' Downtown Farmers' Market

You can search for that perfect souvenir at Des Moines' Downtown Farmers' Market during your stay in Des Moines. Experience the area's great live music and acclaimed theatre scene.
See properties

Frequently asked questions

What's the area like around Science Center of Iowa?
Science Center of Iowa is located in an area of Des Moines known for its lively festivals. If you're looking for a convenient place to stay, take a look at the 150 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Science Center of Iowa?
Adjacent to Science Center of Iowa, Residence Inn Des Moines Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Hotel Fort Des Moines, Curio Collection by Hilton and Des Lux Hotel.
How many hotels can I expect to find near Science Center of Iowa?
Expedia has 150 hotels and other accommodation options within a mile from Science Center of Iowa.
If I need to cancel the hotel reservation for my stay near Science Center of Iowa, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to view top deals close to Science Center of Iowa.
What can I see and do near Science Center of Iowa?
Des Moines Art Center, World Food Prize Hall of Laureates and Iowa Hall of Pride feature a variety of fascinating exhibits to see while you're in town. Walnut Street Bridge, Salisbury House and Valley Junction are some of the notable landmarks to see in the area. You can check out the local talent at Wooly's, Hoyt Sherman Place and Lauridsen Amphitheater.