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Our top choices for Southeast Missouri holiday homes

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (5 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village

Charming 2-bedroom house with AC, WiFi in serene Van Buren

Charming 2-bedroom house with AC, WiFi in serene Van Buren
Van Buren
9.0 out of 10, Wonderful, (15 reviews)
"It was beautiful and homey. We really enjoyed our stay. "
United States
Jessica
The price is HK$548
HK$1,322 total
includes taxes & fees
24 Mar - 25 Mar
Charming 2-bedroom house with AC, WiFi in serene Van Buren

Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (95 reviews)
"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"
United States
Anonymous traveller
The price is HK$822
HK$1,026 total
includes taxes & fees
24 Mar - 25 Mar
Get Away Acres 1/2 mile off highway 60 extra sanitized

Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (10 reviews)
"Beautiful and perfect for travelers!!!!!"
United States
Elizabeth
The price is HK$599
HK$1,491 total
includes taxes & fees
24 Mar - 25 Mar
Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.6 out of 10, Exceptional, (29 reviews)
"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"
United States
Jody C.
The price is HK$846
HK$1,977 total
includes taxes & fees
24 Mar - 25 Mar
Cozy Three bedroom home in Central Farmington

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
9.0 out of 10, Wonderful, (6 reviews)
"Great place. "
United States
Diana
The price is HK$529
HK$1,159 total
includes taxes & fees
30 Mar - 31 Mar
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (39 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is HK$1,057
HK$1,689 total
includes taxes & fees
5 Apr - 6 Apr
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”
Ste. Genevieve
10.0 out of 10, Exceptional, (69 reviews)
"Great place to stay!"
United States
Lettitia B.
The price is HK$931
HK$1,348 total
includes taxes & fees
24 Mar - 25 Mar
"Little Brick House on Main (1865)”

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (14 reviews)
"Everything was fantastic!"
United States
Nicholas D.
The price is HK$948
HK$1,828 total
includes taxes & fees
30 Mar - 31 Mar
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (28 reviews)
"We have been there three times and it was just as peaceful, clean and exactly what we needed. "
United States
Kimber L.
The price is HK$979
HK$1,194 total
includes taxes & fees
24 Mar - 25 Mar
Clifford's Country Cottage

Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (12 reviews)
"Very clean and well stocked. Host was excellent to communicate with. We would definitely stay again!"
United States
Ken R.
The price is HK$901
HK$1,757 total
includes taxes & fees
24 Mar - 25 Mar
Doc's Cottage - A-Frame in Piggott, AR

Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.
Bloomsdale
10.0 out of 10, Exceptional, (11 reviews)
"What a beautiful fun stay that was a nice quick getaway for us! Everything was perfect from booking, to arrival, to overall stay, we had the best time! "
United States
Blake H.
The price is HK$1,410
HK$2,174 total
includes taxes & fees
24 Mar - 25 Mar
Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (8 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
The price is HK$948
HK$1,828 total
includes taxes & fees
4 Apr - 5 Apr
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (39 reviews)
"The kitchen was fully equipped and clean. Great place to stay when visiting Farmington!"
United States
Linda B.
The price is HK$1,010
HK$1,935 total
includes taxes & fees
24 Mar - 25 Mar
Your home away from home in downtown, historic Farmington!

King Bed, game room minutes away from downtown, golf courses + BIG back yard

King Bed, game room minutes away from downtown, golf courses + BIG back yard
Farmington
10.0 out of 10, Exceptional, (24 reviews)
"Everything about this property was amazing and perfect for our family! They were so helpful with everything and our kids loved it here!!"
United States
Heaven B.
The price is HK$901
HK$1,819 total
includes taxes & fees
5 Apr - 6 Apr
King Bed, game room minutes away from downtown, golf courses + BIG back yard

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.2 out of 10, Very good, (53 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
The price is HK$634
HK$847 total
includes taxes & fees
24 Mar - 25 Mar
Little Blue Cottage on Spanish

The Sutton House 2 blocks from Main Street & Courthouse Square

The Sutton House 2 blocks from Main Street & Courthouse Square
Ironton
10.0 out of 10, Exceptional, (48 reviews)
"Adorable house with everyone you need provided! Super clean and the beds were very comfy. Will stay here again on our next trip to the area. "
United States
Brandi
The price is HK$1,324
HK$1,610 total
includes taxes & fees
30 Mar - 31 Mar
The Sutton House 2 blocks from Main Street & Courthouse Square

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Ironton
10.0 out of 10, Exceptional, (35 reviews)
"enjoyed our stay, nice location to downtown and coffee. "
United States
Aaron L.
The price is HK$1,077
HK$2,093 total
includes taxes & fees
24 Mar - 25 Mar
*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

Cozy Haven Little Hidden Gem Sleeps 4

Cozy Haven Little Hidden Gem Sleeps 4
Ste.Genevieve
9.8 out of 10, Exceptional, (60 reviews)
"Everything was perfect. The host was very responsive and friendly and the house was perfect for our stay. It has lots of character and the perfect amount of upgrades. We will definitely stay here again."
United States
Brenda R.
The price is HK$775
HK$1,650 total
includes taxes & fees
1 Apr - 2 Apr
Cozy Haven Little Hidden Gem Sleeps 4

FS Rental #2 Annapolis, MO Black River

FS Rental #2 Annapolis, MO Black River
Annapolis
7.2 out of 10, Good, (7 reviews)
"Great experience "
United States
West n.
The price is HK$775
HK$1,520 total
includes taxes & fees
24 Mar - 25 Mar
FS Rental #2 Annapolis, MO Black River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Find out more about Southeast Missouri

Southeast Missouri Vacation Homes information

Number of reviews
532
Accommodation
190 Vacation Homes
Lowest Price
HK$847
Highest Price
HK$2,174

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