Photo by Southernmost Illinois Tourism Bureau
Search Vacation Homes in Southern Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Southern Illinois holiday homes
Vintage Charmer on Main Street
Vintage Charmer on Main StreetGreenup
10.0 out of 10, Exceptional, (61 reviews)
"Looking forward to staying again on our return trip home"
Karen B.
The price is HK$668
HK$1,081 total
includes taxes & fees
9 Feb - 10 Feb
Countryside Private Guest Room
Countryside Private Guest RoomFreeburg
10.0 out of 10, Exceptional, (19 reviews)
"Wonderful property with a wonderful host!"
gerry e.
The price is HK$527
HK$725 total
includes taxes & fees
15 Feb - 16 Feb
Cozy Corner Mascoutah
Cozy Corner MascoutahMascoutah
9.6 out of 10, Exceptional, (76 reviews)
"Great stay! Fantastic host "
Allison D.
The price is HK$820
HK$1,532 total
includes taxes & fees
11 Feb - 12 Feb
Secluded treehouse with indoor fireplace
Secluded treehouse with indoor fireplaceMakanda
10.0 out of 10, Exceptional, (21 reviews)
"Had a great stay. The treehouse was unique and a great get away spot while enjoying the local winery’s. We’ll be back for more fun this upcoming fall. "
Nathaniel M.
The price is HK$837
HK$1,384 total
includes taxes & fees
9 Feb - 10 Feb
Cozy home with the right amenities for your visit to our sweet town.
Cozy home with the right amenities for your visit to our sweet town.Nashville
10.0 out of 10, Exceptional, (22 reviews)
"Wonderful quiet place for some of my family to stay during a family weekend."
Nancy M.
The price is HK$757
HK$1,341 total
includes taxes & fees
9 Feb - 10 Feb
Brickway Retreat
Brickway RetreatMattoon
9.8 out of 10, Exceptional, (42 reviews)
"Always super clean and inviting!"
Melinda G.
The price is HK$859
HK$1,408 total
includes taxes & fees
9 Feb - 10 Feb
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shoppingHarrisburg
9.8 out of 10, Exceptional, (24 reviews)
"Great place to stay"
Neil I.
The price is HK$703
HK$1,325 total
includes taxes & fees
9 Feb - 10 Feb
Sweet Farm Stay
Sweet Farm StayFreeburg
10.0 out of 10, Exceptional, (43 reviews)
"We had a very pleasant stay"
Kate
The price is HK$1,172
HK$1,408 total
includes taxes & fees
28 Feb - 1 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find holiday rentals that suit your style
Cabins
Private holiday homes
Save an average of 15% on thousands of hotels when you're signed in
Top Southern Illinois Hotel Reviews
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
Find out more about Southern Illinois
Southern Illinois Vacation Homes information
Number of reviews | 620 |
|---|---|
Accommodation | 386 Vacation Homes |
Lowest Price | HK$725 |
Highest Price | HK$2,691 |
Explore a world of travel with Expedia
- Cabin Rentals in Alto Pass
- B&B in Southern Illinois
- Motels in Highland
- Hotels near Mount Vernon Outland
- Cabin Rentals in Pomona
- Dix Hotels
- Independent Hotels in Centralia
- Hotels near Southern Illinois
- Farmstay in Southwest Illinois
- Pet-Friendly Hotel Hotels in Carlyle
- Hotel with Pool Hotels in Carlyle
- Nashville Hotels
- Apartments in Goreville
- Hotels near Salem Fairgrounds
- Cabin Rentals in Cobden
- Guest Houses in Southwest Illinois
- Lodges in Whittington
- Luxury Hotel Hotels in Southern Illinois
- Sesser Hotels
- Hotels near William Jennings Bryan Boyhood Home and Museum
- Cisne Hotels
- Cabin Rentals in Marion
- Adventure Sport Hotel Hotels in Marion
- Motels in Albion
- Cheap Hotels in Du Quoin
- 3 Star Hotels in Keyesport
- Family Hotel Hotels in Harrisburg
- Noble Hotels
- Cabin Rentals in Waltonville
- Albion Hotels
- 4 Star Hotels in Tamaroa
- Hamilton County Hotels
- Casino Hotel Hotels in Southern Illinois
- Cabin Rentals in Makanda
- Apartments in Pocahontas
- Hotels near Rend Lake College
- Creal Springs Hotels
- Spa Hotel Hotels in Carlyle
- Chalets in Southern Illinois
- Pet-Friendly Hotel Hotels in Marion
- Carlyle Hotels
- Pet-Friendly Hotel Hotels in Mount Vernon
- 4 Star Hotels in Carbondale
- Kinmundy Hotels
- Apartments in Carlyle
- Cabin Rentals in Christopher
- Red Roof Inn Hotels in Carbondale
- Cabin Rentals in Freeburg
- Fairfield Hotels
- Red Lion Hotels in Southwest Illinois
- Cheap Hotels in Carbondale
- 3 Star Hotels in Aviston
- Hotels near William Jennings Bryan Statue
- Cabin Rentals in Southern Illinois
- 4 Star Hotels in Carmi
- Hilton Hotels in Ewing
- Lodges in Herrin
- Motels in Herrin
- Apartments in Chester
- Hotels near Kokopelli Golf Club
- Romantic Hotel Hotels in Carterville
- Apartments in Pinckneyville
- Cheap Hotels in Grayville
- Cabin Rentals in Dix
- 3 Star Hotels in Carmi
- Ava Hotels
- Hotels near Flora City Hall
- Lodges in Enfield
- Cabin Rentals in Ozark
- La Quinta Inn & Suites Hotels in Southern Illinois
- Motel 6 Hotels in Carlyle
- 4 Star Hotels in Sims
- Family Hotel Hotels in Grayville
- Marion Hotels
- 3 Star Hotels in Du Quoin
- Hotels near West Access Marina
- Ina Hotels
- B&B in Highland
- Mount Vernon Hotels
- Cabin Rentals in Carbondale
- 5 Star Hotels in Corinth
- 3 Star Hotels in Odin
- Extended Stay America Hotels in Carlyle