Spa Holidays in Florida Keys 2026

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Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL

3 hours drive from Florida Keys Beaches

Stay at this luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their ...

Pier House Resort & Spa

1 Duval St Key West FL

37 min drive from Florida Keys Beaches

Stay at this beach resort in Key West. Enjoy a full-service spa, a private beach and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...

9/10 Wonderful! (1,277 reviews)

Travellers like: full-service spa, massage, facials, manicures and pedicures

Travellers say...

"Air conditioner did not work well in our room and maintenance had to come change out the unit."

Reviewed on 9 Aug 2026

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL

36 min drive from Florida Keys Beaches

Stay at this beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

See all 8,258 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.