Central San Diego Guest Houses

A red train on tracks, palm trees, and modern buildings.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Central San Diego guest houses

1. Secluded Garden Cottage Walk to Shops + 55” TV

University City

noel o.

HK$2,721 total

includes taxes & fees

17 Aug - 18 Aug

Coffee/tea maker, fridge, microwave, oven

2. Heart of SD | Zoo Nearby | Private Patio | Central

Mid-City

Bronson M.

HK$1,756 total

includes taxes & fees

26 Aug - 27 Aug

1 bedroom, iron/ironing board, free WiFi, bed sheets

3. Modern Loft Retreat - North Park SD

North Park

Ty S.

HK$2,794 total

includes taxes & fees

1 Sept - 2 Sept

Desk, laptop workspace, free WiFi, individually decorated

4. Somerset

Downtown San Diego

Jasper Kyle

HK$1,250 total

includes taxes & fees

13 Aug - 14 Aug

5. El Primero Hotel

Downtown Chula Vista

Roberto

HK$924 total

includes taxes & fees

7 Sept - 8 Sept

6. Vineyard Hacienda

Jamul

Michele

HK$1,387 total

includes taxes & fees

9 Aug - 10 Aug

7. * Private Studio | Cozy Vibes + Relaxing Oasis *

Country Club

HK$2,219 total

includes taxes & fees

1 Sept - 2 Sept

8. Rockaway North - Family Friendly, Garage Parking & Laundry

Mission Beach

Raeann Z.

HK$3,906 total

includes taxes & fees

26 Aug - 27 Aug

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Central San Diego Hotel Reviews

Handlery Hotel

8/10 Good

"Great place with a nice pool area, the pool is large, has a big jacuzzi and access to a bar within 20 steps. Downside is $24 parking fee that is not included in hotel price shown."

Hilton San Diego Mission Valley

8/10 Good

"Our stay was great, clean with a nice view. The bartenders at the bar had good customer service and good drinks. I think the employees should communicate that you need the room key to exit the parking structure and to enter the lobby from the parking lot. The hotel is small but has a lot of floors, there are 3 elevators for the whole building one was down when we were there and it takes a while to go up to your room and to come down, other than that our stay was great. There are a lot of things nearby not too far from the snap dragon if you're there for a concert. They also have a small area to buy snacks and water from which I think is convenient."

Find out more about Central San Diego