Edisto Island Serpentarium

Popular places to visit

Botany Bay Plantation

Botany Bay Plantation

Explore the great outdoors at Botany Bay Plantation, a lovely green space in Edisto Island. Stroll along the beaches in this relaxing area or seek out the fishing spots.

Botany Bay Plantation
Edisto Beach State Park

Edisto Beach State Park

You can take time to visit Edisto Beach State Park during your travels to Edisto Island. Wander the beautiful beaches in this relaxing area.

Edisto Beach State Park
Kiawah Beachwalker Park

Kiawah Beachwalker Park

Explore the great outdoors at Kiawah Beachwalker Park, a lovely green space in Seabrook Island. Wander through the beautiful beaches and seaside in this relaxing area.

Kiawah Beachwalker Park

With These Hands Gallery

You can spend time studying the exhibits at With These Hands Gallery during your travels in Edisto Island. Stroll along the beautiful beaches in this relaxing area or seek out the cycling trails.

With These Hands Gallery

Botany Bay Plantation Heritage Preserve and Wildlife Management Area

Explore the lovely green spaces of Botany Bay Plantation Heritage Preserve and Wildlife Management Area and enjoy the cycling trails in Edisto Island. Wander the beautiful beaches in this relaxing area.

Botany Bay Plantation Heritage Preserve and Wildlife Management Area

Edisto Island Museum

You can spend time studying the exhibits at Edisto Island Museum during your trip to Edisto Island. Wander the beautiful beaches in this relaxing area.

Edisto Island Museum

Top Edisto Island Serpentarium Hotel Deals

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi

Edisto Island
Gorgeous Secluded Island W/Creek & Ocean View w/DOCK & swim! Pet-friendly/Wi-Fi
Paradise Found- Stunning Ocean views + Unique Home

Paradise Found- Stunning Ocean views + Unique Home

Edisto Island
Paradise Found- Stunning Ocean views + Unique Home
Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto

Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto

Edisto Island
Discover 5 Acres of Secluded Luxury on the Marsh and Close to the Beach: Edisto
Incredible custom built escape near beach with amazing ocean views

Incredible custom built escape near beach with amazing ocean views

Edisto Beach
Incredible custom built escape near beach with amazing ocean views
The Marshpad, surrounded by nature, mins to beach in gated community

The Marshpad, surrounded by nature, mins to beach in gated community

Edisto Island
The Marshpad, surrounded by nature, mins to beach in gated community
The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths

The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths

Edisto Island
The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths
Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach

Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach

Edisto Beach
Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach
Oceanfront Showplace - Island Manor

Oceanfront Showplace - Island Manor

Edisto Beach
Oceanfront Showplace - Island Manor
See all 2,073 properties in Edisto Island Serpentarium
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.