Milan San Sebastiano Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for San Sebastiano hotels

A narrow cobblestone street lined with multi-story buildings, featuring balconies and large windows.

A modern kitchen with white cabinets, a red coffee machine, and a dining area with a round table and chairs.

A room with a window overlooking a cityscape, featuring a building with a green dome and a bell tower.

A modern hotel room with a large bed, a desk, and a patterned wall.

1. Oriana Homèl Milano

Centro Storico, 0.1 km from San Sebastiano

Katrina

HK$1,313

HK$1,612 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel room with a large bathtub, a bed, a seating area, and a view of the city at night.

A modern bathroom with a marble backsplash, a glass shower enclosure, and a wooden bench.

A modern living room with leather sofas, a coffee table, and a TV displaying 'AF DUOMO'.

A modern hotel room with a wooden parquet floor, a large bathtub, a dining area with a glass table and chairs, and a living area with sofas and a TV.

2. AF Duomo - Milano Luxury Suites

Centro Storico, 0.3 km from San Sebastiano

Robert

HK$4,173

HK$4,836 total

includes taxes & fees

22 Nov - 23 Nov

A modern bedroom with a wooden ceiling, a large bed with white bedding and orange pillows, a laptop on the bed, a bedside table with a lamp, and a small bench.

A modern kitchen with white cabinetry, a black countertop, and a unique yellow pendant light.

A living room with a grey sofa, yellow cushions, a white coffee table, and a patterned rug.

A modern living room with a white sofa, a TV mounted on a white wall, a dining table with fruit and a cup, and a patterned rug.

3. Heart Milan Apartments - Duomo Colonne

Centro Storico, 0.6 km from San Sebastiano

Ben

HK$1,071

HK$1,345 total

includes taxes & fees

10 Nov - 11 Nov

A modern kitchen with a central island, bar stools, a hanging light fixture, and a wooden ceiling.

A rooftop terrace with a table and chairs, a potted plant, and a view of adjacent buildings.

A modern living room with a sofa, dining table, chairs, and a small coffee table.

A modern kitchen with white cabinets, a black and white checkered floor, a dining table with chairs, a microwave, and a laptop on the table.

4. Palazzo Fulcorina Apartments

Centro Storico, 0.4 km from San Sebastiano

Bogdan

HK$1,298

HK$1,595 total

includes taxes & fees

8 Nov - 9 Nov

A table with two drinks and snacks, surrounded by chairs and a green hedge in the background.

A buffet area with various food items, including cakes, pastries, and a granola bar dispenser.

A modern hotel room with a large bed, a built-in desk, and a large mirror.

A hotel reception area with a marble reception desk, a large window, and a view of the outside.

5. Hotel Milano Castello

Brera, 0.6 km from San Sebastiano

Junghee

HK$1,442

HK$1,709 total

includes taxes & fees

25 Oct - 26 Oct

A hotel entrance with a sign 'Ostello Bello' and a glass door. There are outdoor seating areas with chairs and tables, surrounded by potted plants and flowers.

An outdoor patio with wooden tables and chairs, surrounded by potted plants and hanging lanterns.

A café with a variety of baked goods, a drink menu, and a selection of bottled beverages.

A modern kitchen with a central island, bar stools, a microwave, and a window with a view.

6. Ostello Bello Milano Duomo

0.4 km from San Sebastiano

Juanita

HK$918

HK$1,062 total

includes taxes & fees

22 Nov - 23 Nov

A bedroom with a bed, bedside table, and a mirror.

A hotel room with a bed, a wardrobe, a dining table with chairs, and a window with curtains.

A modern bedroom with a bed, a seating area, and a wardrobe.

A modern interior with a long corridor, wooden panel walls, a seating area with a table, and large windows offering views of greenery.

7. Casa Brivio

Centro Storico, 0.4 km from San Sebastiano

Chandi

HK$2,128

HK$2,508 total

includes taxes & fees

8 Nov - 9 Nov

A building with a sign reading 'CASA LAVENI' and a visible entrance with columns.

A modern interior with dark blue walls, bookshelves, and round tables with stools.

An outdoor seating area with two white cushioned chairs, a small round table with a lamp, and a potted plant.

A modern living room with a sofa, chairs, a coffee table, and a bookshelf.

8. Casa Laveni

Brera, 0.6 km from San Sebastiano

Alexis

HK$2,973

HK$3,394 total

includes taxes & fees

23 Nov - 24 Nov

A spacious lobby with high ceilings, large columns, and a central seating area.

A spacious lobby with large windows, a central chandelier, and a view of the cityscape.

A spacious living room with a sofa, armchair, and ottoman, large windows with curtains, and a view of the cityscape.

An outdoor dining area with tables set for two, surrounded by lush greenery and architectural elements.

9. Palazzo Touring Club Milan, A Radisson Collection Hotel

Centro Storico, 0.4 km from San Sebastiano

Jing

HK$3,221

HK$3,754 total

includes taxes & fees

22 Nov - 23 Nov

The entrance to Hotel Spadari with a glass door, potted plants, and a signboard.

A modern hotel room with a wooden desk, two grey chairs, and a large window with a view of city buildings.

A hotel room with a bed, a chair, a table, and a large mirror.

A buffet table with various pastries and a tiered dessert display in a hotel lobby.

10. Hotel Spadari al Duomo True Stay

Centro Storico, 0.2 km from San Sebastiano

Maurice

HK$1,759

HK$2,111 total

includes taxes & fees

1 Nov - 2 Nov

A classical building facade with a central entrance, large windows, and decorative moldings.

A modern living room with a sofa set, a glass coffee table, and a bookshelf.

A breakfast setup with pastries, coffee, and a vase of flowers in front of a large window with a grid pattern.

A spacious atrium with high ceilings, a central chandelier, and seating areas with blue cushions.

11. Park Hyatt Milano

Centro Storico, 0.4 km from San Sebastiano

Ruth

HK$9,848

HK$11,043 total

includes taxes & fees

12 Nov - 13 Nov

A modern living room with a grey sofa, a dining table, and a TV mounted on the wall.

A modern hallway with a wooden panel wall, a metal sculpture, and a chair.

A modern living room with a sofa, a dining table with chairs, and a TV mounted on the wall.

A hotel room with a bed, pillows, and a view of a tower through a glass door.

12. Heart Milan Apartments - Duomo District

Centro Storico, 0.1 km from San Sebastiano

William

HK$1,282

HK$1,578 total

includes taxes & fees

2 Nov - 3 Nov

A hallway with a modern design, featuring a sign that reads "THE ROOMS BOUTIQUE HOTEL MILANO".

A modern lobby with marble flooring and walls, a staircase, and two elevators.

A modern hotel room with a large bed, bedside lamps, a built-in desk, and a minibar.

A modern restaurant with a long counter, yellow chairs, and a seating area with a sofa and tables.

13. TheROOMS by TheFLOOR Collection

0.3 km from San Sebastiano

"Excellent location and a comfortable stay. TheROOMS by TheFLOOR Collection is clean, modern, and within easy walking distance of the Duomo and major sights. Staff were friendly and helpful, and the room was comfortable with good amenities. The only downsides were some street/tram noise and the slightly confusing entrance—reception is on the third floor of a shared building. Still, a great value base for exploring Milan."

Harvey

HK$1,269

HK$1,563 total

includes taxes & fees

25 Oct - 26 Oct

A historic building with large windows, ornate balconies, and a prominent entrance.

A modern interior with a central table, orange chairs, a bookshelf, and a kitchen area.

A modern bathroom with a large bathtub, a separate shower area, and a vanity with a mirror.

A narrow doorway leading to a bathroom with a red sink and a mirror above it.

14. Palazzo Segreti

Brera, 0.6 km from San Sebastiano

Anna

HK$2,191

HK$2,586 total

includes taxes & fees

25 Oct - 26 Oct

A historic building with a prominent entrance, arched windows, and a balcony with balustrades.

A buffet with various fruits, vegetables, and prepared dishes.

A hotel room with a large bed, a nightstand, a lamp, and a view of the outside balcony.

A modern lobby with green and red seating, a patterned carpet, and artwork on the walls.

15. Room Mate Collection Giulia, Milan

Centro Storico, 0.4 km from San Sebastiano

Anna

HK$3,393

HK$3,908 total

includes taxes & fees

25 Oct - 26 Oct

A modern restaurant with glass tables and chairs, large windows, and a wooden floor.

A modern interior with a glass staircase, a wall with a digital art display, and a reception area.

A multi-story building with large windows, balconies with plants, and a modern glass structure on the upper floor.

A hotel room with a bed adorned with red rose petals, a modern yellow dining area, and a large mural of a cityscape.

16. The Street Milano Duomo | a Design Boutique Hotel

Centro Storico, 0.6 km from San Sebastiano

Jerry

HK$2,590

HK$3,025 total

includes taxes & fees

17 Nov - 18 Nov

A restaurant with checkered flooring, tables set with white tablecloths, and shelves with glassware.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

A hotel entrance with a glass door, a blue awning, and a red sofa visible inside.

A hotel room with a bed, a sofa, a chair, a small table, and a balcony with a view of buildings.

17. Speronari Suites

Centro Storico, 0.2 km from San Sebastiano

Christine

HK$2,287

HK$2,684 total

includes taxes & fees

25 Oct - 26 Oct

A spacious indoor dining area with multiple seating arrangements, including booths and tables, and is adorned with large chandeliers and potted plants.

A modern indoor pool area with a waterfall feature, lounge seating, and contemporary decor.

A dining table with a variety of dishes, a glass of wine, and a potted plant.

A historic building with ornate architecture, large windows, and a prominent dome.

18. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Centro Storico, 0.4 km from San Sebastiano

Laurel

HK$7,194

HK$8,124 total

includes taxes & fees

2 Nov - 3 Nov

A rooftop restaurant with outdoor seating overlooking a cityscape.

A buffet with various fruits, pastries, and desserts.

A tall building with a colorful facade, multiple windows, and a ground-level entrance with a shop named "The Square".

A modern hotel lobby with a reception desk, seating area, and large windows offering city views.

19. The Square Milano Duomo - Preferred Hotels & Resorts

Centro Storico, 0.3 km from San Sebastiano

Victor

HK$2,655

HK$3,096 total

includes taxes & fees

9 Nov - 10 Nov

A rooftop terrace with a view of a historic cathedral, furnished with outdoor seating and a large umbrella.

A modern bathroom with a large window, a bathtub, and a mirror.

A modern interior with a hanging chair, a bench, and a vase with flowers.

A modern hotel room with a large bed, a glass partition, a flat-screen TV, a small desk, and a view of the city.

20. Prestige Boutique Homes Aparthotel Piazza Duomo View

Centro Storico, 0.2 km from San Sebastiano

Shelmara

HK$1,829

HK$3,338 total

includes taxes & fees

29 Oct - 30 Oct

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Hotels recommended for families near San Sebastiano

A hotel with a modern facade, large windows, and a marquee sign.

A lobby with a checkered floor, a reception desk, and a seating area.

A restaurant with tables set for dining, a bar area with bottles, and a green carpeted floor.

A hotel lobby with a curved reception desk, marble columns, and a check-in counter.

Hotel Brunelleschi

Milan Centre

HK$1,551

HK$1,706 total

includes taxes & fees

22 Nov - 23 Nov

Hotel Spadari al Duomo True Stay

Milan Centre

HK$1,759

HK$2,111 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, two bedside tables, a desk with a chair, a television, and a window with curtains.

A dining table with two chairs, two wine glasses, and a candle on a table in a dimly lit room with vertical light fixtures.

A rooftop pool with lounge chairs, a view of a cathedral, and a green wall.

A conference room with rows of chairs, a projector screen, and a presentation area.

Sina De la Ville

Milan Centre

HK$1,788

HK$2,143 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a checkered floor, seating areas, a reception desk, and a large mirror.

A hotel room with a bed, a desk with a chair, a small table with a vase of flowers, a television mounted on the wall, and a window with curtains.

An outdoor patio with tables and chairs, surrounded by potted plants and a stone floor.

A spacious lobby with high ceilings, large columns, and a skylight.

Hotel Regina

Milan Centre

HK$1,597

HK$1,933 total

includes taxes & fees

23 Nov - 24 Nov

A rooftop terrace with a dining area, lounge chairs, and a view of a historic building.

The entrance to Rosa Grand with a man in uniform at the door.

A modern dining area with a round table set for six, surrounded by comfortable chairs. There are two pendant lights above the table, and the room has a large window with curtains.

A hotel room with a large bed, a TV, and a view of a cathedral.

Rosa Grand Milano - Starhotels Collezione

Milan Centre

HK$2,756

HK$3,208 total

includes taxes & fees

8 Nov - 9 Nov

Hotel Milano Castello

Milan Centre

HK$1,442

HK$1,709 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a city view, a glass coffee table, and a dining area with yellow chairs.

A hotel room with a large bed, a view of the cityscape, a round mirror, and a vase with flowers on a table.

A balcony with a wicker chair and a glass table holding a bowl of apples, overlooking a cityscape with historic architecture and modern buildings.

A modern hotel room with a large panoramic window, a marble floor, and a dining area with chairs and a table.

Uptown Palace

Milan Centre

HK$1,347

HK$1,658 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a sofa, a round table with fruit, two red chairs, and large windows with a city view.

A modern bar area with marble countertops, bar stools, and a checkered floor.

A modern lobby with a marble reception desk, a staircase, and a dining area with chairs and tables.

Tivoli President Milano Hotel

Milan Centre

HK$2,718

HK$3,200 total

includes taxes & fees

22 Nov - 23 Nov

Top San Sebastiano Hotel Reviews

Hotel Dei Cavalieri Milano Duomo

8/10 Good

"We stayed at this hotel on our last night in Italy, before flying home. We had stayed in six other hotels throughout the country and this was by far the largest room and bathroom of all of them. In fact the bathroom, with it's double sinks and large walk in shower, was big even by American standards. The beds were comfortable and the breakfast buffet had many choices of delicious foods. The only negative was that the walls seemed rather thin for a hotel as we were able to clearly hear a conversation in an adjoining room, which luckily didn't last very long and we were able to get to sleep for an early departure. Would recommend staying here for the size of the rooms and location to the Duomo."

Duomo Hotel & Apartments

8/10 Good

"Nice hotel with great location within 5 minute walk of Duomo plaza. Staff was friendly and professional. We were surprised by the noise levels in the room. Room was on the first floor facing the street and we heard late evening consistent noise from loud conversations on the street, and then the garage pickup trucks beginning just before 5am until 6:30am the first night. Second night we were awaken by very loud noises from the water lines - apparently due to showers taken in nearby rooms at 1am lasting for an hour. Our advice for those booking this place is to request a high floor and bring noise canceling headphones if you want a solid night’s sleep."

Milan Retreats Duomo

10/10 Excellent

"We had an amazing stay! The location is perfect—just a few minutes' walk to the Duomo in a wonderful neighborhood. The apartment was spacious and comfortable for the three of us, and everything was exactly as we hoped. Our host was incredibly friendly, quick to communicate, and checked in to make sure we had everything we needed. They provided timely check-in instructions and gave us fantastic local restaurant recommendations. We highly recommend this place and would love to stay again!"

Hotel Cavour

10/10 Excellent

"Cool furniture and lighting. Good location as near Berera and not too far from sights."

ibis Milano Centro

10/10 Excellent

"酒店管理很专业。景点和火车站基本在步行范围之内。Recommended."

Room Mate Collection Giulia, Milan

10/10 Excellent

"Amenities and location were amazing but what really made the place special was the staff. They were very very helpful and always friendly even during riots. Their suggestions were excellent . Would stay here again and would recommend. Concierge service in particular was amazing."

B&B HOTEL Milano Duomo Velasca

10/10 Excellent

"Incredible location, nice room, and the breakfast was great value. Very much recommended."

Hotel Berna

10/10 Excellent

"Very clean room! Excellent breakfast and staff! Thank you!"

Hotel Manin

10/10 Excellent

"Nice breakfast buffet"

Other attractions near San Sebastiano

Biblioteca Ambrosiana

10.0/10 (1 review)

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.

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Via Torino

During your visit to Milan, you can browse for the perfect souvenirs at Via Torino. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes.

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Chiesa di San Sepolcro

Chiesa di San Sepolcro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art galleries and stunning cathedral.

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Chiesa di Sant'Alessandro in Zebedia

Chiesa di Sant'Alessandro in Zebedia is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's shops or stunning cathedral to your travel plans.

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Chiesa Santa Maria Presso di San Satiro

9.0/10 (12 reviews)

Chiesa Santa Maria Presso di San Satiro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's stunning cathedral or shops to your travel plans.

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Museo Mangini Bonomi

You can study the exhibits at Museo Mangini Bonomi, a museum with a storied past, during your holiday in Milan. Experience the area's fascinating museums and acclaimed art galleries.

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Trezzo Live Club

You can make plans for a show at Trezzo Live Club on your trip to Milan. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes.

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Casa Ferrario

You can study the exhibits at Casa Ferrario, a museum with a storied past, during your trip to Milan. Discover the area's acclaimed art galleries and stunning cathedral.

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Frequently asked questions

What's the area like around San Sebastiano?

San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, take a look at the 1327 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near San Sebastiano?

Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a bar. Other good options within a short distance include The Square Milano Duomo - Preferred Hotels & Resorts and Uptown Palace.

How many hotels will I be able to find close to San Sebastiano?

Expedia has 1327 hotels and other accommodation options within a mile from San Sebastiano.

If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near San Sebastiano.

What can I see and do near San Sebastiano?

Castello Sforzesco, Pinacoteca di Brera and Leonardo da Vinci Museum of Science and Technology feature captivating exhibits. Sights like Cathedral of Milan, Milan Baptistery and Galleria Vittorio Emanuele II are must-sees while exploring the area. You can check out the local talent at Teatro Dal Verme, Teatro alla Scala and Teatro San Babila.

How can I get to San Sebastiano?

With so many choices for transport, seeing the area around San Sebastiano is easy. You can access metro transport at Duomo Station, Via Orefici P.za Cordusio Tram Stop and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.

Milan San Sebastiano Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for San Sebastiano hotels

1. Oriana Homèl Milano

2. AF Duomo - Milano Luxury Suites

3. Heart Milan Apartments - Duomo Colonne

4. Palazzo Fulcorina Apartments

5. Hotel Milano Castello

6. Ostello Bello Milano Duomo

7. Casa Brivio

8. Casa Laveni

9. Palazzo Touring Club Milan, A Radisson Collection Hotel

10. Hotel Spadari al Duomo True Stay

11. Park Hyatt Milano

12. Heart Milan Apartments - Duomo District

13. TheROOMS by TheFLOOR Collection

14. Palazzo Segreti

15. Room Mate Collection Giulia, Milan

16. The Street Milano Duomo | a Design Boutique Hotel

17. Speronari Suites

18. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

19. The Square Milano Duomo - Preferred Hotels & Resorts

20. Prestige Boutique Homes Aparthotel Piazza Duomo View

Hotels recommended for families near San Sebastiano

Hotel Brunelleschi

Hotel Spadari al Duomo True Stay

Sina De la Ville

Hotel Regina

Rosa Grand Milano - Starhotels Collezione

Hotel Milano Castello

Uptown Palace

Tivoli President Milano Hotel

Top San Sebastiano Hotel Reviews

Hotel Dei Cavalieri Milano Duomo

Duomo Hotel & Apartments

Milan Retreats Duomo

Hotel Cavour

ibis Milano Centro

Room Mate Collection Giulia, Milan

B&B HOTEL Milano Duomo Velasca

Hotel Berna

Hotel Manin

Other attractions near San Sebastiano

Biblioteca Ambrosiana

Via Torino

Chiesa di San Sepolcro

Chiesa di Sant'Alessandro in Zebedia

Chiesa Santa Maria Presso di San Satiro

Museo Mangini Bonomi

Trezzo Live Club

Casa Ferrario

Frequently asked questions