A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys 4 Stars Hotels

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Check availability on Florida Keys 4 Star Hotels

Tonight
22 Sept - 23 Sept
Tomorrow
23 Sept - 24 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Florida Keys 4-star hotels

A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A poolside area with blue chairs and a thatched-roof structure.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Susan
HK$1,561
HK$2,070 total
includes taxes & fees
1 Oct - 2 Oct
Reefhouse Resort & Marina
A wooden deck with a view of the ocean and a palm tree.
A coconut drink with a straw, a cherry, and a slice of fruit on a table by a pool with a waterfall and palm trees in the background.
A beach bar with a thatched roof, palm trees, and a view of the sea.
A modern hotel room with a large bed, a desk with a lamp, a chair, and a view of the ocean.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Milagros
HK$1,859
HK$2,524 total
includes taxes & fees
1 Oct - 2 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.
A resort pool with palm trees, beach chairs, and umbrellas.
An aerial view of a resort with a swimming pool, palm trees, and a dock.

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
MICHAEL
HK$1,213
HK$1,938 total
includes taxes & fees
24 Sept - 25 Sept
Amara Cay Resort
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A resort with a pool, beach, and ocean view.
A beach with palm trees, a clear blue sky, and a calm sea.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.

4. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
Canada
Eslita
HK$1,563
HK$2,332 total
includes taxes & fees
29 Sept - 30 Sept
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.
A pathway leading to a pool area with palm trees and a sunset view.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.

5. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Katherine
HK$1,455
HK$2,240 total
includes taxes & fees
28 Sept - 29 Sept
Hawks Cay Resort
An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Tania
HK$2,063
HK$2,754 total
includes taxes & fees
5 Oct - 6 Oct
Playa Largo Resort & Spa, Autograph Collection
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.
A bar area with a wooden counter, bar stools, and potted plants.
A paved pathway leading to a beach with palm trees and a view of the ocean.

7. Islander Resort

Islander Resort
Matecumbe
United States
John
HK$1,536
HK$2,257 total
includes taxes & fees
29 Sept - 30 Sept
Islander Resort
A swimming pool surrounded by palm trees and lounge chairs.
A beach scene with a wooden deck, palm trees, and a gazebo-like structure.
A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.
An aerial view of a resort with a central swimming pool, surrounded by lush greenery and palm trees, with a view of the ocean.

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
HK$1,437
HK$2,119 total
includes taxes & fees
19 Oct - 20 Oct
Tranquility Bay Beachfront Hotel and Resort
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A beach resort with palm trees, a thatched hut, and a purple building with a window.
A row of colorful beach huts with palm trees in the background.
A resort with a pool surrounded by palm trees and a view of the ocean.

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
La Siesta Resort & Villas
A marina with boats docked, a lighthouse, and a resort with outdoor seating.
A spacious lobby with a central round table, surrounded by wicker chairs, large potted plants, and decorative lanterns.
An outdoor dining area with tables and chairs, a pool, and a view of the sea and boats.
A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.

10. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
DANA
HK$1,152
HK$1,591 total
includes taxes & fees
11 Oct - 12 Oct
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A wooden deck with a pool and chairs overlooking a beach with palm trees.
A pool area with palm trees and a view of the ocean.
A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.
A bar area with stools, a counter, and hanging lanterns.

11. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
HK$1,373
HK$1,922 total
includes taxes & fees
21 Oct - 22 Oct
Grassy Flats Resort & Beach Club
A resort pool with palm trees and lounge chairs, surrounded by a beachfront.
An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.
A resort with a large pool surrounded by lounge chairs, a beach area, and a building with multiple floors.
A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.

12. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
HK$2,973
HK$3,830 total
includes taxes & fees
1 Oct - 2 Oct
Villas At Hawks Cay Resort
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
HK$3,248
HK$4,151 total
includes taxes & fees
1 Oct - 2 Oct
The Islands of Islamorada
A large hotel with a pool, multiple balconies, and palm trees.
A beach with clear water and gentle waves.
A beachside wedding setup with wicker chairs and a white canopy, palm trees, and a sunset view.
A large, two-story hotel with a swimming pool in front.

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina
A covered outdoor area with a wooden deck, white railings, and a view of the ocean.
A spacious dining area with a long table, wicker chairs, and hanging wicker lamps.
An aerial view of a coastal resort with multiple buildings, a marina, and clear blue waters.
A resort with multiple buildings, a large central pool, and a view of the ocean.

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
A modern kitchen with white cabinetry, a built-in oven, and a large island with stools.
A modern kitchen with a central island, bar stools, and a ceiling fan.
A beach with clear turquoise water, a wooden pier, and a rocky shoreline.

16. Florida Keys Getaway w/ Stunning Ocean Views

Florida Keys Getaway w/ Stunning Ocean Views
Long Key
Florida Keys Getaway w/ Stunning Ocean Views
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
HK$1,169
HK$1,889 total
24 Sept - 25 Sept
includes taxes & fees
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
HK$1,546
HK$2,206 total
29 Sept - 30 Sept
includes taxes & fees
Isla Bella Beach Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"What is unique about the property is how convenient and practical is the property, excellent for families! Always a nice experience"
Sonia 3-night trip
Posted 13 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Islander Resort

Islander Resort

10/10 Excellent
"Nice pool"
Henry 1-night trip
Posted 16 hours ago
Islander Resort
Hawks Cay Resort

Hawks Cay Resort

8/10 Good
"The village we were assigned has roaches and the main bedroom has the pain from the felling peeling which could be a hazard. Also, the water park that was supposed to be completed on September has a delay and that was the main reason a reserve this hotel."
Miladis 2-night trip
Posted 19 hours ago
Hawks Cay Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from HK$1,889
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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