A steel bridge with a sunset in the background.

Cairo hotels from HK$495

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (291 reviews)
"Breakfast was sparse. This motel needs a complete overhaul. "
United States
Susan
The price is HK$530
HK$588 total
includes taxes & fees
18 Jul - 19 Jul
Quality Inn Cairo I-57

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (420 reviews)
"Staff was excellent. It was fine for what it was — a cheap place near the highway"
United States
Emily
The price is HK$588
HK$652 total
includes taxes & fees
13 Jul - 14 Jul
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (647 reviews)
"Clean rooms,"
United States
Karl
The price is HK$466
HK$518 total
includes taxes & fees
19 Jul - 20 Jul
Super 8 by Wyndham Charleston/Sikeston East MO

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
The price is HK$423
HK$495 total
includes taxes & fees
13 Jul - 14 Jul
La Center Motel

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is HK$543
HK$603 total
includes taxes & fees
1 Aug - 2 Aug
Eagle Inn Charleston

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is HK$1,168
HK$2,277 total
includes taxes & fees
2 Aug - 3 Aug
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

A steel bridge with a sunset in the background.

Top Cairo Hotel Reviews

More cheap stays in Cairo

Find out more about Cairo

Top reasons to visit Cairo

  • Scenic Outdoor Adventures: Cairo, Illinois, offers beautiful campgrounds and recreational areas, perfect for nature enthusiasts.
  • Unique Riverboat Tours: Experience the stunning waterways of Cairo through captivating riverboat tours.
  • Rich Cultural Experience: Explore charming streets that showcase local culture and community spirit.
  • Historic Attractions: Visit nearby national parks and historic forts for a blend of natural beauty and cultural insights.
  • Comfortable Accommodation: Enjoy a variety of lodging options, catering to all types of travellers.

Find great hotels in and around Cairo

Discover a range of comfortable accommodation options in Cairo, Illinois, perfect for every traveller. Whether you're seeking pet-friendly hotels, family-oriented motels, or LGBTQIA welcoming inns, Cairo offers a variety of choices to ensure a delightful stay. With convenient amenities and a warm atmosphere, you'll find the ideal lodging to make your visit memorable.

  • Super 8 by Wyndham Charleston/Sikeston East MO: Conveniently located 16km from Cairo, Super 8 by Wyndham Charleston/Sikeston East MO offers a budget-friendly option that caters to families and pet owners alike. This motel features amenities designed with children in mind, such as complimentary cribs available by reservation. Additionally, the pet-friendly policy allows guests to bring their furry companions, with provisions for service animals and specific pet fees. The welcoming atmosphere makes it an ideal choice for those seeking a relaxed and accommodating stay.
  • The Riverstone Hotel Charleston-Sikeston: Situated 19km from Cairo, The Riverstone Hotel Charleston-Sikeston is tailored for budget-conscious travellers, particularly those on business trips or travelling with pets. This hotel allows dogs, with specific weight restrictions and fees applicable for pet stays. The property provides a comfortable environment with essential amenities for business travellers, ensuring a productive experience while also being pet-friendly, thus accommodating various travel needs.
  • Quality Inn Cairo I-57: Nestled in the heart of Cairo, the Quality Inn Cairo I-57 is a practical choice for families and pet owners seeking budget accommodation. The hotel offers complimentary cribs and first aid kits for added convenience. Pets are welcome, with a clear policy outlining cleaning fees and restrictions to ensure a pleasant environment for all guests. The combination of family-oriented amenities and a central location makes it a sensible option for those visiting the area.

Where to stay near Cairo

Cairo, Illinois, offers a unique blend of outdoor adventure and rich history, perfect for families and travellers alike. Explore the charming streets of Cairo, where you can experience local culture and community vibes. Nearby campgrounds provide a picturesque setting for relaxation and exploration. With its welcoming atmosphere and diverse activities, Cairo promises a delightful holiday experience for all visitors looking to discover this hidden gem in the United States.

  • Mound City: Located approximately 10km from Cairo, Mound City is a charming destination that invites visitors seeking outdoor adventures and romantic escapades. With a steady stream of travellers throughout the year, it peaks in popularity during March, July, and October. The city boasts a variety of recreational areas, parks, and golf facilities, making it an ideal spot for nature enthusiasts. Visitors can explore nearby forests and lakes, or relax in the urban park, all of which contribute to Mound City's allure as a serene getaway.
  • Charleston: Situated 18km away from Cairo, Charleston is a vibrant city known for its scenic beauty and adventurous spirit. It attracts visitors year-round, with peak travel times in April and June to July. Charleston offers a mix of recreational activities, shopping centres, and entertainment arenas, making it a lively hub for tourists. Notable attractions include the nearby national state park, picturesque lakes, and historic sites that provide a glimpse into the area’s rich heritage. Charleston is perfect for those looking to savour the outdoors while enjoying urban amenities.
  • Wickliffe: Just 10km from Cairo, Wickliffe is a delightful city that captures the essence of outdoor adventures and romantic experiences. Although visitor numbers remain steady throughout the year, the peak seasons are in March to April and August. Wickliffe features various recreational areas and golf courses, appealing to sports enthusiasts and nature lovers alike. Surrounded by beautiful lakes and nestled near a national state park and forests, Wickliffe offers ample opportunities for exploration and relaxation, making it a must-visit on your travel itinerary.

Things to do in Cairo

Shopping

Cairo offers a unique shopping experience with local shops and boutiques. For a broader selection, if you're up for a drive, visit the Cape Girardeau Mall, about 40km away, where you can find various national retailers and dining options.

Recreation

Cairo's Riverfront Park offers a tranquil setting along the Mississippi River, perfect for leisurely strolls and picnics. For relaxation, visit a local wellness spa that provides rejuvenating treatments and massages, allowing you to unwind and recharge amidst the scenic beauty of the area.

Adventure

In Cairo, explore the scenic trails along the Mississippi River, offering picturesque views and opportunities for birdwatching. Experience the thrill of kayaking on the river, immersing yourself in the natural beauty and tranquillity of the surroundings. Don’t miss the chance to visit local parks for hiking and picnicking.

Nightlife

Cairo offers a relaxed nightlife with venues like The Riverfront, where you can enjoy scenic views while sipping drinks. For a casual evening, visit local bars along the Main Street, often featuring live music and a friendly atmosphere perfect for unwinding after a day of exploration.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Cairo

To save money during your visit to Cairo, Illinois, consider travelling between November and January when accommodation prices are generally lower. Tuesdays are the cheapest days to stay, while Saturdays tend to be pricier. Utilise Expedia’s search tool to filter options by budget and location, and look for package deals that combine flights, hotels, and activities for added savings. Additionally, explore free local attractions and utilise public transport for an economical way to get around. Keep an eye out for app deals to maximise your budget during your stay.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to May and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, including your budget, desired location, and the type of accommodation you wish to stay in. To discover the most affordable prices and offers, simply adjust the price filter to sort from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel booking in Cairo with your flights and activities through an Expedia package.

Find the best attractions in and around Cairo

Cairo, Illinois, is an ideal destination for outdoor enthusiasts and adventure seekers, boasting stunning scenery and rich culture. Visitors can explore a variety of attractions, including national parks, nature reserves, and historic forts, each offering unique experiences that cater to those yearning for both natural beauty and cultural insights. This charming town promises memorable adventures and picturesque views for every traveller.

  • Columbus-Belmont State Park: Nestled 27km from Cairo, this park offers stunning outdoor scenery and various adventure activities. Explore the historic significance of the site, which played a key role during the Civil War, while enjoying its picturesque landscapes and hiking trails.
  • Fort Defiance State Park: Located within Cairo, this historic fort is a fascinating site filled with cultural significance. Visitors can learn about its strategic importance and enjoy the natural beauty surrounding the area, making it an enriching experience for history enthusiasts.
  • Ballard Wildlife Management Area: Situated 8km from Cairo, this wildlife preserve offers a blend of historical context and budget-friendly exploration. Enjoy birdwatching and hiking while appreciating the region’s natural habitats and rich history.

Best time to go to Cairo

The best time to visit Cairo can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Cairo falls in July, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Cairo falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighSlightly High
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

Reaching Cairo, Illinois, is convenient with several nearby airports. Cape Girardeau Municipal Airport (CGI) is situated 42km away, with nearby hotels such as Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both approximately 10km from the airport. Barkley Regional Airport (PAH) in Paducah, Kentucky, is 37km from Cairo, offering options like The Respite Bed and Breakfast, located 14km from the airport. For those considering Veterans Airport of Southern Illinois (MWA), which is 84km away, the Drury Inn & Suites Marion provides accommodation just 3km from the airport, ensuring easy access for visitors.

Frequently asked questions

Where is the best place for a stay in Cairo?
Based on our traveller data, Quality Inn Cairo I-57 is one of the top choices for your stay. This hotel offers free breakfast and free parking. Two other choices for your stay in the area are Super 8 by Wyndham Charleston/Sikeston East MO and The Riverstone Hotel Charleston-Sikeston. See all available top hotels, or vacation rentals in Cairo.
What are some of the best holiday rentals that Cairo has to offer?
Wandering the wineries or hitting the hills? We got you! Come stay!: This holiday home rental outside of Cairo is located in a rural location, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Cairo.
If I need to cancel my hotel reservation in Cairo, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Cairo.
What is staying in Cairo like?
Visitors can enjoy all that Cairo has to offer, including the restaurants, entertainment choices and riverfront. This city also attracts tourists with its small-town vibe. There are 28 hotels and other accommodation options in the surrounding area. Find out more about Cairo.
What should I do while I'm visiting Cairo?
The picturesque setting of Mississippi River and Ohio River Valley exemplify the area's natural beauty. Additionally, you might want to add Fort Defiance State Park to your itinerary. Take a look at what more there is to see and do in Expedia's Cairo guide.
What's the seasonal weather like in Cairo?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cairo is 1540 mm.

Explore a world of travel with Expedia