Best Southwest Illinois Hotels in 2026 from HK$475 - Fully Refundable Options

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Our top choices for Southwest Illinois hotels

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.

A compact kitchenette with a refrigerator and an ice dispenser.

A hotel room with two beds, a desk, and a window with a view.

1. Best Western U. S. Inn

Nashville

troy

HK$942

HK$1,026 total

includes taxes & fees

5 Oct - 6 Oct

A hotel room with a bed, a desk, a television, and a cityscape mirror.

A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.

A conference room with a TV, a door, and a window with blinds.

A reception area with a counter, framed certificates, a clock, and a checkered floor.

2. Super 8 by Wyndham Okawville

Okawville

Peter

HK$474

HK$502 total

includes taxes & fees

19 Oct - 20 Oct

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

A spacious lobby with a large seating area, a reception desk, and a television.

A hotel room with two beds, a large window with curtains, a wall-mounted lamp, and a patterned carpet.

3. Best Western Plus Centralia Hotel & Suites

Centralia

Jeremy

HK$1,091

HK$1,221 total

includes taxes & fees

5 Oct - 6 Oct

An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A lobby with patterned sofas, a fireplace, and framed pictures on the wall.

A modern hotel lobby with seating areas, including sofas and chairs, and a large window with blinds.

4. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

KEVIN

HK$800

HK$928 total

includes taxes & fees

11 Oct - 12 Oct

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

A buffet with labeled food options including turkey sausage and bacon.

A hotel room with two beds, a large window, and a wall-mounted lamp.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a window providing natural light.

5. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

John

HK$871

HK$982 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with tables and chairs, a brick building, and a parking lot in the background.

A modern living room with a fireplace, comfortable seating, and a television.

A reception area with a wooden reception desk, a wall-mounted decorative piece, and a vending machine.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a view of the outdoors.

6. Fairfield Inn & Suites by Marriott O'Fallon, IL

O'Fallon

Mohamad

HK$1,087

HK$1,250 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with a fire feature, cushioned seating, and a bar area.

An indoor swimming pool with clear water, marked depth lines, and a 'No Diving' sign.

A hotel reception area with a wooden reception desk, a minibar, and a refrigerator stocked with beverages and snacks.

A modern self-service breakfast area with a refrigerated drink dispenser, a variety of beverages, and a selection of fruits and pastries.

7. TownePlace Suites by Marriott St. Louis O'Fallon

O'Fallon

John

HK$1,099

HK$1,274 total

includes taxes & fees

25 Oct - 26 Oct

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

A snack and treat section with shelves stocked with various snacks, a 'Welcome to our store' sign, and a 'Treats' sign.

A reception desk with a "Welcome to the Prairie State" sign, a receptionist, and a digital display.

A modern kitchen with a coffee station, fruit display, and a waffle advertisement.

8. Hampton Inn O'Fallon

O'Fallon

Edmond

HK$862

HK$1,000 total

includes taxes & fees

11 Oct - 12 Oct

A hotel lobby with a reception desk, seating area, and a large screen TV.

A hotel room with a marble bathtub, a wooden dining table with chairs, a bed with a headboard, and a nightstand with lamps.

A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

A Comfort Suites hotel with a spacious parking lot and a modern brick facade.

9. Comfort Suites Mount Vernon

Mount Vernon

Lori

HK$960

HK$1,081 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

A hotel with a flat facade, multiple windows, and a sign indicating it is a 'SureStay Hotel by Best Western'.

A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

10. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

MARK

HK$671

HK$745 total

includes taxes & fees

5 Oct - 6 Oct

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and landscaped gardens.

A modern kitchen with a central island, bar stools, and various appliances.

A golf course with a flagstick, trees, and a water hazard.

A hotel room with a bed, bedside table, lamp, desk, chair, and a television.

11. Comfort Inn & Suites Marion I-57

Marion

Daniel

HK$807

HK$968 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A hotel reception area with a wooden reception desk, a digital kiosk, and a refrigerated display case with beverages.

A hotel with a covered entrance, outdoor seating, and a flag.

A spacious lobby with a central seating area, a large window, and a reception desk.

12. Home2 Suites by Hilton Carbondale

Carbondale

Alyssa

HK$828

HK$951 total

includes taxes & fees

1 Nov - 2 Nov

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

A spacious lobby with a stone reception desk, leather seating, and a large window offering a view of the outdoors.

A spacious lobby with a modern design, featuring a large seating area with leather chairs, a kitchen area with a counter and appliances, and a flat-screen TV mounted on the wall.

A hotel room with a large bed, a desk with a chair, a sofa, and a TV.

13. Best Western Plus MidAmerica Hotel

Mascoutah

Danny

HK$825

HK$940 total

includes taxes & fees

11 Oct - 12 Oct

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

14. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Susan

HK$871

HK$982 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a large flat-screen TV, a desk with drawers, a bench, and a wardrobe.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

A hot tub area with a view of the parking lot through a glass door.

A compact hotel room with a kitchenette, a blue sofa, a small wooden table, and a wooden floor.

15. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Jeremy

HK$863

HK$958 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

A Fairfield Inn & Suites by Marriott hotel with a parking lot and a clear sky.

A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

A hotel room with a large bathtub, a desk with a chair, and a bed.

16. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Mount Vernon

Susan

HK$787

HK$889 total

includes taxes & fees

17 Oct - 18 Oct

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.

A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

17. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Kenneth

HK$1,004

HK$1,129 total

includes taxes & fees

8 Oct - 9 Oct

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

A modern living room with a sofa, coffee table, and a dining area with chairs.

An indoor swimming pool with clear water, surrounded by white lounge chairs and tables, with a high ceiling and natural light from windows.

A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.

18. Country Inn & Suites by Radisson, Marion, IL

Marion

Lisa

HK$703

HK$843 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.

A reception area with a desk, chairs, a red carpet, and a television mounted on the wall.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

19. Quality Inn Mount Vernon, IL

Mount Vernon

Matthew

HK$565

HK$643 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a television, a desk, and a chair.

A reception area with a reception desk, a computer, a sewing machine, and an exit sign.

A laundry area with three washing machines and a dryer.

20. Super 8 by Wyndham Greenville

Greenville

Rebecca

HK$494

HK$549 total

includes taxes & fees

5 Oct - 6 Oct

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Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

O'Fallon Family Sports Park

8.6/10 (137 reviews)

Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Visit the shops and top-notch restaurants in this family-friendly area.

See properties

DuQuoin State Fairgrounds

8.2/10 (95 reviews)

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois

A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites Marion

10/10 Excellent

"Great stay! Lots of free food!"

Drury Inn & Suites St. Louis Collinsville

10/10 Excellent

"For our needs perfectly, we’ll be back"

Radisson Hotel Fairview Heights - St. Louis

10/10 Excellent

"Clean room and friendly staff. No hassle check in or out"

Walker's Bluff Casino Resort

10/10 Excellent

"Always a fun and great experience at Walker Bluff. Super clean rooms and staff are very friendly."

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Great staff and clean room"

Motel 6 Caseyville, IL - Caseyville Il

8/10 Good

"Room was clean, bed was comfortable, water pressure in the shower was more like a waterfall, and the smart TV wasn't smart 😕.... I stay here frequently and the staff is always very nice, so I didn't mind."

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."

Best Western St. Louis Fairview Heights

8/10 Good

"Hotel is remodeling for a fresh new look Rooms were nice. Hot breakfast. Close to restaurants and shopping."

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent

"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

552 Ramada Blvd Collinsville IL

HK$413

HK$475 total

11 Oct - 12 Oct

includes taxes & fees

Super 8 by Wyndham Collinsville St. Louis

2 Gateway Dr Collinsville IL

HK$416

HK$478 total

5 Oct - 6 Oct

includes taxes & fees

7/10 Good! (1,000 reviews)

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL

HK$417

HK$479 total

7 Oct - 8 Oct

includes taxes & fees

Best Western St. Louis Fairview Heights

150 Ludwig Dr Fairview Heights IL

HK$627

HK$708 total

1 Nov - 2 Nov

includes taxes & fees

7.4/10 Good! (124 reviews)

Baymont by Wyndham Marion

2608 W Main St Marion IL

HK$671

HK$805 total

1 Nov - 2 Nov

includes taxes & fees

Comfort Inn Edwardsville - St. Louis

3080 S State Route 157 Edwardsville IL

HK$747

HK$859 total

25 Oct - 26 Oct

includes taxes & fees

8.4/10 Very good! (956 reviews)

Hotels in Southwest Illinois with star-rating

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Southwest Illinois hotels from HK$475

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southwest Illinois

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Southwest Illinois hotels

1. Best Western U. S. Inn

2. Super 8 by Wyndham Okawville

3. Best Western Plus Centralia Hotel & Suites

4. Drury Inn & Suites St. Louis O'Fallon, IL

5. Holiday Inn Express & Suites Mount Vernon by IHG

6. Fairfield Inn & Suites by Marriott O'Fallon, IL

7. TownePlace Suites by Marriott St. Louis O'Fallon

8. Hampton Inn O'Fallon

9. Comfort Suites Mount Vernon

10. SureStay Hotel by Best Western Whittington Rend Lake

11. Comfort Inn & Suites Marion I-57

12. Home2 Suites by Hilton Carbondale

13. Best Western Plus MidAmerica Hotel

14. Drury Plaza Hotel Mt. Vernon

15. Holiday Inn Express Hotel & Suites Sparta by IHG

16. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

17. DoubleTree by Hilton Mt. Vernon

18. Country Inn & Suites by Radisson, Marion, IL

19. Quality Inn Mount Vernon, IL

20. Super 8 by Wyndham Greenville

Stay near popular Southwest Illinois attractions

World Wide Technology Raceway

O'Fallon Family Sports Park

DuQuoin State Fairgrounds

Learn more about Southwest Illinois

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites St. Louis Collinsville

Radisson Hotel Fairview Heights - St. Louis

Walker's Bluff Casino Resort

Drury Inn & Suites St. Louis O'Fallon, IL

Motel 6 Caseyville, IL - Caseyville Il

Comfort Inn Edwardsville - St. Louis

Best Western St. Louis Fairview Heights

Country Inn & Suites by Radisson, Marion, IL

More cheap stays in Southwest Illinois

Americas Best Value Inn Collinsville St. Louis

Super 8 by Wyndham Collinsville St. Louis

Super 8 by Wyndham O'Fallon

Best Western St. Louis Fairview Heights

Baymont by Wyndham Marion

Comfort Inn Edwardsville - St. Louis

Hotels in Southwest Illinois with star-rating

Explore a world of travel with Expedia

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