Cheap Flights from San Francisco (SFO) to Santiago (SCL) from HK$3,250~

View HK$3,250 flight on Wed, 29 Oct 2025Opens in a new window

Popular airlines from San Francisco Intl. Airport (SFO) to Santiago Intl. Airport (SCL)

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Find Cheap Flights from San Francisco (SFO) to Santiago (SCL)

Prices were available within the past 7 days and start at HK$3,250 for one-way flights and HK$5,503 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$5,503 Return, found 3 days ago
HK$5,503
Return
found 3 days ago
Select Delta flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$5,503 found 3 days ago
Delta
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,243 Return, found 3 days ago
HK$6,243
Return
found 3 days ago
Select Delta flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,243 found 3 days ago
Copa
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,327 Return, found 3 days ago
HK$6,327
Return
found 3 days ago
Select Copa flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,327 found 3 days ago
LATAM Airlines Group
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,395 Return, found 3 days ago
HK$6,395
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,395 found 3 days ago
Copa
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,717 Return, found 3 days ago
HK$6,717
Return
found 3 days ago
Select Copa flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,717 found 3 days ago
Delta
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,723 Return, found 3 days ago
HK$6,723
Return
found 3 days ago
Select Delta flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,723 found 3 days ago
United
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,753 Return, found 3 days ago
HK$6,753
Return
found 3 days ago
Select United flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,753 found 3 days ago
American Airlines
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,753 Return, found 3 days ago
HK$6,753
Return
found 3 days ago
Select American Airlines flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,753 found 3 days ago
LATAM Airlines Group
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,759 Return, found 3 days ago
HK$6,759
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,759 found 3 days ago
LATAM Airlines Group
Wed, 29 Oct - Sun, 2 Nov
SFO
San Francisco
SCL
Santiago
HK$6,803 Return, found 3 days ago
HK$6,803
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Wed, 29 Oct from San Francisco to Santiago, returning Sun, 2 Nov, priced at HK$6,803 found 3 days ago

Find the cheapest month to fly from San Francisco (SFO) to Santiago (SCL)

November is typically the cheapest month to fly

From HK$4,533 - HK$6,927 per traveller.

Graph displaying average flight prices per month

San Francisco to Santiago route information
Origin airport
San Francisco Intl.
Destination airport
Arturo Merino Benitez
Return price
HK$5,503
Distance
9474 km

Flights from San Francisco to Santiago

Book cheap flights from San Francisco (SFO) to Santiago (SCL) on Expedia.com.hk. Find the best flight deals to destinations around the world for your next leisure or business travel on Expedia.com.hk.

Search for flights from San Francisco (SFO) to Santiago (SCL) to find great flight deals suitable to your travel date and time. Expedia.com.hk flight booking search engine is simple to use and looking for cheap flights is as easy as a click of a mouse or on your mobile devices.

Be assured that you’re seeing the best price guaranteed! Our friendly customer service representatives are here to serve you 24 hours day to provide assistance and answer any questions that you may have about booking your San Francisco (SFO) to Santiago (SCL) trip. Call us at 3077-4857 (direct number - 24 hours day for English).

Save more when combine your Santiago flight with a hotel for a package deal! Discover additional savings by booking in advance. Now you can find activities in Santiago and things to do in Santiago for your perfect vacation with Expedia Thing to Do.

If you would like to book flights to Santiago more flexibly, many prefer to purchase one-way tickets with options to take different airlines. A one way ticket to Santiago is HK$3,250 now!

 

Frequently asked questions

How much is a flight from San Francisco Intl. Airport (SFO) to SCL?
Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip flight between San Francisco Intl. Airport (SFO) and Nuevo Pudahuel Airport was HK$5,503. Cheap tickets don't hang around forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Santiago International Airport?
Every air carrier has its own set of terms and conditions. If you do decide to cancel, follow the simple instructions on our Customer Service Portal.
How do I find cheap flights from San Francisco Airport to Santiago International Airport that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for San Francisco Airport to Nuevo Pudahuel Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from SFO to Santiago International Airport?
The distance is around 9,500 kilometers, so pack your carry-on bag with everything you need to make your journey comfortable. Not sure what to take on board your San Francisco to Santiago flight? A sleep mask, earplugs and a travel pillow are among the essentials.
Which airlines fly direct from SFO to SCL?
Unfortunately, there are no airlines that fly directly between SFO and Santiago International Airport. You'll have to book a flight with one or more stops.
Are San Francisco Airport to Arturo Merino Benitez Airport (SCL) flight tickets cheaper when they're purchased at the last minute?
Late planners can occasionally find a bargain, with some super cheap fares from SFO to Santiago International Airport emerging a few weeks prior to the departure date. If you'd rather plan ahead of time, Expedia compares and updates the best flight deals continuously — as early as 12 months in advance in some cases. It does depend on the carrier though, as not all airlines publish prices that far in advance.

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