A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys 4 Stars Hotels

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Check availability on Florida Keys 4 Star Hotels

Tonight
14 Aug - 15 Aug
Tomorrow
15 Aug - 16 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Our top choices for Florida Keys 4-star hotels

1. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Craig
HK$1,519
HK$2,312 total
includes taxes & fees
25 Aug - 26 Aug
Hawks Cay Resort

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Jennifer
HK$1,988
HK$2,669 total
includes taxes & fees
27 Aug - 28 Aug
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Estefani
HK$1,319
HK$2,058 total
includes taxes & fees
19 Aug - 20 Aug
Amara Cay Resort

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Matt
HK$1,718
HK$2,247 total
includes taxes & fees
19 Aug - 20 Aug
Reefhouse Resort & Marina

5. Islander Resort

Islander Resort
Matecumbe
United States
Chris
HK$1,821
HK$2,578 total
includes taxes & fees
17 Aug - 18 Aug
Islander Resort

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Nicole
HK$1,875
HK$2,542 total
includes taxes & fees
30 Aug - 31 Aug
Playa Largo Resort & Spa, Autograph Collection

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Ana
HK$1,626
HK$2,403 total
includes taxes & fees
7 Sept - 8 Sept
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United States
Barbara
HK$1,626
HK$2,333 total
includes taxes & fees
13 Sept - 14 Sept
Tranquility Bay Beachfront Hotel and Resort

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United Kingdom
joanne
HK$1,473
HK$1,953 total
includes taxes & fees
3 Sept - 4 Sept
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
HK$1,213
HK$1,938 total
includes taxes & fees
20 Aug - 21 Aug
La Siesta Resort & Villas

11. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Elise
HK$6,081
HK$7,327 total
includes taxes & fees
15 Aug - 16 Aug
Villas At Hawks Cay Resort

12. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United Kingdom
Katherine
HK$1,019
HK$1,523 total
includes taxes & fees
21 Aug - 22 Aug
Grassy Flats Resort & Beach Club

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
HK$2,825
HK$3,667 total
includes taxes & fees
25 Aug - 26 Aug
The Islands of Islamorada

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
HK$1,169
HK$1,889 total
25 Aug - 26 Aug
includes taxes & fees
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
HK$1,595
HK$2,263 total
13 Sept - 14 Sept
includes taxes & fees
Isla Bella Beach Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Hawks Cay Resort

Hawks Cay Resort

8/10 Good
"The beauty of the resort takes you away, and reminds you that this is paradise."
Craig 5-night trip
Posted 1 day ago
Hawks Cay Resort
Islander Resort

Islander Resort

10/10 Excellent
"Gran limpieza. Personal atento y profesional . Fantástico lugar para descansar."
Guillermo 2-night trip
Posted 2 days ago
Islander Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent
"awesome resort in Marathon, beach, pool and all the resort has to offer. Great location"
Barbara 3-night trip
Posted 2 days ago
Tranquility Bay Beachfront Hotel and Resort

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from HK$1,889
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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