Hotels in Alexander County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in Alexander County

Cairo Ohio River Bridge traversing over the Ohio River at sunset
HotelsHotels

Cairo

Cairo

Check prices for these dates

Next weekend
29 May - 31 May
In two weeks
5 Jun - 7 Jun

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Alexander County hotels

Smart TV

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (27 reviews)
"The place was quiet, clean and secluded. Exactly what my wife and I were looking for. Thanks for having us!"
United States
Andy I.
The price is HK$862
HK$1,420 total
includes taxes & fees
27 May - 28 May
Peaceful secluded cabin located near Horseshoe Lake
Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is HK$587
HK$651 total
includes taxes & fees
21 Jun - 22 Jun
Quality Inn Cairo I-57
Dining

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (39 reviews)
"Peaceful and suited our needs perfectly."
United States
Matthew
The price is HK$881
HK$1,100 total
includes taxes & fees
2 Jun - 3 Jun
Cozy cabins on beautiful Horseshoe Lake
Exterior

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"It’s very nice and comfortable "
United States
John S.
The price is HK$881
HK$1,100 total
includes taxes & fees
26 May - 27 May
The Rested Duck Mallard Room
Interior

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (9 reviews)
"We had an absolutely perfect stay in Jonesboro. Will be back anytime we come hunt the area!"
United States
Sarah W.
The price is HK$909
HK$2,034 total
includes taxes & fees
5 Jun - 6 Jun
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Property grounds

Wandering the wineries or hitting the hills? We got you! Come stay!

Wandering the wineries or hitting the hills? We got you! Come stay!
Tamms
10.0 out of 10, Exceptional, (29 reviews)
"Great place to stay for our hunting trip. Host was helpful and very accommodating."
United States
John F.
Wandering the wineries or hitting the hills? We got you! Come stay!
Terrace/patio

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit
Jonesboro
10.0 out of 10, Exceptional, (57 reviews)
"Was a very nice place to stay. Interestingly decorated. My wife and I had a relaxing stay. "
United States
Steve W.
Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit
Outdoor spa tub

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest

Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (282 reviews)
"Cabin was exactly as described. A perfect 3 night getaway. Hosts are fantastic!"
United States
Susan
Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest
Terrace/patio

Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks
Jonesboro
10.0 out of 10, Exceptional, (3 reviews)
"Very friendly hosts. Met them and they were a pleasure to interact with. They had one of the most complete array of amenities that we have ever encountered in our trips! We did have some issues with losing TV service on our last night, but I imagine that it was not their fault.All in all a pleasant experience."
United States
Timothy S.
Nanny's Place- Cozy Porchview Getaway B&B by Shawnee Hills Wine Trail and Parks
Private kitchen

Fabulous cabin with AC in charming Tamms

Fabulous cabin with AC in charming Tamms
Tamms
6.0 out of 10, (1 review)
Fabulous cabin with AC in charming Tamms
Smart TV, fireplace

Outdoorsman Paradise

Outdoorsman Paradise
Wolf Lake
10.0 out of 10, Exceptional, (12 reviews)
"Very nice, comfortable property. Great place for R&R!"
United States
Cheri C.
Outdoorsman Paradise
Terrace/patio

Beautiful Cabin Retreat

Beautiful Cabin Retreat
tamms
8.2 out of 10, Very good, (41 reviews)
"This is a very nice, peaceful cabin. The host was very friendly and accommodating. I would definitely stay here again."
United States
Anonymous traveller
The price is HK$1,058
HK$1,744 total
includes taxes & fees
31 May - 1 Jun
Beautiful Cabin Retreat
Fridge, microwave, oven, stovetop

Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks
Jonesboro
10.0 out of 10, Exceptional, (1 review)
"Property is super cute. Check in was easy. Host communicated very quickly. Had everything you would need to stay for an extended period of time. Delicious zucchini bread provided for breakfast. Easy to find. Would definitely stay here again if we are ever back in Southern Illinois."
United States
Mandy H.
Nanny's Place- Cozy Rustic Getaway B&B by Shawnee Hills Wine Trail and Parks
Fridge, microwave, oven, stovetop

Nanny's Place-Cozy Entire Home Getaway B&B by Shawnee Hills Wine Trail and Parks

Nanny's Place-Cozy Entire Home Getaway B&B by Shawnee Hills Wine Trail and Parks
Jonesboro
Nanny's Place-Cozy Entire Home Getaway B&B by Shawnee Hills Wine Trail and Parks
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (635 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is HK$480
HK$532 total
includes taxes & fees
14 Jun - 15 Jun
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is HK$548
HK$609 total
includes taxes & fees
28 May - 29 May
The Riverstone Hotel Charleston-Sikeston
View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is HK$560
HK$622 total
includes taxes & fees
1 Jun - 2 Jun
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Alexander County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"We appreciated the evening food/drinks and the breakfast food. It saved us a ton of money having to feed 4 grand kids. The staff was exceptional! It was our second visit to this property. We highly recommend it."
Tammy 1-night trip
Posted 1 hour ago
Drury Plaza Hotel Cape Girardeau Conference Center

Explore a world of travel with Expedia