Best Depew Hotels in 2026 from HK$490 - Fully Refundable Options

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Pet friendly

Pool

Apartment

Hot tub

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Waterpark

Cottage

Condo

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Our top choices for Depew hotels

A pool area with a hot tub, lounge chairs, and a lifeguard chair.

A modern hotel lobby with a central bar area, seating arrangements, and pendant lighting.

A modern dining area with a round table, two chairs, and a pendant light.

1. Fairfield Inn & Suites by Marriott Buffalo Airport

Buffalo

Lisa

HK$1,087

HK$1,270 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with clear water, lounge chairs, and a lifeguard stand.

A modern hotel lobby with a blue accent wall, a reception desk, a sofa, a chair, and a coffee table.

A gym with a bench, dumbbells, and a treadmill.

A hotel room with a bed, a desk, a chair, a sofa, a small round table, and a TV mounted on the wall.

2. Comfort Inn & Suites Buffalo Airport

Buffalo

Sarah

HK$876

HK$996 total

includes taxes & fees

30 Sept - 1 Oct

A hotel pool area with a hot tub, lounge chairs, and a seating area with tables.

A spacious hotel lounge with multiple seating areas, a flat-screen TV, and a large window providing natural light.

A modern bar area with a central island, bar stools, and a menu display.

An outdoor patio area with a stone fire pit surrounded by wicker furniture and cushions.

3. Courtyard Buffalo Airport

Buffalo

Tracy

HK$1,294

HK$1,510 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, desk, and a large mirror with built-in lighting.

A lobby area with a vending machine, snack shelves, seating, and a reception desk.

A gym with treadmills, exercise bikes, and a mirrored wall.

A Holiday Inn Express hotel with a prominent entrance and a clear blue sky.

4. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Buffalo

Nadine

HK$910

HK$1,035 total

includes taxes & fees

21 Oct - 22 Oct

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

A modern indoor space with a foosball table, seating areas, a mural, and a television screen.

A modern lounge area with seating, tables, and hanging chairs.

5. Tru by Hilton Williamsville Buffalo Airport

Buffalo

Lachelle

HK$1,060

HK$1,206 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, a sofa, a desk with a chair, a television, and a minibar.

A spacious dining area with multiple wooden tables and chairs, a kitchen area with a counter and appliances, and a tiled ceiling with a grid pattern.

A spacious lobby with a staircase, a reception desk, and a vending machine.

A Sleep Inn & Suites hotel with a modern design, featuring a prominent entrance, a covered walkway, and a well-maintained lawn.

6. Sleep Inn & Suites Buffalo Airport

Buffalo

SUSANNA

HK$551

HK$626 total

includes taxes & fees

20 Oct - 21 Oct

A bar area with multiple stools, a counter, and TVs displaying sports.

A hotel room with a bed, a desk, a television, and a couch.

A gym with treadmills, elliptical machines, and weightlifting equipment.

A hotel room with a beige sofa, a wooden coffee table, a TV, and a bed with a wooden headboard.

7. Buffalo Airport Hotel

Buffalo

Patricia

HK$716

HK$814 total

includes taxes & fees

23 Sept - 24 Sept

A patio area with a fire pit, outdoor furniture, and a pergola.

A multi-story hotel with a prominent entrance, well-maintained landscaping, and a clear view of the hotel's name.

A modern hotel lobby with a fireplace, seating area, and a 'Suite Shop' with refrigerated display cases.

An indoor swimming pool with lounge chairs and umbrellas, surrounded by walls with windows and doors.

8. Homewood Suites by Hilton Buffalo Airport

Buffalo

Rebeca

HK$1,023

HK$1,194 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a central seating area, a shop in the background, and potted plants along the walkway.

An outdoor patio with a fire pit, seating, and string lights.

A large indoor swimming pool with clear blue water, surrounded by white pillars and blue-tiled edges.

A modern bar area with a long counter, multiple seating options, and a unique ceiling design.

9. Hilton Garden Inn Buffalo Airport

Buffalo

Randol

HK$1,280

HK$1,495 total

includes taxes & fees

18 Oct - 19 Oct

A hotel lobby with a bar area, seating arrangements, and large windows providing natural light.

A hotel reception desk with a 'Welcome to Buffalo' sign, framed pictures on the wall, and a 'Hilton Honors' sign.

A snack bar with refrigerated drinks, chips, and cookies.

An indoor swimming pool with clear water, a tiled edge, and a pool ladder. There are lounge chairs and tables around the pool area.

10. Hampton Inn & Suites Buffalo Airport

Buffalo

Carmen

HK$1,023

HK$1,194 total

includes taxes & fees

18 Oct - 19 Oct

A pool area with clear blue water, a diving board, and several lounge chairs.

A hotel with a modern design, featuring a prominent sign for TownePlace Suites by Marriott.

A modern hotel lobby with a kitchen area, a seating area, and a refrigerator stocked with beverages.

A modern conference room with tables and chairs, large windows, and a carpeted floor.

11. TownePlace Suites Buffalo Airport

Buffalo

Thein

HK$1,299

HK$1,517 total

includes taxes & fees

18 Oct - 19 Oct

A hotel with a prominent sign reading "HOME 2 HOME" and a covered parking area.

A modern indoor seating area with tables and chairs, a sofa with cushions, and hanging pendant lights.

An indoor swimming pool with tiled flooring, seating areas, and potted plants.

12. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

Tammy

HK$1,363

HK$1,591 total

includes taxes & fees

11 Oct - 12 Oct

A buffet setup with various food items and utensils.

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

13. Salvatores Grand Hotel

Buffalo

Carol

HK$1,326

HK$1,508 total

includes taxes & fees

5 Oct - 6 Oct

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A multi-story hotel with a stone facade, a prominent entrance with a metal archway, and a parking lot in front.

A hotel room with two beds, a desk, a chair, a coffee machine, and a large window with curtains.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

14. The Delavan Hotel & Spa

Bowmansville

Peter

HK$850

HK$966 total

includes taxes & fees

8 Oct - 9 Oct

A room with two blue armchairs, a green armchair, and a woven ottoman. A large landscape painting is on the wall.

A hotel entrance with a glass door, stone facade, and a covered walkway.

A La Quinta Inn with a red and white exterior, a covered entrance, and a parking lot with several cars.

15. La Quinta Inn by Wyndham Buffalo Airport

Buffalo

Matt

HK$595

HK$677 total

includes taxes & fees

28 Sept - 29 Sept

A modern kitchen with a central island, wooden cabinets, and a bar area with stools.

A hotel room with a bed, a TV, a desk, a lamp, and a mirror.

A modern hotel lobby with a curved seating area, a flat-screen TV, and a dining area.

A modern hotel with a flat roof, large windows, and a covered entrance.

16. Springhill Suites Buffalo Airport

Buffalo

Matthias

HK$1,087

HK$1,237 total

includes taxes & fees

12 Oct - 13 Oct

An outdoor seating area with orange chairs and tables, a covered area with umbrellas, and a building entrance with glass doors and interior lighting.

A modern hotel with a prominent 'Aloft' sign, large windows, and a well-lit entrance.

A modern cafe with a wooden counter, clear menu boards, and a variety of food and drink dispensers.

17. Aloft by Marriott Buffalo Airport

Buffalo

Gene

HK$935

HK$1,064 total

includes taxes & fees

18 Oct - 19 Oct

A parking lot with cars and a covered walkway.

An indoor swimming pool with clear glass ceilings, tiled floors, and multiple windows offering views of the outdoors.

A hotel room with a bed, a desk, a sofa, and a painting on the wall.

18. Hyatt Place Buffalo/Amherst

Buffalo

Samuel

HK$1,263

HK$1,437 total

includes taxes & fees

11 Oct - 12 Oct

A Holiday Inn Express building with a covered entrance, a flag, and a sign indicating the address.

A hotel room with a large bed, a desk with a flat-screen TV, a sofa, a lamp, and a window with curtains.

A modern hotel lobby with a circular glass table surrounded by chairs, a bar area, and seating with orange cushions.

A hotel lobby with a reception desk, seating area, and a long corridor.

19. Holiday Inn Express Cheektowaga North East by IHG

Buffalo

Nadia

HK$1,091

HK$1,273 total

includes taxes & fees

21 Oct - 22 Oct

A Hampton Inn hotel with a modern facade, large windows, and a well-maintained parking lot.

An outdoor patio with a table and chairs, a blue sofa, and a large umbrella.

A kitchen area with a chalkboard wall displaying cooking instructions and a sign promoting waffles.

A vending machine with snacks and drinks, including Coca-Cola, Sprite, and various chips.

20. Hampton Inn Buffalo-Airport / Galleria Mall

Buffalo

Maylin

HK$1,132

HK$1,322 total

includes taxes & fees

14 Oct - 15 Oct

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Top Depew Hotel Reviews

Hampton Inn Buffalo - Amherst, NY

10/10 Excellent

"Easy, pleasant, and seemless stay overall"

Comfort Inn & Suites Niagara Falls Blvd USA

8/10 Good

"Well located for visiting the Niagara Falls area"

Holiday Inn Express Grand Island - Niagara Falls by IHG

10/10 Excellent

"Clean room and everyone here was extremely nice and helpful!"

Best Western Buffalo Inn & Suites

10/10 Excellent

"Clean room , and the rain shower was a nice touch"

La Quinta Inn & Suites by Wyndham Buffalo Amherst

10/10 Excellent

"A good place to stay near Niagara."

Fairbridge Inn Express Buffalo Airport Williamsville

10/10 Excellent

"I want To give a Big Thank You to Amanda. We as tourists that we are not from the area need information and Amanda was the best at the hotel , so sweet, patient and willing to help Customers answering questions and giving suggestions. She is wonderful Thanks to her i was Not lost and i got to go to Niagara falls very easy and very affordable price. Thank you Amanda !"

M Hotel Buffalo

8/10 Good

"Rooms were fine but a little outdated. Looked like the hotel is under going renovations to address this."

Studio 6 Corporate Extended Stay Buffalo Amherst NY

10/10 Excellent

"🌎"

More cheap stays in Depew

Fairbridge Inn Express Buffalo Airport Williamsville

7200 Transit Road Buffalo NY

HK$431

HK$490 total

23 Sept - 24 Sept

includes taxes & fees

4.8/10 (1,137 reviews)

Sleep Inn & Suites Buffalo Airport

100 Holtz Dr Buffalo NY

HK$551

HK$626 total

20 Oct - 21 Oct

includes taxes & fees

Best Western Summit Inn

9500 Niagara Falls Blvd Niagara Falls NY

HK$706

HK$805 total

5 Oct - 6 Oct

includes taxes & fees

Comfort Inn University

1 Flint Rd Buffalo NY

HK$732

HK$832 total

18 Oct - 19 Oct

includes taxes & fees

Motel 6 Amherst, NY - Buffalo

4400 Maple Rd Buffalo NY

HK$745

HK$848 total

23 Sept - 24 Sept

includes taxes & fees

6.6/10 (1,002 reviews)

Holiday Inn Express Grand Island - Niagara Falls by IHG

2761 Long Road Grand Island NY

HK$827

HK$941 total

27 Sept - 28 Sept

includes taxes & fees

8.8/10 Excellent! (2,132 reviews)

Hotels in Depew with star-rating

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Buffalo Airport Hotel and Holiday Inn Express Grand Island - Niagara Falls by IHG. See all available top hotels, or vacation rentals in Depew.

What are some of the best holiday rentals that Depew has to offer?

HTR Niagara: This holiday home rental outside of Depew is on the riverwalk, and equipped with air conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities such as a coffee maker and free parking are also available for your convenience. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

What are some accommodation options with pools in Depew?

M Hotel Buffalo: Hotel, 4-minute walk from Walden Galleria Mall. Features buffet, an indoor pool and free self parking. Holiday Inn Express Grand Island - Niagara Falls by IHG and Hyatt Regency Buffalo / Hotel and Conference Center are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. A top sight in the area is Highmark Stadium. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.

What should I see while I'm in Depew?

Highmark Stadium is a notable place to visit in the area. You'll also find Walden Galleria Mall and Samuel's Grande Manor in the area. Take a look at what more there is to see and do in Expedia's Depew guide.

How can I get around Depew?

If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the seasonal weather like in Depew?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

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Depew hotels from HK$490

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Depew

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Depew hotels

1. Fairfield Inn & Suites by Marriott Buffalo Airport

2. Comfort Inn & Suites Buffalo Airport

3. Courtyard Buffalo Airport

4. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

5. Tru by Hilton Williamsville Buffalo Airport

6. Sleep Inn & Suites Buffalo Airport

7. Buffalo Airport Hotel

8. Homewood Suites by Hilton Buffalo Airport

9. Hilton Garden Inn Buffalo Airport

10. Hampton Inn & Suites Buffalo Airport

11. TownePlace Suites Buffalo Airport

12. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

13. Salvatores Grand Hotel

14. The Delavan Hotel & Spa

15. La Quinta Inn by Wyndham Buffalo Airport

16. Springhill Suites Buffalo Airport

17. Aloft by Marriott Buffalo Airport

18. Hyatt Place Buffalo/Amherst

19. Holiday Inn Express Cheektowaga North East by IHG

20. Hampton Inn Buffalo-Airport / Galleria Mall

Top Depew Hotel Reviews

Hampton Inn Buffalo - Amherst, NY

Comfort Inn & Suites Niagara Falls Blvd USA

Holiday Inn Express Grand Island - Niagara Falls by IHG

Best Western Buffalo Inn & Suites

La Quinta Inn & Suites by Wyndham Buffalo Amherst

Fairbridge Inn Express Buffalo Airport Williamsville

M Hotel Buffalo

Studio 6 Corporate Extended Stay Buffalo Amherst NY

More cheap stays in Depew

Fairbridge Inn Express Buffalo Airport Williamsville

Sleep Inn & Suites Buffalo Airport

Best Western Summit Inn

Comfort Inn University

Motel 6 Amherst, NY - Buffalo

Holiday Inn Express Grand Island - Niagara Falls by IHG

Hotels in Depew with star-rating

Frequently asked questions

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