
South Carolina Midlands hotels from HK$469
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in South Carolina Midlands
Apart hotel
Check prices for these dates
Our top choices for South Carolina Midlands hotels

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is HK$1,120
HK$1,243 total
includes taxes & fees
26 Apr - 27 Apr

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
8.6 out of 10, Excellent, (1,000 reviews)
The price is HK$1,026
HK$1,149 total
includes taxes & fees
12 Apr - 13 Apr

Lexington Expo Hotel by IHG
Lexington Expo Hotel by IHGLexington
9.2 out of 10, Wonderful, (1,006 reviews)
The price is HK$963
HK$1,069 total
includes taxes & fees
12 Apr - 13 Apr

Hampton Inn & Suites Lexington Columbia
Hampton Inn & Suites Lexington ColumbiaLexington
9.8 out of 10, Exceptional, (628 reviews)
The price is HK$1,021
HK$1,134 total
includes taxes & fees
15 Apr - 16 Apr

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,005 reviews)
The price is HK$1,063
HK$1,180 total
includes taxes & fees
20 Apr - 21 Apr

Best Western Plus Lexington Inn
Best Western Plus Lexington InnDowntown Lexington
9.2 out of 10, Wonderful, (1,002 reviews)
The price is HK$881
HK$978 total
includes taxes & fees
26 Apr - 27 Apr

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (772 reviews)
The price is HK$940
HK$1,043 total
includes taxes & fees
13 Apr - 14 Apr

Tru By Hilton Fort Mill, SC
Tru By Hilton Fort Mill, SCFort Mill
9.0 out of 10, Wonderful, (599 reviews)
The price is HK$700
HK$777 total
includes taxes & fees
12 Apr - 13 Apr

Hyatt Place Florence Downtown
Hyatt Place Florence DowntownFlorence
9.0 out of 10, Wonderful, (1,004 reviews)
The price is HK$956
HK$1,070 total
includes taxes & fees
12 Apr - 13 Apr

Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHGLatta
9.6 out of 10, Exceptional, (568 reviews)
The price is HK$924
HK$1,007 total
includes taxes & fees
6 Apr - 7 Apr

Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20Florence
9.2 out of 10, Wonderful, (606 reviews)
The price is HK$892
HK$999 total
includes taxes & fees
6 Apr - 7 Apr

Hampton Inn & Suites Columbia Killian Road
Hampton Inn & Suites Columbia Killian RoadColumbia
9.2 out of 10, Wonderful, (1,022 reviews)
The price is HK$1,218
HK$1,364 total
includes taxes & fees
5 Apr - 6 Apr

Hampton Inn Rock Hill
Hampton Inn Rock HillRock Hill
9.2 out of 10, Wonderful, (1,002 reviews)
The price is HK$704
HK$781 total
includes taxes & fees
6 Apr - 7 Apr

Springhill Suites by Marriott Columbia near Fort Jackson
Springhill Suites by Marriott Columbia near Fort JacksonColumbia
9.4 out of 10, Exceptional, (648 reviews)
The price is HK$889
HK$996 total
includes taxes & fees
12 Apr - 13 Apr

SpringHill Suites by Marriott Charlotte at Carowinds
SpringHill Suites by Marriott Charlotte at CarowindsCharlotte
9.2 out of 10, Wonderful, (873 reviews)
The price is HK$826
HK$951 total
includes taxes & fees
19 Apr - 20 Apr

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,001 reviews)
The price is HK$932
HK$1,035 total
includes taxes & fees
20 Apr - 21 Apr

SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott OrangeburgOrangeburg
8.8 out of 10, Excellent, (722 reviews)
The price is HK$1,010
HK$1,122 total
includes taxes & fees
2 Apr - 3 Apr

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
The price is HK$893
HK$991 total
includes taxes & fees
13 Apr - 14 Apr

La Quinta Inn & Suites by Wyndham Rock Hill
La Quinta Inn & Suites by Wyndham Rock HillRock Hill
9.0 out of 10, Wonderful, (1,103 reviews)
The price is HK$659
HK$732 total
includes taxes & fees
5 Apr - 6 Apr

Country Inn & Suites by Radisson, Columbia Airport, SC
Country Inn & Suites by Radisson, Columbia Airport, SCCayce
8.4 out of 10, Very good, (1,006 reviews)
The price is HK$859
HK$953 total
includes taxes & fees
19 Apr - 20 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in South Carolina Midlands
Cabin

8.6 out of 10, Excellent, (249 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeastern United States attractions
Learn more about South Carolina Midlands
With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

Top South Carolina Midlands Hotel Reviews

Comfort Inn & Suites Florence Center Area
8/10 Good
More cheap stays in South Carolina Midlands

Motel 6 Fort Mill, SC - Charlotte
3541 Foothills Way Fort Mill SC
The price is HK$409 per night from 30 Mar to 31 Mar
HK$409
HK$469 total
30 Mar - 31 Mar
includes taxes & fees
6.6/10 (1,010 reviews)
Hotels in South Carolina Midlands with star-rating

4 Star Hotels
13 properties
Explore a world of travel with Expedia
- Apartments in South Carolina
- Castles in South Carolina
- Cheap Hotels in Lugoff
- Condo Rentals in Lugoff
- Pet-Friendly Hotel Hotels in Blythewood
- 5 Star Hotels in West Columbia
- Cheap Hotels in Columbia
- 5 Star Hotels in Columbia
- Downtown Columbia Hotels
- B&B in South Carolina
- Lgbt Welcoming Hotel Hotels in Killian
- Family Hotel Hotels in West Columbia
- Luxury Hotel Hotels in Columbia
- Hotels near Township Auditorium
- Apartments in Lugoff
- Lgbt Welcoming Hotel Hotels in Rosewood
- Lodges in South Carolina
- Hotels near Columbiana Centre
- Wyndham Hotels in Cayce
- 3 Star Hotels in Columbia
- Rv Parks in South Carolina Midlands
- Spa Hotel Hotels in West Columbia
- B&B in Blythewood
- Luxury Hotel Hotels in South Carolina
- Cabin Rentals in South Carolina
- Motel 6 Hotels in Elgin
- Dalzell Hotels
- Farmstay in South Carolina
- Hotels near Wilson House
- Business Hotel Hotels in West Columbia
- Cheap Hotels in Downtown Columbia
- 5 Star Hotels in Waverly
- Motel 6 Hotels in Ridgeway
- Luxury Hotel Hotels in Lugoff
- Hotels near Oak Hills Golf Club
- Motels in Columbia
- Lgbt Welcoming Hotel Hotels in Arsenal Hill
- 4 Star Hotels in Columbia
- Hotels near Congaree National Park
- Hotels near Village at Sandhill Mall
- Hotels near Columbia Station
- Hotels near EdVenture Children's Museum
- Guest Houses in South Carolina
- Villas in South Carolina
- Casino Hotel Hotels in Columbia
- Hotels near Plex Indoor Sports
- Hotels near Williams Brice Stadium
- Romantic Hotel Hotels in Columbia
- Rv Parks in South Carolina
- 4 Star Hotels in Blythewood
- Lugoff Hotels
- Best Western Hotels in South Carolina Midlands
- Rosewood Hotels
- Resorts in South Carolina
- 5 Star Hotels in Blythewood
- Hotels near Shaw Air Force Base
- Irmo Hotels
- Hotels near University of South Carolina
- Hotels near Irmo Community Park
- Motel 6 Hotels in Columbia
- Vacation Homes in Blythewood
- Hotels near Columbia Museum of Art
- Vacation Homes in South Carolina
- Cassatt Hotels
- Spa Hotel Hotels in Columbia
- 3 Star Hotels in Downtown Columbia
- Camden Hotels
- Hilton Hotels in University Hill
- Hotels near South Carolina State Fairgrounds
- Hotels near Columbia Place Mall
- Hotels near Bethesda Presbyterian Church
- Wedding Hotels in Columbia
- La Quinta Inn & Suites Hotels in Blythewood
- Hotels near Columbia Metropolitan
- Casino Hotel Hotels in South Carolina
- Blythewood Hotels
- Hotels near Allen University
- South Carolina Hotels
- Cheap Hotels in University Hill
- Hotels near Historic Winnsboro Town Clock
- Cheap Hotels in South Carolina
- Elgin Hotels








































































































































