San Antonio South Texas Medical Center Hotels: 2026 Limited-Time Hotel Deals @Expedia

A modern medical building with reflective glass windows and a clear sky.

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Our top choices for South Texas Medical Center hotels

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

An indoor swimming pool with multiple lanes, safety signs, and a view of the outside through large windows.

A hotel room with two beds, a TV, a desk with a lamp, and a dresser.

A spacious indoor area with a long wooden reception desk, multiple seating arrangements, and large windows providing natural light.

1. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 2.9 km from South Texas Medical Center

Alba

HK$706

HK$835 total

includes taxes & fees

19 Oct - 20 Oct

A modern living room with a fireplace, a flat-screen TV, and a stone accent wall.

A Fairfield by Marriott Inn & Suites building with a modern design, featuring a prominent entrance with a covered walkway and a parking lot in front.

A modern cafe with wooden furniture, white tables, and a brick wall.

A swimming pool with a wooden ceiling, lounge chairs, and a view of trees and a building.

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

Medical Center District, 1 km from South Texas Medical Center

Freddie

HK$751

HK$876 total

includes taxes & fees

7 Oct - 8 Oct

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

A hotel room with a large bed, a desk, and a chair.

A courtyard with outdoor seating, a fire pit, and a covered area.

A hotel entrance with a covered walkway, a wet driveway, and a tree in the foreground.

3. Courtyard by Marriott Medical Center San Antonio

Medical Center District, 1.3 km from South Texas Medical Center

Erik

HK$770

HK$910 total

includes taxes & fees

7 Oct - 8 Oct

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

A hotel lobby with a reception desk, seating area, and a chandelier.

A gym with multiple cardio machines, including treadmills and elliptical trainers, arranged in a spacious room with a carpeted floor and neutral-colored walls.

A hotel with a red-roofed entrance, multiple floors, and a visible flag.

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 2.4 km from South Texas Medical Center

Maria

HK$697

HK$823 total

includes taxes & fees

7 Oct - 8 Oct

A hotel pool area with lounge chairs and a building with large windows in the background.

A large banquet hall with round tables, chairs, and chandeliers.

A hotel lobby with a seating area, a large potted plant, a decorative wall, and a vintage car display.

A large conference room with a high ceiling, large windows, and a patterned carpet.

5. The Westin San Antonio North

3.2 km from South Texas Medical Center

Jack

HK$733

HK$879 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with two beds, a desk, a chair, a mirror, and a bathroom.

A clean, modern reception area with a large number '6' sign, a poster advertising a direct book service, and a view of the outside through a window.

A laundry facility with multiple washing machines, a drying rack, and instructional posters on the wall.

A stone facade with a 'welcome' sign, a blue door, and a parking sign.

6. Studio 6 San Antonio, Tx - Northwest Medical Center

Medical Center District, 2.7 km from South Texas Medical Center

Ruben

HK$368

HK$430 total

includes taxes & fees

7 Oct - 8 Oct

A modern kitchen with a large window, wooden counter, and two bar stools.

A reception desk with a modern design, featuring a white counter and dark cabinets. There are three pendant lights above the desk, and a large window with a view of greenery outside.

A compact kitchenette with a built-in microwave, a black refrigerator, and a wooden countertop.

A Park Inn hotel with a brick facade, multiple parking spaces, and a clear sky.

7. Park Inn by Radisson, Medical Center

Medical Center District, 1 km from South Texas Medical Center

Joanne

HK$527

HK$615 total

includes taxes & fees

19 Oct - 20 Oct

A building entrance with a glass door, a Pepsi vending machine, and a yellow bollard.

A hotel with a prominent 'OYO INN & SUITES' sign, featuring a two-story structure with balconies and a covered entrance.

A hotel reception area with a glass door entrance, a reception desk, and a wall-mounted sign for the OYO hotel.

A hotel room with two beds, a television, a desk with a computer, and a door.

8. OYO Inn & Suites Medical Center San Antonio

Medical Center District, 3.1 km from South Texas Medical Center

Melanie

HK$504

HK$639 total

includes taxes & fees

2 Oct - 3 Oct

A gas station with a sign for 'Atria Inn & Suites' and a 'Clearance - 12' sign.

A hotel room with a bed, two bedside tables with lamps, a desk with a telephone, a mirror, and a door leading to another room.

A hotel entrance with an Atria Inn & Suites sign, a Classic Collins store, and a clear sky.

A hotel room with a sofa, a desk, a chair, a bed, and a mirror.

9. Atria Inn & Suites

Medical Center District, 2.2 km from South Texas Medical Center

José

HK$453

HK$529 total

includes taxes & fees

8 Oct - 9 Oct

A reception area with a glass door entrance, a reception desk, and a wall-mounted fire extinguisher.

A spacious lobby with a large refrigerator, a vending machine, and a seating area.

A small, modern room with two brown leather sofas, a black cabinet, and a window with blinds.

A small, modern room with a wooden dining table, a mirror, a TV, and a small kitchenette.

10. Motel 6 San Antonio, TX - Fiesta Trails

2.9 km from South Texas Medical Center

Alexis

HK$353

HK$412 total

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a large bed, a desk with a chair, a television on a stand, and a mirror on the wall.

A bathroom with a granite countertop sink, a mirror, a shower with a glass door, and a toilet.

A building with a red roof and a sign reading "Flex Studios."

A building with a yellow facade and a sign reading "Flex Studios."

11. Flex Studios

Medical Center District, 2.7 km from South Texas Medical Center

Jasper

HK$345

HK$408 total

includes taxes & fees

8 Oct - 9 Oct

A modern bedroom with a large bed, bedside tables, a desk, and a chair.

A swimming pool with a stone wall and a 'No Diving' sign, surrounded by a fence and a building with a stone facade.

A hotel reception area with a large number '6' sign, a poster advertising direct booking, and a view of the outside through a window.

A building with a stone facade, a prominent '6' sign, and a parking lot with marked handicapped spaces.

12. Motel 6 San Antonio, TX - Northwest Medical Center

Medical Center District, 2.8 km from South Texas Medical Center

Rachel

HK$353

HK$449 total

includes taxes & fees

16 Oct - 17 Oct

An indoor swimming pool with a hot tub, tiled flooring, and a seating area with tables and chairs.

A hotel lobby with a curved reception desk, a seating area with a sofa and chairs, and a hallway leading to other rooms.

An outdoor patio area with multiple tables and chairs, covered by a pergola structure.

A multi-story hotel with a central atrium, a parking lot, and surrounding greenery.

13. Drury Inn & Suites Near La Cantera Parkway

La Cantera District, 9 km from South Texas Medical Center

Eduardo

HK$737

HK$872 total

includes taxes & fees

8 Oct - 9 Oct

A covered outdoor seating area with lounge chairs and umbrellas, a pool in the background, and potted plants.

A spacious living area with a large sectional sofa, multiple coffee tables, and a wooden partition.

A modern office space with two desks, chairs, and a large window.

A bar area with a granite countertop, multiple bar stools, and hanging pendant lights.

14. Embassy Suites by Hilton San Antonio Landmark

La Cantera District, 8.7 km from South Texas Medical Center

Lenita

HK$1,417

HK$1,675 total

includes taxes & fees

25 Oct - 26 Oct

A Holiday Inn Express reception desk with a modern design, featuring a large illuminated sign, a reception area, and a potted plant.

A poolside area with lounge chairs and a metal railing.

A Holiday Inn Express building with a modern design, large windows, and a covered entrance area.

A hotel room with a brick wall, a wooden headboard, two beds with white bedding, a bedside table with a lamp, and a wall-mounted light fixture.

15. Holiday Inn Express San Antonio-Airport by IHG

9.2 km from South Texas Medical Center

Liz

HK$824

HK$974 total

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

A reception desk with a computer, framed pictures on the wall, and pendant lighting.

An outdoor patio with a pergola, pool, and outdoor seating area.

A hotel entrance with a covered walkway, brick facade, and a sign indicating it is a Heritage Inn & Suites.

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central, 9.5 km from South Texas Medical Center

Amy

HK$627

HK$742 total

includes taxes & fees

7 Oct - 8 Oct

An outdoor patio with a stone fireplace, wicker furniture, and a view of apartment buildings.

A spacious living area with a sofa set, multiple chairs, a coffee table, and a chandelier.

A modern hotel lobby with a fireplace, comfortable seating, and a flat-screen TV.

A modern bar area with a wooden ceiling, bar stools, and a television.

17. Doubletree By Hilton San Antonio Northwest

La Cantera District, 9.7 km from South Texas Medical Center

Vicente

HK$1,147

HK$1,147 total

includes taxes & fees

26 Oct - 27 Oct

A modern hotel with a prominent sign reading "LA QUINTA".

A reception area with wooden reception desks, a cityscape mural, and a modern chandelier.

A modern bar area with wooden stools and a marble table, surrounded by seating with patterned cushions.

A modern lounge area with wooden and colorful seating, a round table, and a flat-screen TV on the wall.

18. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

9.1 km from South Texas Medical Center

john

HK$819

HK$956 total

includes taxes & fees

18 Oct - 19 Oct

A multi-level hotel atrium with a central courtyard, outdoor seating, and a pool.

A spacious bar area with a long counter, multiple stools, and a television screen.

A building with a large arched doorway, a balcony with a railing, and a tree with green foliage in the foreground.

19. Estancia del Norte San Antonio, Tapestry Collection by Hilton

8.7 km from South Texas Medical Center

Adamaris

HK$958

HK$1,133 total

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with seating and a staircase leading to an upper level.

A spacious indoor dining area with multiple tables and chairs, a high ceiling with recessed lighting, and a view of the restaurant kitchen through a glass partition.

A modern building with "EMBASSY SUITES" signage, featuring a prominent entrance and landscaped surroundings.

An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.

20. Embassy Suites by Hilton San Antonio Airport

Uptown Central, 9.6 km from South Texas Medical Center

Arianna

HK$965

HK$1,141 total

includes taxes & fees

11 Oct - 12 Oct

View all properties

Compare popular hotels close to South Texas Medical Center

Property	Property class	Guest rating
Drury Inn & Suites San Antonio Northwest Medical Center	9.2 Wonderful 1,477 reviews	View
Fairfield Inn & Suites by Marriott San Antonio Medical Center	9.0 Wonderful 1,090 reviews	View
Courtyard by Marriott Medical Center San Antonio	8.8 Excellent 1,005 reviews	View
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW	8.4 Very good 3,700 reviews	View
The Westin San Antonio North	8.4 Very good 1,643 reviews	View

Top South Texas Medical Center Hotel Reviews

Studio 6 San Antonio, Tx - Northwest Medical Center

10/10 Excellent

"Everything was great for the price for 1 bed room"

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

10/10 Excellent

"Excellent loved it and will book again"

Hyatt Place San Antonio-Northwest/Medical Center

10/10 Excellent

"all great , perfect"

San Antonio Marriott Northwest Medical Center

10/10 Excellent

"The property was beautiful the staff was incredible"

Park Inn by Radisson, Medical Center

10/10 Excellent

"Rooms were clean"

Atria Inn & Suites

10/10 Excellent

"Had a great stay. Will come back soon."

Cozy 2B condo with WiFi, AC in Medical Center, San Antonio

10/10 Excellent

"Very comfortable place, apartment has all necessary utensils on the kitchen, bedrooms and bathrooms, food and coffee close by, good price for everything has to offer. Thanks again for letting us stay at your property."

Motel 6 San Antonio, TX - Northwest Medical Center

10/10 Excellent

"The customer service rep at check in and housekeeping, we’re very helpful and very courteous."

Flex Studios

10/10 Excellent

"Its not to bad a place. Very affordable and reasonable. I Have stayed at way worse. I plan on staying about two months. I been there two weeks."

Frequently asked questions

What's the area like around South Texas Medical Center?

South Texas Medical Center is located in a walkable area of San Antonio known for its stunning river views and cycling. If you're looking for a convenient place to stay, take a look at the 35 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to South Texas Medical Center?

Fairfield Inn & Suites by Marriott San Antonio Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.6 mi (1 km) from South Texas Medical Center. Other good options close by include Courtyard by Marriott Medical Center San Antonio and Park Inn by Radisson, Medical Center.

How many hotels should I expect to find close to South Texas Medical Center?

Expedia has 35 hotels and other accommodation options within a mile from South Texas Medical Center.

If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?

Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near South Texas Medical Center.

What can I see and do near South Texas Medical Center?

You can watch performances at Woodlawn Theater, Sheldon Vexler Theatre and Laugh Out Loud Comedy Club if you're interested in local theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Wonderland of the Americas Mall, Huebner Oaks and Ingram Park Mall might be just the ticket while you're in the area around South Texas Medical Center.

San Antonio South Texas Medical Center Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Star rating

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Our top choices for South Texas Medical Center hotels

1. Drury Inn & Suites San Antonio Northwest Medical Center

2. Fairfield Inn & Suites by Marriott San Antonio Medical Center

3. Courtyard by Marriott Medical Center San Antonio

4. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

5. The Westin San Antonio North

6. Studio 6 San Antonio, Tx - Northwest Medical Center

7. Park Inn by Radisson, Medical Center

8. OYO Inn & Suites Medical Center San Antonio

9. Atria Inn & Suites

10. Motel 6 San Antonio, TX - Fiesta Trails

11. Flex Studios

12. Motel 6 San Antonio, TX - Northwest Medical Center

13. Drury Inn & Suites Near La Cantera Parkway

14. Embassy Suites by Hilton San Antonio Landmark

15. Holiday Inn Express San Antonio-Airport by IHG

16. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

17. Doubletree By Hilton San Antonio Northwest

18. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

19. Estancia del Norte San Antonio, Tapestry Collection by Hilton

20. Embassy Suites by Hilton San Antonio Airport

Compare popular hotels close to South Texas Medical Center

Top South Texas Medical Center Hotel Reviews

Studio 6 San Antonio, Tx - Northwest Medical Center

Holiday Inn Express & Suites San Antonio Medical-Six Flags by IHG

Hyatt Place San Antonio-Northwest/Medical Center

San Antonio Marriott Northwest Medical Center

Park Inn by Radisson, Medical Center

Atria Inn & Suites

Cozy 2B condo with WiFi, AC in Medical Center, San Antonio

Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Frequently asked questions