Best Upstate South Carolina Hotels in 2026 from HK$489 - Fully Refundable Options

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

An outdoor seating area with sofas, a fire pit, and string lights.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

1. Tru by Hilton Spartanburg

Spartanburg

Jeremy

HK$829

HK$921 total

includes taxes & fees

13 Sept - 14 Sept

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

2. Four Points by Sheraton Spartanburg

Spartanburg

Travis

HK$840

HK$932 total

includes taxes & fees

13 Sept - 14 Sept

A modern interior with a fireplace, seating, and a wooden wall.

A hotel room with a flat-screen TV, a desk with a chair, a bed, and framed pictures on the wall.

A modern interior with seating areas, tables, a flat-screen TV, and a fireplace.

A reception desk with a 'Welcome to Hampton' sign and a cityscape photograph.

3. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

Kathy

HK$862

HK$956 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

4. Comfort Suites At WestGate Mall

Spartanburg

Brittney

HK$715

HK$794 total

includes taxes & fees

27 Sept - 28 Sept

A modern lobby with a reception desk, seating area, and a television screen.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

5. Best Western Spartanburg I-26

Spartanburg

Jonathan

HK$700

HK$777 total

includes taxes & fees

10 Sept - 11 Sept

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A spacious lobby with a bar area, seating, and large windows.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

6. Hilton Garden Inn Spartanburg

Spartanburg

Stan

HK$926

HK$1,028 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A vending machine area with snacks and beverages, and a display of green apples.

7. Home2 Suites by Hilton Duncan

Duncan

Lilia

HK$894

HK$992 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.

A large indoor swimming pool with a diving board, multiple doors, and seating areas.

8. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

Michael

HK$804

HK$893 total

includes taxes & fees

13 Sept - 14 Sept

A spacious living area with a modern design, featuring a sofa, chairs, a fireplace, and a television.

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern dining area with round tables and chairs, a stone wall, and a large window with patterned curtains.

A Comfort Suites hotel with a modern design, featuring a central entrance, multiple parking spaces, and a landscaped area with small trees.

9. Comfort Suites Greenville Airport

Greenville

Chandler

HK$773

HK$875 total

includes taxes & fees

27 Sept - 28 Sept

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

A multi-level atrium with a modern design, featuring a central open space with tiered seating and tables, surrounded by balconies with greenery.

An indoor swimming pool with lounge chairs and potted plants.

10. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Pedro

HK$804

HK$911 total

includes taxes & fees

20 Sept - 21 Sept

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A pool area with lounge chairs and a sign for Best Western Plus.

11. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Sara

HK$649

HK$714 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A modern bar area with a wooden counter, a digital menu board, and a variety of liquor bottles.

A modern hotel lobby with a bar area, seating, and a large window providing natural light.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

12. Courtyard by Marriott Greenville Mauldin

Greenville

LEEKYA

HK$933

HK$1,026 total

includes taxes & fees

6 Sept - 7 Sept

A modern kitchen with a central island, bar stools, and pendant lighting.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

13. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

michelle

HK$862

HK$956 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and a brick pillar.

A hotel lobby with a reception desk, a patterned carpet, and a large abstract wall art piece.

14. Hampton Inn & Suites Greenville Airport, SC

Greenville

Kristina

HK$821

HK$930 total

includes taxes & fees

13 Sept - 14 Sept

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

15. Spartanburg Marriott

Spartanburg

Sarah

HK$925

HK$1,027 total

includes taxes & fees

13 Sept - 14 Sept

A modern lounge area with a blue sofa, a round coffee table, a patterned ottoman, and a wooden reception desk.

A hotel room with two beds, a desk, a TV, and a patterned carpet.

A modern lobby with a blue sofa, a round coffee table, and a brown armchair.

A gym with treadmills, stationary bikes, and exercise balls.

16. Fairfield Inn & Suites by Marriott Greenville Simpsonville

Simpsonville

Carole

HK$626

HK$689 total

includes taxes & fees

20 Sept - 21 Sept

A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.

A gym with treadmills, dumbbells, and a wall with motivational words.

A hotel room with two beds, a nightstand, and a wall-mounted TV.

A Best Western Plus hotel with a parking lot and multiple cars parked in front.

17. Best Western Plus Spartanburg

Spartanburg

Jamie

HK$715

HK$810 total

includes taxes & fees

6 Sept - 7 Sept

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A Holiday Inn Express & Suites hotel with a covered entrance and multiple floors.

18. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Elizabeth

HK$862

HK$957 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a blue sofa, a grey armchair, and a patterned rug.

A modern kitchen with a microwave, refrigerator, and juice dispenser.

A hotel room with a desk, chair, flat-screen TV, microwave, and a large window with curtains.

A modern dining area with multiple tables and chairs, a counter with a refrigerator, and large windows providing natural light.

19. Comfort Inn & Suites Greer - Greenville

Greer

Tonya

HK$804

HK$903 total

includes taxes & fees

27 Sept - 28 Sept

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A hotel room with two beds, a desk, a TV, and a window with curtains.

20. Best Western Spartanburg Northwest

Spartanburg

Porsche

HK$726

HK$822 total

includes taxes & fees

6 Sept - 7 Sept

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Holiday Rentals in Upstate South Carolina

Aparthotel

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

stayAPT Suites Greenville-Haywood Mall

Greenville

"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."

Cabin

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A swimming pool with lounge chairs and a covered area with tables and chairs.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

A two-story house with a front porch, a small garden, and a wooden fence.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Decent room. Very large suite for the price. Beds are too low."

Aparthotel

A modern living room with a flat-screen TV, a dining area with a round table and chairs, a kitchen with dark cabinets and a refrigerator, and a sofa with a patterned pillow.

A pool area with a covered seating area, lounge chairs, and umbrellas.

A spacious living area with a ceiling fan, a flat-screen TV, and comfortable seating.

A modern kitchen with a coffee bar, wooden wall, and three orange bar stools.

Landing Apartments - Lyman

Lyman

"Great room that was nice and clean. Smooth check-in."

Cabin

A wooden interior with a table, chair, and a hanging lantern.

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A rustic cabin with a porch, wooden steps, and a picnic table.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A modern kitchen with blue cabinets, a central island, and a spiral staircase leading to an upper level.

A modern kitchen with blue cabinets, stainless steel appliances, and a large island.

A two-story building with a covered porch, a flagpole, and a landscaped front yard.

A modern living room with a fireplace, a large TV, and a kitchen area with blue cabinets and a bar.

Greenwood Getaway w/ Furnished Patio & Lake View

Greenwood

"Wonderful stay and would definitely stay again! Reasonable price for the luxury place with everything that you could ask for in a rental. Close to restaurants and bars if that is your thing and right near the lake with beautiful views!! We loved our stay!"

Cottage

A cozy bedroom with a bed, a nightstand, a lamp, a small table, a window, and a Christmas tree.

A kitchen with wooden cabinets, a microwave, a stove, and a refrigerator.

A living room with a sofa, ottoman, and a leather chair with a 'Family' pillow. There is a ceiling fan, a plant, and a window with curtains.

A home interior with a metal shelf unit displaying various items, a hallway with wooden flooring, and a door leading to another room.

8 Mi to Clemson: Peaceful Family Home w/ Yard

Seneca

"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."

Apartment

A modern kitchen with a central island, stainless steel appliances, and pendant lighting.

A modern kitchen with white cabinets, stainless steel appliances, and a central island with bar stools.

A covered patio area with outdoor seating, large windows, and a white exterior.

A two-story house with a front porch, a garage, and a small front yard with landscaping.

Steps to Lake Greenwood: Waterfront Gem w/ Patio

Greenwood

"Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon."

Cottage

A covered patio with outdoor seating, a view of a parking lot and distant landscape.

A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.

A single-story house with a covered porch, a small garden, and a sign indicating it is a rental property.

A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table.

Stunning Lakefront Retreat w/ Dock Access!

Greenwood

Cottage

A covered porch with wooden railings and a table with chairs.

A cabin with a wooden deck, a gravel driveway, and a forested backdrop.

A two-story building with a covered porch, stone foundation, and a gravel driveway.

A kitchen with a dining area, a sliding glass door to a deck, and a ceiling fan.

9 Mi to Devils Fork State Park: Getaway w/ Porch!

Tamassee

"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"

Cottage

A balcony with wicker chairs, a white railing, and a view of a forest.

A spacious kitchen with white cabinets, granite countertops, and a large island.

A spacious room with a large window, a wooden chair, and a view of trees.

A wooden deck with a concrete path leading to a dock, surrounded by tall trees and a body of water.

Waterfront Lake Hartwell Vacation Rental w/ Dock!

Townville

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Martin Farm and Heritage Park.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

8/10 Good

"Enjoyed the stay, it was clean and would stay again"

Hilton Greenville

10/10 Excellent

"Beautiful hotel"

Spartanburg Marriott

10/10 Excellent

"From the first moment, we were impressed with the property. The common areas are clean. The registration representative was friendly and personable. All questions were answered. The room was clean with a great view. the location was perfect for our event. We went to see "Backbone" at the Chapman Cultural Arts center less than a mile away. The streets were quiet and we felt safe walking to and from the event after 9pm. Very happy with choice and will visit again."

Comfort Suites At WestGate Mall

8/10 Good

"None"

Grand Bohemian Lodge Greenville, Autograph Collection

8/10 Good

"Nice property that is extremely well located relative to downtown Greenville. Staff and facilities were first rate but I found the decor slightly tacky."

More cheap stays in Upstate South Carolina

Days Inn by Wyndham Greenville

60 Roper Mountain Rd Greenville SC

HK$473

HK$521 total

7 Sept - 8 Sept

includes taxes & fees

5.6/10 (1,000 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

HK$649

HK$714 total

20 Sept - 21 Sept

includes taxes & fees

9.2/10 Wonderful! (1,575 reviews)

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

HK$642

HK$730 total

6 Sept - 7 Sept

includes taxes & fees

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

HK$641

HK$815 total

3 Sept - 4 Sept

includes taxes & fees

9/10 Wonderful! (1,011 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

HK$793

HK$880 total

5 Sept - 6 Sept

includes taxes & fees

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

161 Sha Ln Spartanburg SC

HK$804

HK$893 total

13 Sept - 14 Sept

includes taxes & fees

8.6/10 Excellent! (1,000 reviews)

Hotels in Upstate South Carolina with star-rating

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Car hire in Avis 3901 Quebec St

Things to do in Upstate South Carolina

Upstate South Carolina hotels from HK$489

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Tru by Hilton Spartanburg

2. Four Points by Sheraton Spartanburg

3. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

4. Comfort Suites At WestGate Mall

5. Best Western Spartanburg I-26

6. Hilton Garden Inn Spartanburg

7. Home2 Suites by Hilton Duncan

8. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

9. Comfort Suites Greenville Airport

10. Embassy Suites Greenville Golf Resort & Conference Center

11. Best Western Plus Greenville I-385 Inn & Suites

12. Courtyard by Marriott Greenville Mauldin

13. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

14. Hampton Inn & Suites Greenville Airport, SC

15. Spartanburg Marriott

16. Fairfield Inn & Suites by Marriott Greenville Simpsonville

17. Best Western Plus Spartanburg

18. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

19. Comfort Inn & Suites Greer - Greenville

20. Best Western Spartanburg Northwest

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Carolina Camp Cedar

Greer Guest House < 1 Mi to Park & Downtown Area!

Mint House Greenville Downtown by Kasa

Landing Apartments - Lyman

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Carolina Landing RV Resort - Caravan Park

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greenwood Getaway w/ Furnished Patio & Lake View

8 Mi to Clemson: Peaceful Family Home w/ Yard

Steps to Lake Greenwood: Waterfront Gem w/ Patio

Stunning Lakefront Retreat w/ Dock Access!

9 Mi to Devils Fork State Park: Getaway w/ Porch!

Waterfront Lake Hartwell Vacation Rental w/ Dock!

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Bon Secours Wellness Arena

Greenville Convention Center

Memorial Stadium

BMW Performance Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Hilton Greenville

Spartanburg Marriott

Comfort Suites At WestGate Mall

Grand Bohemian Lodge Greenville, Autograph Collection

More cheap stays in Upstate South Carolina

Days Inn by Wyndham Greenville

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Lakeside Lodge Clemson

Best Western Plus Clemson Hotel & Conference Center

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia

Go further with the Expedia app