Best Depew Hotels in 2026 - Fully Refundable Options

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Our top choices for Depew hotels

A hotel room with a bed, desk, and a large mirror with built-in lighting.

A large industrial building with a silo-like structure and a tower on top, surrounded by calm water with several small boats.

A lobby area with a vending machine, snack shelves, seating, and a reception desk.

A gym with treadmills, exercise bikes, and a mirrored wall.

1. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Buffalo

Nadine

HK$1,027

HK$1,168 total

includes taxes & fees

13 Sept - 14 Sept

A hotel room with a bed, a sofa, a desk with a chair, a television, and a minibar.

A hotel room with two beds, a sofa, a table, and a lamp.

A spacious dining area with multiple wooden tables and chairs, a kitchen area with a counter and appliances, and a tiled ceiling with a grid pattern.

A spacious lobby with a staircase, a reception desk, and a vending machine.

2. Sleep Inn & Suites Buffalo Airport

Buffalo

Stephanie

HK$548

HK$624 total

includes taxes & fees

21 Sept - 22 Sept

An indoor swimming pool with clear water, lounge chairs, and a lifeguard stand.

A modern dining area with yellow chairs, wooden tables, and a central counter with a coffee machine.

A modern hotel lobby with a blue accent wall, a reception desk, a sofa, a chair, and a coffee table.

A gym with a bench, dumbbells, and a treadmill.

3. Comfort Inn & Suites Buffalo Airport

Buffalo

Sarah

HK$826

HK$940 total

includes taxes & fees

30 Sept - 1 Oct

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern indoor space with a foosball table, seating areas, a mural, and a television screen.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

A modern lounge area with seating, tables, and hanging chairs.

4. Tru by Hilton Williamsville Buffalo Airport

Buffalo

Lachelle

HK$993

HK$1,129 total

includes taxes & fees

5 Oct - 6 Oct

A bar area with multiple stools, a counter, and TVs displaying sports.

A hotel room with a beige sofa, a wooden coffee table, a TV, and a bed with a wooden headboard.

A gym with treadmills, elliptical machines, and weightlifting equipment.

A hotel with a covered entrance, stone pillars, and a well-lit facade.

5. Buffalo Airport Hotel

Buffalo

Raihanul

HK$690

HK$785 total

includes taxes & fees

9 Sept - 10 Sept

A pool area with a hot tub, lounge chairs, and a lifeguard chair.

A modern hotel lobby with a central bar area, seating arrangements, and pendant lighting.

A modern hotel lobby with a beige sofa, green armchairs, a dining area, and a kitchen area with a refrigerator stocked with beverages.

6. Fairfield Inn & Suites by Marriott Buffalo Airport

Buffalo

Lisa

HK$1,122

HK$1,276 total

includes taxes & fees

28 Sept - 29 Sept

A room with two blue armchairs, a green armchair, and a woven ottoman. A large landscape painting is on the wall.

A hotel entrance with a glass door, stone facade, and a covered walkway.

A La Quinta Inn with a red and white exterior, a covered entrance, and a parking lot with several cars.

7. La Quinta Inn by Wyndham Buffalo Airport

Buffalo

Dion

HK$606

HK$689 total

includes taxes & fees

13 Sept - 14 Sept

A hotel pool area with a hot tub, lounge chairs, and a seating area with tables.

A modern bar area with a central island, bar stools, and a menu display.

A Courtyard by Marriott hotel with a covered entrance, brick facade, and multiple windows.

An outdoor patio area with a stone fire pit surrounded by wicker furniture and cushions.

8. Courtyard Buffalo Airport

Buffalo

Juan

HK$1,226

HK$1,395 total

includes taxes & fees

20 Sept - 21 Sept

A hotel lobby with a bar area, seating arrangements, and large windows providing natural light.

A Hampton Inn & Suites with a clear entrance, a covered parking area, and a brick facade.

A snack bar with refrigerated drinks, chips, and cookies.

9. Hampton Inn & Suites Buffalo Airport

Buffalo

Carmen

HK$1,022

HK$1,163 total

includes taxes & fees

28 Sept - 29 Sept

A patio area with a fire pit, outdoor furniture, and a pergola.

A modern hotel lobby with a reception desk, seating area, and a fireplace.

An indoor swimming pool with lounge chairs and umbrellas, surrounded by walls with windows and doors.

A multi-story hotel with a prominent entrance, well-maintained landscaping, and a clear view of the hotel's name.

10. Homewood Suites by Hilton Buffalo Airport

Buffalo

Rebeca

HK$1,048

HK$1,193 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with a central island, wooden cabinets, and a bar area with stools.

A modern hotel with a flat roof, large windows, and a covered entrance.

An outdoor patio with a round table, chairs, a cushioned seating area, and a barbecue grill.

A modern hotel lobby with a curved seating area, a flat-screen TV, and a dining area.

11. Springhill Suites Buffalo Airport

Buffalo

Matthias

HK$1,051

HK$1,196 total

includes taxes & fees

28 Sept - 29 Sept

A spacious lobby with a central seating area, a shop in the background, and potted plants along the walkway.

A modern bar area with a long counter, multiple seating options, and a unique ceiling design.

A Hilton Garden Inn hotel with a well-lit entrance, outdoor seating area, and landscaped garden.

An outdoor patio with a fire pit, seating, and string lights.

12. Hilton Garden Inn Buffalo Airport

Buffalo

Randol

HK$1,215

HK$1,382 total

includes taxes & fees

20 Sept - 21 Sept

A modern indoor seating area with tables and chairs, a sofa with cushions, and hanging pendant lights.

An indoor swimming pool with tiled flooring, seating areas, and potted plants.

A hotel reception area with a reception desk, a 'Hilton Honors' sign, a 'HOME 2' sign, a 'really cold' and 'cold' sign above a refrigerator, and a shelf with snacks.

13. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

Danielle

HK$1,215

HK$1,382 total

includes taxes & fees

20 Sept - 21 Sept

An outdoor seating area with orange chairs and tables, a covered area with umbrellas, and a building entrance with glass doors and interior lighting.

A modern hotel with a prominent 'Aloft' sign, large windows, and a well-lit entrance.

A modern cafe with a wooden counter, clear menu boards, and a variety of food and drink dispensers.

14. Aloft by Marriott Buffalo Airport

Buffalo

Gene

HK$1,157

HK$1,316 total

includes taxes & fees

5 Oct - 6 Oct

An indoor swimming pool with a water fountain, surrounded by greenery and modern architecture with a glass ceiling.

A hotel room with a bed, a TV mounted on the wall, a small table with a vase and candles, a chair, and a view of the city at night.

A hotel room with a large bed, a chair, a desk, and a view of the outdoors.

A hotel room with two beds, a desk with a television, and a view of the outdoors.

15. M Hotel Buffalo

Buffalo

Elizabeth

HK$809

HK$920 total

includes taxes & fees

14 Sept - 15 Sept

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A multi-story hotel with a stone facade, a prominent entrance with a metal archway, and a parking lot in front.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

A bar area with leather barstools, a bar counter, and a television screen.

16. The Delavan Hotel & Spa

Bowmansville

JACK

HK$845

HK$961 total

includes taxes & fees

8 Oct - 9 Oct

A Holiday Inn Express building with a covered entrance, a flag, and a sign indicating the address.

A hotel room with a large bed, a desk with a flat-screen TV, a sofa, a lamp, and a window with curtains.

A large indoor swimming pool with a curved edge, a lounge area with a sofa, and a door leading to another room.

A modern hotel lobby with a circular glass table surrounded by chairs, a bar area, and seating with orange cushions.

17. Holiday Inn Express Cheektowaga North East by IHG

Buffalo

Nadia

HK$1,058

HK$1,236 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a wooden floor, a reception desk, a large flat-screen TV, a blue sofa, and a staircase.

A hotel room with a wooden desk, a television, a bed with white bedding, and a window with blinds.

A multi-story brick building with a central entrance and a flagpole.

A spacious lobby with a stone fireplace, blue sofas, and a large mirror.

18. Extended Stay America Suites - Buffalo - Airport

Buffalo

michael

HK$620

HK$723 total

includes taxes & fees

29 Sept - 30 Sept

A Hampton Inn hotel with a modern facade, large windows, and a well-maintained parking lot.

An indoor swimming pool with blue and yellow lounge chairs, large windows, and a tiled floor.

A kitchen area with a chalkboard wall displaying cooking instructions and a sign promoting waffles.

An outdoor patio with a table and chairs, a blue sofa, and a large umbrella.

19. Hampton Inn Buffalo-Airport / Galleria Mall

Buffalo

Oscar

HK$1,132

HK$1,287 total

includes taxes & fees

20 Sept - 21 Sept

A pool area with clear blue water, a diving board, and several lounge chairs.

A modern hotel lobby with a kitchen area, a seating area, and a refrigerator stocked with beverages.

A modern conference room with tables and chairs, large windows, and a carpeted floor.

An outdoor patio area with wicker chairs, round tables, and a barbecue grill.

20. TownePlace Suites Buffalo Airport

Buffalo

Doug

HK$1,228

HK$1,433 total

includes taxes & fees

29 Sept - 30 Sept

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Top Depew Hotel Reviews

Wyndham Garden Buffalo Downtown

10/10 Excellent

"The staff was very helpful and the rooms were very clean. We loved the valet parking and the shuttle bus."

Microtel Inn & Suites by Wyndham Niagara Falls

8/10 Good

"Excelente desayuno es muy completo. Lo que no me gustó un poco es habitación se paga de lujo como decía pero en tamaño no es tan espaciosa como suelen ser habitaciones de lujo. Parecía una normal con jacuzzi"

Garden Place Hotel

10/10 Excellent

"Perfect hotel for family and you self if that is the case. Love stay in here ."

La Quinta Inn & Suites by Wyndham Buffalo Amherst

8/10 Good

"Clean and neat room"

Comfort Inn & Suites Buffalo Airport

10/10 Excellent

"This was a wonderful and clean hotel for my stay in buffalo. I enjoyed it and felt really clean."

Buffalo Airport Hotel

10/10 Excellent

"Great hotel for a quick stop."

Hyatt Place Buffalo/Amherst

10/10 Excellent

"Very friendly & helpful staff. Will definitely be back!! Very clean as well."

Comfort Inn University

10/10 Excellent

"Amazing stuff and the room was so clean"

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

8/10 Good

"Overall nice"

Hotels in Depew with star-rating

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Buffalo Airport Hotel and Hyatt Regency Buffalo / Hotel and Conference Center. See all available top hotels, or vacation rentals in Depew.

What are some of the best holiday rentals that Depew has to offer?

HTR Niagara: This holiday home rental outside of Depew is on the riverwalk, and equipped with air conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities such as a coffee maker and free parking are also available for your convenience. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

What are some accommodation options with pools in Depew?

M Hotel Buffalo: Hotel, 4-minute walk from Walden Galleria Mall. Features buffet, an indoor pool and free self parking. Hyatt Regency Buffalo / Hotel and Conference Center and Holiday Inn Express Grand Island - Niagara Falls by IHG are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. A top sight in the area is Highmark Stadium. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.

What should I see while I'm in Depew?

Highmark Stadium is a notable place to visit in the area. You'll also find Walden Galleria Mall and Glen Falls in the area. Take a look at what more there is to see and do in Expedia's Depew guide.

How can I get around Depew?

If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the seasonal weather like in Depew?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

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Depew hotels

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Depew

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Depew hotels

1. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2. Sleep Inn & Suites Buffalo Airport

3. Comfort Inn & Suites Buffalo Airport

4. Tru by Hilton Williamsville Buffalo Airport

5. Buffalo Airport Hotel

6. Fairfield Inn & Suites by Marriott Buffalo Airport

7. La Quinta Inn by Wyndham Buffalo Airport

8. Courtyard Buffalo Airport

9. Hampton Inn & Suites Buffalo Airport

10. Homewood Suites by Hilton Buffalo Airport

11. Springhill Suites Buffalo Airport

12. Hilton Garden Inn Buffalo Airport

13. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

14. Aloft by Marriott Buffalo Airport

15. M Hotel Buffalo

16. The Delavan Hotel & Spa

17. Holiday Inn Express Cheektowaga North East by IHG

18. Extended Stay America Suites - Buffalo - Airport

19. Hampton Inn Buffalo-Airport / Galleria Mall

20. TownePlace Suites Buffalo Airport

Top Depew Hotel Reviews

Wyndham Garden Buffalo Downtown

Microtel Inn & Suites by Wyndham Niagara Falls

Garden Place Hotel

La Quinta Inn & Suites by Wyndham Buffalo Amherst

Comfort Inn & Suites Buffalo Airport

Buffalo Airport Hotel

Hyatt Place Buffalo/Amherst

Comfort Inn University

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

Hotels in Depew with star-rating

Frequently asked questions

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