Best Depew Hotels in 2026 from HK$441 - Fully Refundable Options

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Go beyond your typical stay in Depew

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Our top choices for Depew hotels

1. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Buffalo

Nadine

HK$1,027

HK$1,168 total

includes taxes & fees

13 Sept - 14 Sept

2. Sleep Inn & Suites Buffalo Airport

Buffalo

Stephanie

HK$548

HK$624 total

includes taxes & fees

21 Sept - 22 Sept

3. Comfort Inn & Suites Buffalo Airport

Buffalo

Sarah

HK$826

HK$940 total

includes taxes & fees

30 Sept - 1 Oct

4. Tru by Hilton Williamsville Buffalo Airport

Buffalo

Lachelle

HK$993

HK$1,129 total

includes taxes & fees

5 Oct - 6 Oct

5. Buffalo Airport Hotel

Buffalo

Christopher

HK$690

HK$785 total

includes taxes & fees

9 Sept - 10 Sept

6. Fairfield Inn & Suites by Marriott Buffalo Airport

Buffalo

Lisa

HK$1,122

HK$1,276 total

includes taxes & fees

28 Sept - 29 Sept

7. La Quinta Inn by Wyndham Buffalo Airport

Buffalo

Dion

HK$606

HK$689 total

includes taxes & fees

21 Sept - 22 Sept

8. Courtyard Buffalo Airport

Buffalo

Juan

HK$1,226

HK$1,395 total

includes taxes & fees

20 Sept - 21 Sept

9. Hampton Inn & Suites Buffalo Airport

Buffalo

Carmen

HK$1,022

HK$1,163 total

includes taxes & fees

28 Sept - 29 Sept

10. Homewood Suites by Hilton Buffalo Airport

Buffalo

Rebeca

HK$1,048

HK$1,193 total

includes taxes & fees

20 Sept - 21 Sept

11. Springhill Suites Buffalo Airport

Buffalo

Matthias

HK$1,051

HK$1,196 total

includes taxes & fees

28 Sept - 29 Sept

12. Hilton Garden Inn Buffalo Airport

Buffalo

Randol

HK$1,215

HK$1,382 total

includes taxes & fees

20 Sept - 21 Sept

13. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

Buffalo

Danielle

HK$1,215

HK$1,382 total

includes taxes & fees

20 Sept - 21 Sept

14. Aloft by Marriott Buffalo Airport

Buffalo

Gene

HK$1,157

HK$1,316 total

includes taxes & fees

5 Oct - 6 Oct

15. M Hotel Buffalo

Buffalo

Elizabeth

HK$809

HK$920 total

includes taxes & fees

13 Sept - 14 Sept

16. The Delavan Hotel & Spa

Bowmansville

JACK

HK$845

HK$961 total

includes taxes & fees

8 Oct - 9 Oct

17. Holiday Inn Express Cheektowaga North East by IHG

Buffalo

Nadia

HK$1,058

HK$1,236 total

includes taxes & fees

13 Sept - 14 Sept

18. Extended Stay America Suites - Buffalo - Airport

Buffalo

michael

HK$620

HK$723 total

includes taxes & fees

29 Sept - 30 Sept

19. Hampton Inn Buffalo-Airport / Galleria Mall

Buffalo

Oscar

HK$1,132

HK$1,287 total

includes taxes & fees

20 Sept - 21 Sept

20. TownePlace Suites Buffalo Airport

Buffalo

Doug

HK$1,122

HK$1,310 total

includes taxes & fees

28 Sept - 29 Sept

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Top Depew Hotel Reviews

M Hotel Buffalo

8/10 Good

"It was value for money"

Best Western Summit Inn

8/10 Good

"good"

Buffalo Airport Hotel

10/10 Excellent

"Nice hotel"

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

10/10 Excellent

"Me encanto la recamara fue la que medieron me encanto el lugar todo perfecto"

Fairbridge Inn Express Buffalo Airport Williamsville

10/10 Excellent

"It was good. I just didn’t get my deposit back"

Microtel Inn & Suites by Wyndham Niagara Falls

8/10 Good

"Excelente desayuno es muy completo. Lo que no me gustó un poco es habitación se paga de lujo como decía pero en tamaño no es tan espaciosa como suelen ser habitaciones de lujo. Parecía una normal con jacuzzi"

Garden Place Hotel

10/10 Excellent

"Perfect hotel for family and you self if that is the case. Love stay in here ."

La Quinta Inn & Suites by Wyndham Buffalo Amherst

8/10 Good

"Clean and neat room"

Comfort Inn & Suites Buffalo Airport

10/10 Excellent

"This was a wonderful and clean hotel for my stay in buffalo. I enjoyed it and felt really clean."

More cheap stays in Depew

Fairbridge Inn Express Buffalo Airport Williamsville

7200 Transit Road Buffalo NY

HK$388

HK$441 total

1 Oct - 2 Oct

includes taxes & fees

4.8/10 (1,118 reviews)

Sleep Inn & Suites Buffalo Airport

100 Holtz Dr Buffalo NY

HK$548

HK$624 total

21 Sept - 22 Sept

includes taxes & fees

Motel 6 Amherst, NY - Buffalo

4400 Maple Rd Buffalo NY

HK$549

HK$624 total

13 Sept - 14 Sept

includes taxes & fees

Best Western Summit Inn

9500 Niagara Falls Blvd Niagara Falls NY

HK$706

HK$804 total

10 Sept - 11 Sept

includes taxes & fees

8.6/10 Excellent! (1,600 reviews)

Comfort Inn University

1 Flint Rd Buffalo NY

HK$791

HK$900 total

20 Sept - 21 Sept

includes taxes & fees

8.2/10 Very good! (1,473 reviews)

Holiday Inn Express Grand Island - Niagara Falls by IHG

2761 Long Road Grand Island NY

HK$813

HK$925 total

6 Oct - 7 Oct

includes taxes & fees

Hotels in Depew with star-rating

Frequently asked questions

What's the best place for a stay in Depew?

Located 2.9 mi (4.6 km) from the heart of Depew, M Hotel Buffalo is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Buffalo Airport Hotel and Hyatt Regency Buffalo / Hotel and Conference Center. See all available top hotels, or vacation rentals in Depew.

What are some of the best holiday rentals that Depew has to offer?

HTR Niagara: This holiday home rental outside of Depew is on the riverwalk, and equipped with air conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities such as a coffee maker and free parking are also available for your convenience. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

What are some accommodation options with pools in Depew?

M Hotel Buffalo: Hotel, 4-minute walk from Walden Galleria Mall. Features buffet, an indoor pool and free self parking. Hyatt Regency Buffalo / Hotel and Conference Center and Holiday Inn Express Grand Island - Niagara Falls by IHG are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. A top sight in the area is Highmark Stadium. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.

What should I see while I'm in Depew?

Highmark Stadium is a notable place to visit in the area. You'll also find Walden Galleria Mall and Glen Falls in the area. Take a look at what more there is to see and do in Expedia's Depew guide.

How can I get around Depew?

If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the seasonal weather like in Depew?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

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Depew hotels from HK$441

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Depew

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Depew hotels

1. Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2. Sleep Inn & Suites Buffalo Airport

3. Comfort Inn & Suites Buffalo Airport

4. Tru by Hilton Williamsville Buffalo Airport

5. Buffalo Airport Hotel

6. Fairfield Inn & Suites by Marriott Buffalo Airport

7. La Quinta Inn by Wyndham Buffalo Airport

8. Courtyard Buffalo Airport

9. Hampton Inn & Suites Buffalo Airport

10. Homewood Suites by Hilton Buffalo Airport

11. Springhill Suites Buffalo Airport

12. Hilton Garden Inn Buffalo Airport

13. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

14. Aloft by Marriott Buffalo Airport

15. M Hotel Buffalo

16. The Delavan Hotel & Spa

17. Holiday Inn Express Cheektowaga North East by IHG

18. Extended Stay America Suites - Buffalo - Airport

19. Hampton Inn Buffalo-Airport / Galleria Mall

20. TownePlace Suites Buffalo Airport

Top Depew Hotel Reviews

M Hotel Buffalo

Best Western Summit Inn

Buffalo Airport Hotel

Days Inn & Suites by Wyndham Niagara Falls/Buffalo

Fairbridge Inn Express Buffalo Airport Williamsville

Microtel Inn & Suites by Wyndham Niagara Falls

Garden Place Hotel

La Quinta Inn & Suites by Wyndham Buffalo Amherst

Comfort Inn & Suites Buffalo Airport

More cheap stays in Depew

Fairbridge Inn Express Buffalo Airport Williamsville

Sleep Inn & Suites Buffalo Airport

Motel 6 Amherst, NY - Buffalo

Best Western Summit Inn

Comfort Inn University

Holiday Inn Express Grand Island - Niagara Falls by IHG

Hotels in Depew with star-rating

Frequently asked questions

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