Rochester Mayo Clinic Hotels

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Tonight
21 Dec - 22 Dec
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22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Mayo Clinic hotels

Property amenity
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (481)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is HK$988
HK$1,138 total
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (545)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is HK$1,334
HK$1,535 total
includes taxes & fees
27 Dec - 28 Dec
Hilton Rochester Mayo Clinic Area
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (677)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is HK$693
HK$797 total
includes taxes & fees
29 Dec - 30 Dec
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Terrace/patio
The Berkman

The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (371)
"Staff was great, as was the room."
United States
Scott
The price is HK$1,085
HK$1,262 total
includes taxes & fees
24 Dec - 25 Dec
The Berkman
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (882)
"Great stay,clean and friendly"
United States
Janet
The price is HK$887
HK$1,021 total
includes taxes & fees
27 Dec - 28 Dec
Home2 Suites by Hilton Rochester Mayo Clinic Area
BBQ/picnic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (250)
"Very nice motel "
United States
Jim
The price is HK$996
HK$1,147 total
includes taxes & fees
25 Dec - 26 Dec
Residence Inn by Marriott Rochester Mayo Clinic Area South
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (962)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is HK$848
HK$992 total
includes taxes & fees
26 Dec - 27 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (421)
"Early check in was definitely a plus since I flew from out of town. "
United States
Humberto
The price is HK$965
HK$1,126 total
includes taxes & fees
26 Dec - 27 Dec
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1004)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is HK$1,004
HK$1,156 total
includes taxes & fees
22 Dec - 23 Dec
Hyatt House Rochester/Mayo Clinic Area
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is HK$1,089
HK$1,253 total
includes taxes & fees
27 Dec - 28 Dec
Broadway Plaza, Trademark Collection by Wyndham
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (769)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is HK$654
HK$752 total
includes taxes & fees
23 Dec - 24 Dec
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (477)
"Clean room, breakfast selection"
United States
Sonya
The price is HK$759
HK$874 total
includes taxes & fees
28 Dec - 29 Dec
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Exterior
Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.2 out of 10, Wonderful, (454)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is HK$755
HK$869 total
includes taxes & fees
5 Jan - 6 Jan 2026
Candlewood Suites Rochester Mayo Clinic Area by IHG
Front of property
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (693)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
The price is HK$1,206
HK$1,458 total
includes taxes & fees
9 Jan - 10 Jan 2026
Aspen Suites
Terrace/patio
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1008)
"We had a wonderful stay!"
United States
Sarah
The price is HK$640
HK$737 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Rochester-South
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (897)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is HK$514
HK$592 total
includes taxes & fees
3 Jan - 4 Jan 2026
Econo Lodge Mayo Clinic Area
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (891)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is HK$622
HK$717 total
includes taxes & fees
25 Dec - 26 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (853)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is HK$833
HK$959 total
includes taxes & fees
27 Dec - 28 Dec
Hilton Garden Inn Rochester Downtown, MN
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1006)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is HK$875
HK$1,008 total
includes taxes & fees
22 Dec - 23 Dec
Brentwood Inn & Suites
Free daily full breakfast
Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
2.6 km from Mayo Clinic
8.8 out of 10, Excellent, (830)
"Very clean and so helpful "
United States
Mark
The price is HK$504
HK$588 total
includes taxes & fees
3 Jan - 4 Jan 2026
Quality Inn & Suites Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Hotel Reviews

Hotels near other Mayo Clinic attractions

Soldiers Field Veterans Memorial

4.5/5 (30 reviews)
You can learn about the history of Rochester when you stop by Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.
See properties

Plummer Building

You can find out about the history of Rochester when you stop by Plummer Building.
See properties

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 157 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.
How many hotels should I expect to find near Mayo Clinic?
Expedia has 157 hotels and other accommodation options within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Mayo Clinic.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

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