Photo by Mark Wilcoxson

Clarksville 4 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Clarksville 4 Star Hotels

This weekend
Next weekend

Our top choices for Clarksville 4-star hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3881)
"Great place to stay! "
United States
Rochelle
The price is HK$1,037
HK$1,220 total
includes taxes & fees
30 Dec - 31 Dec
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1739)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is HK$1,300
HK$1,530 total
includes taxes & fees
4 Jan - 5 Jan 2026
Omni Louisville Hotel

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1121)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is HK$949
HK$1,116 total
includes taxes & fees
11 Jan - 12 Jan 2026
Embassy Suites Louisville Downtown

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
Louisville
9.4 out of 10, Exceptional, (1714)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1158)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The Brown Hotel

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1019)
"Great location and accommodations."
United States
Steve
The price is HK$988
HK$1,162 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Genevieve part of JdV by Hyatt

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is HK$1,081
HK$1,311 total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is HK$988
HK$1,162 total
includes taxes & fees
27 Dec - 28 Dec
Hyatt Regency Louisville

Marriott Louisville East

Marriott Louisville East
4.0 star property
Jeffersontown
9.0 out of 10, Wonderful, (1000)
"Very nice hotel, rooms were clean and comfortable, breakfast is great!"
United States
Miguel
The price is HK$853
HK$1,003 total
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott Louisville East

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1005)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is HK$1,127
HK$1,326 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Grady

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is HK$1,304
HK$1,534 total
includes taxes & fees
18 Jan - 19 Jan 2026
Louisville Marriott Downtown

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is HK$1,362
HK$1,602 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Distil, Autograph Collection

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (56)
"Amazing property! Best hotel in Louisville! Will be staying there again!"
United States
Norman
The price is HK$1,309
HK$1,540 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1001)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is HK$1,073
HK$1,263 total
includes taxes & fees
27 Dec - 28 Dec
Seelbach Hilton Louisville Downtown

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is HK$899
HK$1,450 total
includes taxes & fees
8 Jan - 9 Jan 2026
Stellar Suites

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (649)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is HK$707
HK$799 total
includes taxes & fees
28 Dec - 29 Dec
The Pepin Mansion Historic B&B

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is HK$490
HK$1,471 total
includes taxes & fees
18 Jan - 19 Jan 2026
CozySuites at Nulu

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
The price is HK$1,147
HK$1,297 total
includes taxes & fees
26 Dec - 27 Dec
stayAPT Suites Louisville North-Clarksville

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is HK$1,283
HK$1,878 total
includes taxes & fees
28 Dec - 29 Dec
The Reserve on Main

Inn at St James Court

Inn at St James Court
4.0 star property
Old Louisville
9.8 out of 10, Exceptional, (131)
"Lovely Victorian house in a gorgeous and convenient gorgeous neighborhood. "
United States
marcia
Inn at St James Court
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clarksville.
Louisville Bourbon Inn

Louisville Bourbon Inn

1332 S 4th St Louisville KY
The price is HK$2,061 per night from 28 Dec to 29 Dec
HK$2,061
HK$2,392 total
28 Dec - 29 Dec
includes taxes & fees
10/10 Exceptional! (20 reviews)
Still don't see what you're looking for?
See all properties in Clarksville.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Clarksville

Stroll along the Ohio River at the Falls of the Ohio State Park, where fossil beds and hiking trails await. Catch a show at the historic Clarksville Little Theatre or browse unique shops in the charming city centre area.

View of Louisville from the Falls of the Ohio at Golden Hour. #BVSblue
Photo by Eric O
Open Photo by Eric O

Top Clarksville Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Clarksville?
Look forward to 4-star hotel comfort at Galt House Hotel Trademark Collection by Wyndham. Rated highly by many Expedia guests, it offers massage services and concierge services. Also have a look at 21c Museum Hotel Louisville. Beauty services and concierge services help make this getaway another in-demand pick in Clarksville.
How much does it cost to stay in a 4-star hotel in Clarksville?
With Expedia's handy filter tool, locking in a superb deal on a 4-star hotel in Clarksville just got easier. Start by keying in your chosen travel dates and length of your trip. Then sort the results by price and choose a property that best fits your style and budget.

  • Search for the lowest price from HK$2,392

What's the difference between 5-star and 4-star hotels in Clarksville?
Offering a friendly guest experience and upscale surroundings, 4-star hotels are a fabulous option for your Clarksville trip. These kinds of accommodation generally feature loads of handy amenities that make it simple to kick back and relax — think pillowtop mattresses, restaurants and gyms. Or live the high life at a 5-star hotel designed to pamper with luxury perks and amenities. 24-hour front desk, premium toiletries and world-class dining are typically featured at these swanky retreats.

Explore a world of travel with Expedia