Best Upstate South Carolina Hotels in 2026 from HK$565 - Fully Refundable Options

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

A modern lobby with a reception desk, seating area, and a television screen.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

1. Best Western Spartanburg I-26

Spartanburg

Catherine

HK$727

HK$807 total

includes taxes & fees

27 Sept - 28 Sept

An outdoor seating area with sofas, a fire pit, and string lights.

A modern interior with hanging chairs, tables, and a view of the parking lot.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

2. Tru by Hilton Spartanburg

Spartanburg

Jeremy

HK$830

HK$921 total

includes taxes & fees

4 Oct - 5 Oct

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

3. Four Points by Sheraton Spartanburg

Spartanburg

Travis

HK$840

HK$932 total

includes taxes & fees

27 Sept - 28 Sept

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

A spacious lobby with a bar area, seating, and large windows.

A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

4. Hilton Garden Inn Spartanburg

Spartanburg

Stan

HK$1,029

HK$1,142 total

includes taxes & fees

4 Oct - 5 Oct

A modern restaurant with a brick wall, wooden ceiling beams, and a central seating area with tables and chairs.

An outdoor patio with a fire pit, seating area, and a TV.

A hallway with a wooden wall, a large abstract sculpture, and patterned flooring.

An outdoor pool area with seating and umbrellas.

5. Hampton Inn Greer Greenville, SC

Greer

Teresa

HK$1,129

HK$1,231 total

includes taxes & fees

17 Sept - 18 Sept

A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

A food service counter with a sign that reads "EXPRESS START".

A large indoor swimming pool with a diving board, multiple doors, and seating areas.

6. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

Michael

HK$805

HK$893 total

includes taxes & fees

20 Sept - 21 Sept

A modern interior with a fireplace, seating, and a wooden wall.

A modern living room with a flat-screen TV, a brown sofa, a small table, and a blue armchair.

A reception desk with a 'Welcome to Hampton' sign and a cityscape photograph.

A modern interior with seating areas, tables, a flat-screen TV, and a fireplace.

7. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

Kathy

HK$753

HK$835 total

includes taxes & fees

5 Oct - 6 Oct

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A gym with treadmills, elliptical machines, and weight machines.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

8. Comfort Suites At WestGate Mall

Spartanburg

Savannah

HK$715

HK$794 total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass facade and a well-lit exterior.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

9. Home2 Suites by Hilton Duncan

Duncan

Lilia

HK$926

HK$1,028 total

includes taxes & fees

11 Oct - 12 Oct

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A multi-level atrium with a modern design, featuring a central open space with tiered seating and tables, surrounded by balconies with greenery.

An outdoor patio with a stone fire pit, wicker chairs, and a pergola structure.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

10. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Pedro

HK$804

HK$911 total

includes taxes & fees

27 Sept - 28 Sept

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern living room with a fireplace, seating area, and a kitchen in the background.

A swimming pool with lounge chairs and a no diving sign.

A multi-story hotel with a central courtyard, a pool, and a parking area.

11. Comfort Suites Greenville Airport

Greenville

Ryan

HK$730

HK$827 total

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen with a large wooden table and brown leather chairs, a microwave, and a coffee machine.

A compact kitchen with white cabinets, a microwave, a sink, and a flat-screen TV.

A hotel room with two beds, a wooden headboard, a nightstand, a lamp, and a window with a view.

12. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

Duncan

Celeste

HK$628

HK$697 total

includes taxes & fees

16 Oct - 17 Oct

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A lobby with a stone fireplace, sofas, a TV mounted on the wall, and a bar area in the background.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

13. Spartanburg Marriott

Spartanburg

Sarah

HK$926

HK$1,058 total

includes taxes & fees

4 Oct - 5 Oct

A modern living room with a fireplace, two sofas, and a coffee table.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

14. Best Western Spartanburg Northwest

Spartanburg

Darius

HK$760

HK$861 total

includes taxes & fees

20 Sept - 21 Sept

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A hotel lobby with a reception desk, a patterned carpet, and a large abstract wall art piece.

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and a brick pillar.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

15. Hampton Inn & Suites Greenville Airport, SC

Greenville

Kristina

HK$821

HK$931 total

includes taxes & fees

27 Sept - 28 Sept

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

16. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Michael

HK$863

HK$958 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with a central island, bar stools, and pendant lighting.

A large indoor swimming pool with clear water, surrounded by lounge chairs and tables, and equipped with safety signage.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

MARLON

HK$940

HK$1,043 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a stone fire feature, seating, and a view of the city skyline.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped flower beds.

A modern hotel lobby with a bar area, seating, and a large window providing natural light.

A modern bar area with a wooden counter, a digital menu board, and a variety of liquor bottles.

18. Courtyard by Marriott Greenville Mauldin

Greenville

Leticia

HK$933

HK$1,027 total

includes taxes & fees

27 Sept - 28 Sept

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

19. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Ryan

HK$596

HK$656 total

includes taxes & fees

4 Oct - 5 Oct

A spacious lobby with modern furniture, a chandelier, and potted plants.

An outdoor seating area with tables and chairs, potted plants, and a modern building facade.

20. Hilton Greenville

Greenville

Edward

HK$894

HK$1,013 total

includes taxes & fees

27 Sept - 28 Sept

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Holiday Rentals in Upstate South Carolina

Apartment

A spacious living room with a stone fireplace, wooden beams, and a chandelier.

A modern kitchen with white cabinetry, dark blue walls, and a patterned floor.

A multi-story residential building with balconies, a stone archway entrance, and a sign indicating it is part of Century Park at Taft Community.

A modern kitchen with dark cabinetry, a stainless steel range, and a granite countertop.

Landing Apartments Greer - Sugar Creek

Greer

"The apartment was clean. Excellent value for stay. Amenities were great. Will book again!"

Cabin

A spacious porch with wooden flooring, a dining area with a table and chairs, and a view of the surrounding landscape.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A swimming pool with lounge chairs and a covered area with tables and chairs.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Aparthotel

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

stayAPT Suites Greenville-Haywood Mall

Greenville

"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."

Cabin

A wooden cabin bedroom with a large window, a bed, a bedside table with a lantern, and a heater.

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A cozy living room with a sofa, two side tables, a coffee table, and a patterned rug.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Aparthotel

A modern building with outdoor seating and a garden.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"The unit was very clean, and I stay here whenever I'm in Greenville."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A cozy living room with a dining table, sofas, and a chandelier.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A rustic cabin with a porch, wooden steps, and a picnic table.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

A modern kitchen with white cabinets, stainless steel appliances, and a patterned rug.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

A dining area with a round table and six chairs, a kitchen with white cabinets, and a window with blinds.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Apartment

A wooden gazebo with a roof, surrounded by trees, overlooking a lake.

A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

A cozy living room with a fireplace, leather armchair, and a large window.

A spacious living area with a high ceiling, wooden beams, a grey sofa, a brown leather chair, and a dining table with a plant.

Designer Retreat w/ Pool, Golf + Beach Access!

Salem

"Property is in a great community, and it was very clean and beautifully decorated."

Cottage

A modern kitchen with blue cabinets, a central island, and a spiral staircase leading to an upper level.

A modern living room with a fireplace, a large TV, and a kitchen area with blue cabinets and a bar.

A two-story house with a covered porch, a small garden, and a view of a lake.

A modern kitchen with blue cabinets, stainless steel appliances, and a large island.

Greenwood Getaway w/ Furnished Patio & Lake View

Greenwood

"Wonderful stay and would definitely stay again! Reasonable price for the luxury place with everything that you could ask for in a rental. Close to restaurants and bars if that is your thing and right near the lake with beautiful views!! We loved our stay!"

Cottage

A covered porch with wooden railings and a table with chairs.

A kitchen with a dining area, a sliding glass door to a deck, and a ceiling fan.

A cabin with a wooden deck, a gravel driveway, and a forested backdrop.

A cozy living room with a sectional sofa, a wooden chair, a coffee table, and a red and black patterned rug.

9 Mi to Devils Fork State Park: Getaway w/ Porch!

Tamassee

"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Heritage Park and CCNB Amphitheatre.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Best Western Spartanburg I-26

10/10 Excellent

"The staff makes the difference."

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent

"Excellent breakfast. Nice pool. Very convenient location."

Hyatt Place Greenville/Haywood

8/10 Good

"Nice hotel for the price. Big rooms"

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"Room was clean and bed was comfortable. Breakfast was great! Best location in Clemson. Best value by far."

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent

"Room was clean, staff was very nice"

Grand Bohemian Lodge Greenville, Autograph Collection

8/10 Good

"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."

Mint House Greenville Downtown by Kasa

10/10 Excellent

"Parking was the only real issue I had because I arrived before I got the check-in email. Had I waited, i less if you’re gonna be playingt was perfectly clear what I needed to do. It was located in a very convenient place close to Falls Park. It was a spacious unit and everything was clean. Very pleased."

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC

HK$502

HK$565 total

17 Sept - 18 Sept

includes taxes & fees

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

HK$596

HK$656 total

4 Oct - 5 Oct

includes taxes & fees

9.2/10 Wonderful! (1,578 reviews)

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

HK$640

HK$727 total

4 Oct - 5 Oct

includes taxes & fees

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

HK$793

HK$881 total

23 Sept - 24 Sept

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

HK$827

HK$918 total

8 Oct - 9 Oct

includes taxes & fees

8.4/10 Very good! (1,001 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

HK$855

HK$1,061 total

20 Sept - 21 Sept

includes taxes & fees

Hotels in Upstate South Carolina with star-rating

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Car hire in Avis 3901 Quebec St

Things to do in Upstate South Carolina

Upstate South Carolina hotels from HK$565

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Best Western Spartanburg I-26

2. Tru by Hilton Spartanburg

3. Four Points by Sheraton Spartanburg

4. Hilton Garden Inn Spartanburg

5. Hampton Inn Greer Greenville, SC

6. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

7. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

8. Comfort Suites At WestGate Mall

9. Home2 Suites by Hilton Duncan

10. Embassy Suites Greenville Golf Resort & Conference Center

11. Comfort Suites Greenville Airport

12. Extended Stay America Premier Suites - Greenville - Spartanburg - I-85

13. Spartanburg Marriott

14. Best Western Spartanburg Northwest

15. Hampton Inn & Suites Greenville Airport, SC

16. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

17. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

18. Courtyard by Marriott Greenville Mauldin

19. Best Western Plus Greenville I-385 Inn & Suites

20. Hilton Greenville

Holiday Rentals in Upstate South Carolina

Landing Apartments Greer - Sugar Creek

Carolina Camp Cedar

stayAPT Suites Greenville-Haywood Mall

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Greer Guest House < 1 Mi to Park & Downtown Area!

The Station by Compo Hotels

Mint House Greenville Downtown by Kasa

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Designer Retreat w/ Pool, Golf + Beach Access!

Greenwood Getaway w/ Furnished Patio & Lake View

9 Mi to Devils Fork State Park: Getaway w/ Porch!

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Bon Secours Wellness Arena

Greenville Convention Center

Memorial Stadium

BMW Performance Center

Haywood Mall

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Best Western Spartanburg I-26

Best Western Plus Greenville I-385 Inn & Suites

Hyatt Place Greenville/Haywood

Comfort Inn & Suites Clemson - University Area

Embassy Suites Greenville Golf Resort & Conference Center

Grand Bohemian Lodge Greenville, Autograph Collection

Mint House Greenville Downtown by Kasa

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia

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