Best Upstate South Carolina Hotels in 2026 from HK$489 - Fully Refundable Options

A bench, a bicycle, and a lake surrounded by trees.

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

An outdoor seating area with sofas, a fire pit, and string lights.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

A modern interior with hanging chairs, tables, and a view of the parking lot.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

1. Tru by Hilton Spartanburg

Spartanburg

Anthony

HK$830

HK$921 total

includes taxes & fees

1 Nov - 2 Nov

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

A hotel entrance with a covered walkway, a landscaped area with trees, and a well-lit building facade.

A spacious lobby with a bar area, seating, and large windows.

2. Hilton Garden Inn Spartanburg

Spartanburg

Yuliya

HK$1,027

HK$1,140 total

includes taxes & fees

30 Oct - 31 Oct

A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.

A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.

A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.

3. AC Hotel by Marriott Spartanburg

Spartanburg

Willow

HK$1,326

HK$1,472 total

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with a reception desk, seating area, and a television screen.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

4. Best Western Spartanburg I-26

Spartanburg

Santhosh

HK$761

HK$844 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a central island, bar stools, and pendant lighting.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

A hotel lobby with a reception desk, seating area, and large windows.

5. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Melinda

HK$894

HK$993 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass facade and a well-lit exterior.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A vending machine area with snacks and beverages, and a display of green apples.

6. Home2 Suites by Hilton Duncan

Duncan

Marina

HK$961

HK$1,066 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a refrigerator stocked with beverages, and shelves with snacks.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

7. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

Joseph

HK$977

HK$1,099 total

includes taxes & fees

26 Oct - 27 Oct

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

An indoor swimming pool with lounge chairs and potted plants.

A modern living room with a dining table, chairs, a sofa, a television, and bookshelves.

A golf course with a pond, surrounded by trees and flowering bushes.

8. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Ethan

HK$830

HK$941 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A Hampton Inn & Suites hotel with a modern facade, a covered entrance, and a brick pillar.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

9. Hampton Inn & Suites Greenville Airport, SC

Greenville

Tina

HK$766

HK$868 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

An indoor swimming pool with clear water, a blue border, and a lifeguard station. There are lounge chairs and a covered seating area.

A vending area with various snack and drink options, including chips, sodas, and bottled water.

A Holiday Inn Express hotel with a covered entrance, brick facade, and large windows.

10. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Amy

HK$824

HK$915 total

includes taxes & fees

18 Oct - 19 Oct

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

A spacious lobby with a high ceiling, modern furniture, and large windows offering views of the outdoors.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

11. Four Points by Sheraton Spartanburg

Spartanburg

Elaine

HK$876

HK$972 total

includes taxes & fees

25 Oct - 26 Oct

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A gym with treadmills, elliptical machines, and weight machines.

12. Comfort Suites At WestGate Mall

Spartanburg

tara

HK$713

HK$791 total

includes taxes & fees

1 Nov - 2 Nov

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A hotel room with a sectional sofa, a bed, a desk, and a large window.

A large sports complex with multiple fields and tall light poles.

A modern building with a glass facade and a brick base, featuring a prominent entrance with a flag.

13. Comfort Suites Greenville Airport

Greenville

Ryan

HK$697

HK$790 total

includes taxes & fees

1 Nov - 2 Nov

A bar area with multiple hanging decorative lights, a counter with bar stools, and a seating area with chairs.

A banquet hall with round tables set for dining, large windows, and a stage with curtains.

A well-furnished living room with a chandelier, wooden furniture, and a view through a window.

14. Greenville Marriott

Greenville

John

HK$957

HK$1,085 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

15. Best Western Spartanburg Northwest

Spartanburg

Muhammad Awais

HK$727

HK$823 total

includes taxes & fees

1 Nov - 2 Nov

A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

A modern living room with a fireplace, seating area, and a bar with shelves of bottles.

16. Hotel Hartness

Greenville

Kodjo

HK$1,309

HK$1,742 total

includes taxes & fees

25 Oct - 26 Oct

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A pool area with lounge chairs and a sign for Best Western Plus.

17. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Stephanie

HK$596

HK$656 total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

18. Drury Inn & Suites Greenville

Greenville

Gohan

HK$902

HK$993 total

includes taxes & fees

1 Nov - 2 Nov

A modern restaurant with a brick wall, wooden ceiling beams, and a central seating area with tables and chairs.

A hallway with a wooden wall, a large abstract sculpture, and patterned flooring.

A snack and treat section with shelves stocked with various snacks, a chalkboard sign, and beverage dispensers.

An outdoor patio with a fire pit, seating area, and a TV.

19. Hampton Inn Greer Greenville, SC

Greer

Morgan

HK$1,130

HK$1,232 total

includes taxes & fees

11 Oct - 12 Oct

A modern lobby with a fireplace, comfortable seating, and a flat-screen TV.

An outdoor seating area with wicker furniture and red cushions, surrounded by a stone fire pit.

A modern lobby with a large screen displaying a cityscape, a dark wooden reception desk, and a tall vase with branches.

A modern hotel lobby with a bar area, seating arrangements, and a visible menu board.

20. Courtyard Greenville-Spartanburg by Marriott

Greer

Evan

HK$827

HK$937 total

includes taxes & fees

25 Oct - 26 Oct

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Holiday Rentals in Upstate South Carolina

Aparthotel

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

stayAPT Suites Greenville-Haywood Mall

Greenville

"Everything was great"

Aparthotel

A modern building with outdoor seating and a garden.

A modern living room with a sofa, coffee table, and dining table. There is a TV mounted on the wall, a coffee machine, and a bookshelf.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

A row of modern, two-story buildings with a covered patio area.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A wooden interior with a table, chair, and a hanging lantern.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"Me and my family had a great time"

Cabin

A swimming pool with lounge chairs and a covered area with tables and chairs.

A spacious living room with a dark leather sofa, a wooden coffee table, and a dining area with a table and chairs. Large windows provide natural light and views of the outdoors.

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a microwave.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cottage

A living room with a sofa, a dining table, chairs, a kitchen area, and a view through large windows.

A two-story house with a front porch, a small garden, and a wooden fence.

A blue house with a wooden deck, a red door, and a fenced backyard with a small garden.

A modern kitchen with a built-in oven, a coffee maker, and a small dining area with two chairs and a table.

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer

"Nice place en Greenville area "

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A modern kitchen with white cabinets, a stainless steel refrigerator, and a bar area with white stools.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Excellent location for our trip. Very clean, had everything we needed."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

A rustic cabin with a porch, wooden steps, and a picnic table.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A kitchen with a wooden countertop, a sink, a coffee maker, a toaster, and a window with a view of trees.

A dining area with a wooden table set for two, a blue chair, a small table with a lamp, and a kitchen in the background.

A bed with a white quilted cover, flanked by two wall-mounted nightstands with lamps.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

A dining area with a wooden table and grey upholstered chairs, a large mirror, and a painting on the wall.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A living room with a sofa, coffee table, and a dining area with chairs and a table.

A bedroom with a bed, bedside tables, a round mirror, and a ceiling fan.

A covered porch with wicker furniture, a round table with a bowl and a cup, and a view of a lush garden.

A living room with a fireplace, a round wooden table with chairs, a sofa, and a television.

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Greer

"Very cute home close to everything. Super clean and spacious. Well furnished."

Cottage

A house with a grey siding exterior, a white front door, and a window with a white frame.

A bedroom with a wooden bed, a dresser, a mirror, a window with blinds, and a door leading to a bathroom.

A living room with a brown sofa, a wooden coffee table, a fireplace, a television mounted above the fireplace, and a window with blinds.

A living room with a striped sofa, a patterned armchair, and a dark sofa with a floral pillow. There is a wooden coffee table with a book and a plant. A lamp is on a side table next to the sofa.

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Greenville

"Amazing place. Great host. "

Apartment

A large house with a spacious driveway and a pond in the background.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

A spacious living room with a high ceiling, a large leather sofa, a flat-screen TV, and a wooden coffee table.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

A backyard with a gazebo, a fire pit, and a covered seating area.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Cottage

A bedroom with a wooden bed, a nightstand, a chair, and a view of the outside through a window.

A modern kitchen with stainless steel appliances, white cabinetry, and a central island.

A covered deck with wooden flooring, outdoor furniture, and a barbecue grill.

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Seneca

"The best, perfect "

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland with a visit to Fred W. Symmes Chapel. Wander the lakeside and forests in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Comfort Inn Greenville - Haywood Mall

10/10 Excellent

"I was relocated to this property and it was better than the original property I booked with! I enjoyed my stay"

Embassy Suites Greenville Golf Resort & Conference Center

8/10 Good

"I have stayed at this embassy suites several times it's my go to if can't find a suitable hotel downtown Greenville. The hotel always accommodating and a short drive to downtown Greenville. (Great breakfast omelettes)"

Hotel Hartness

10/10 Excellent

"One of my favorite hotels so far. Beautiful grounds and well-appointed rooms. Excellent service. Great trails, beautiful location."

Clemson University's James F. Martin Inn

10/10 Excellent

"Love this place… great accommodations!"

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"The front desk staff was amazing. Very helpful. Genuinely concerned that we were ok with our accessible room. Very clean and well maintained operation. Good breakfast."

Hyatt Place Greenville Downtown

10/10 Excellent

"Hotel was in a great location. We were able to walk everywhere. The staff were all very friendly and helpful when we asked for restaurant recommendations."

Hampton Inn & Suites Greenville-Downtown-RiverPlace

10/10 Excellent

"😃"

Hilton Greenville

10/10 Excellent

"Room was clean and comfortable. Restaurant was surprisingly good. Staff were friendly and efficient."

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"Fantastic in every way!"

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

HK$560

HK$616 total

1 Nov - 2 Nov

includes taxes & fees

8.4/10 Very good! (1,007 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

HK$596

HK$656 total

18 Oct - 19 Oct

includes taxes & fees

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

HK$671

HK$762 total

11 Oct - 12 Oct

includes taxes & fees

8.2/10 Very good! (1,009 reviews)

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

HK$827

HK$918 total

8 Oct - 9 Oct

includes taxes & fees

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC

HK$840

HK$933 total

18 Oct - 19 Oct

includes taxes & fees

8.4/10 Very good! (1,008 reviews)

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC

HK$828

HK$1,030 total

9 Oct - 10 Oct

includes taxes & fees

Hotels in Upstate South Carolina with star-rating

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Things to do in Upstate South Carolina

Upstate South Carolina hotels from HK$489

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Upstate South Carolina hotels

1. Tru by Hilton Spartanburg

2. Hilton Garden Inn Spartanburg

3. AC Hotel by Marriott Spartanburg

4. Best Western Spartanburg I-26

5. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

6. Home2 Suites by Hilton Duncan

7. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

8. Embassy Suites Greenville Golf Resort & Conference Center

9. Hampton Inn & Suites Greenville Airport, SC

10. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

11. Four Points by Sheraton Spartanburg

12. Comfort Suites At WestGate Mall

13. Comfort Suites Greenville Airport

14. Greenville Marriott

15. Best Western Spartanburg Northwest

16. Hotel Hartness

17. Best Western Plus Greenville I-385 Inn & Suites

18. Drury Inn & Suites Greenville

19. Hampton Inn Greer Greenville, SC

20. Courtyard Greenville-Spartanburg by Marriott

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

The Station by Compo Hotels

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Carolina Camp Cedar

Greer Guest House < 1 Mi to Park & Downtown Area!

Mint House Greenville Downtown by Kasa

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Claires Cottage ~ 4 Mi to Downtown Greenville!

Families Welcome, Fenced Yard: Inviting Greer Home

1 Mi to Downtown Greer: Family Home w/ Gazebo!

Cozy Greenville Bungalow ~ 2 Mi to Downtown!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Home w/ Lake Keowee Access: Sleeps 7, Coffee Bar

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

Fred W. Symmes Chapel

Bon Secours Wellness Arena

Memorial Stadium

BMW Performance Center

Greenville Convention Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Comfort Inn Greenville - Haywood Mall

Embassy Suites Greenville Golf Resort & Conference Center

Hotel Hartness

Clemson University's James F. Martin Inn

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Hyatt Place Greenville Downtown

Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hilton Greenville

Grand Bohemian Lodge Greenville, Autograph Collection

More cheap stays in Upstate South Carolina

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Best Western Plus Clemson Hotel & Conference Center

Comfort Inn & Suites Clemson - University Area

Lakeside Lodge Clemson

Hotels in Upstate South Carolina with star-rating

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