Upstate South Carolina hotels from HK$565
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Pet friendly
Apartment
Apart hotel
Cabin
Condo
Family friendly
Chalet
Cottage
Check prices for these dates
Tonight
19 Sept - 20 SeptTomorrow
20 Sept - 21 SeptNext weekend
25 Sept - 27 SeptIn two weeks
2 Oct - 4 OctOur top choices for Upstate South Carolina hotels
1. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
Fairfield Inn & Suites by Marriott Greenville Spartanburg/DuncanDuncan
Joseph
HK$934
HK$1,050 total
includes taxes & fees
20 Sept - 21 Sept
2. Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
Teresa
HK$1,130
HK$1,231 total
includes taxes & fees
20 Sept - 21 Sept
3. Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
Travis
HK$840
HK$933 total
includes taxes & fees
4 Oct - 5 Oct
4. Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
Jeremy
HK$830
HK$921 total
includes taxes & fees
4 Oct - 5 Oct
5. Best Western Spartanburg I-26
Best Western Spartanburg I-26Spartanburg
Catherine
HK$727
HK$807 total
includes taxes & fees
4 Oct - 5 Oct
6. AC Hotel by Marriott Spartanburg
AC Hotel by Marriott SpartanburgSpartanburg
Willow
HK$1,248
HK$1,385 total
includes taxes & fees
20 Sept - 21 Sept
7. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHGSpartanburg
Michael
HK$777
HK$862 total
includes taxes & fees
18 Oct - 19 Oct
8. Hilton Garden Inn Spartanburg
Hilton Garden Inn SpartanburgSpartanburg
Stan
HK$1,062
HK$1,178 total
includes taxes & fees
11 Oct - 12 Oct
9. Comfort Suites Greenville Airport
Comfort Suites Greenville AirportGreenville
Ryan
HK$730
HK$827 total
includes taxes & fees
18 Oct - 19 Oct
10. Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
Savannah
HK$715
HK$794 total
includes taxes & fees
18 Oct - 19 Oct
11. Home2 Suites by Hilton Duncan
Home2 Suites by Hilton DuncanDuncan
Lilia
HK$926
HK$1,028 total
includes taxes & fees
15 Oct - 16 Oct
12. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
Sandy
HK$804
HK$911 total
includes taxes & fees
27 Sept - 28 Sept
13. Hampton Inn & Suites Greenville/Spartanburg I-85, SC
Hampton Inn & Suites Greenville/Spartanburg I-85, SCDuncan
Kathy
HK$862
HK$957 total
includes taxes & fees
4 Oct - 5 Oct
14. Hampton Inn & Suites Greenville Airport, SC
Hampton Inn & Suites Greenville Airport, SCGreenville
Marcella
HK$822
HK$931 total
includes taxes & fees
27 Sept - 28 Sept
15. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
Ryan
HK$596
HK$656 total
includes taxes & fees
4 Oct - 5 Oct
16. Hotel Hartness
Hotel HartnessGreenville
Cornelius
HK$1,194
HK$1,612 total
includes taxes & fees
4 Oct - 5 Oct
17. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
Michael
HK$777
HK$862 total
includes taxes & fees
18 Oct - 19 Oct
18. Courtyard by Marriott Greenville Mauldin
Courtyard by Marriott Greenville MauldinGreenville
Leticia
HK$934
HK$1,027 total
includes taxes & fees
27 Sept - 28 Sept
19. Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
Leslie
HK$787
HK$884 total
includes taxes & fees
27 Sept - 28 Sept
20. Courtyard Greenville-Spartanburg by Marriott
Courtyard Greenville-Spartanburg by MarriottGreer
Susan
HK$760
HK$861 total
includes taxes & fees
27 Sept - 28 Sept
Holiday Rentals in Upstate South Carolina
Aparthotel
Landing Apartments - Lyman
Landing Apartments - LymanLyman
"Great room that was nice and clean. Smooth check-in."
Cabin
Carolina Camp Cedar
Carolina Camp CedarPickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Aparthotel
stayAPT Suites Greenville-Haywood Mall
stayAPT Suites Greenville-Haywood MallGreenville
"I was there for work and I was close to everything"
Cabin
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
"Me and my family had a great time"
Cottage
Greer Guest House < 1 Mi to Park & Downtown Area!
Greer Guest House < 1 Mi to Park & Downtown Area!Greer
"Nice place en Greenville area "
Aparthotel
The Station by Compo Hotels
The Station by Compo HotelsTravelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
Cottage
Clemson Memorabilia House
Clemson Memorabilia HouseClemson
"We enjoyed our stay, it was the perfect size for our family of four. "
Mobile Home
Carolina Landing RV Resort - Caravan Park
Carolina Landing RV Resort - Caravan ParkFair Play
"Very nice stay with friendly staff"
Apartment
Mint House Greenville Downtown by Kasa
Mint House Greenville Downtown by KasaGreenville Downtown
"The unit was very clean, and I stay here whenever I'm in Greenville."
Apartment
Landing Apartments Greer - Sugar Creek
Landing Apartments Greer - Sugar CreekGreer
"The apartment was clean. Excellent value for stay. Amenities were great. Will book again!"
Cottage
1 Mi to Downtown Greer: Family Home w/ Gazebo!
1 Mi to Downtown Greer: Family Home w/ Gazebo!Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
Cottage
Families Welcome, Fenced Yard: Inviting Greer Home
Families Welcome, Fenced Yard: Inviting Greer HomeGreer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Cottage
< 3 Mi to Dtwn: Modern Cottage in Greenville!
< 3 Mi to Dtwn: Modern Cottage in Greenville!Greenville
Cottage
Cozy Greenville Bungalow ~ 2 Mi to Downtown!
Cozy Greenville Bungalow ~ 2 Mi to Downtown!Greenville
"Amazing place. Great host. "
Cottage
Greenwood Getaway w/ Furnished Patio & Lake View
Greenwood Getaway w/ Furnished Patio & Lake ViewGreenwood
"Wonderful stay and would definitely stay again! Reasonable price for the luxury place with everything that you could ask for in a rental. Close to restaurants and bars if that is your thing and right near the lake with beautiful views!! We loved our stay!"
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
BMW Performance Center
9.0/10 (90 reviews)
You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Heritage Park and CCNB Amphitheatre.
See all hotels in Upstate South Carolina
Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews
Hotel Hartness
10/10 Excellent
"The hotel is gorgeous and I got in on the float mediation which was amazing! Really enjoyed my stay!"
Hyatt Place Greenville/Haywood
8/10 Good
"The property was being updated (lobby only) but it wasn’t a major issue. The amount of people in the parking lot and sitting in vehicles was a little alarming but we didn’t have any issues. The room was great. Clean, spacious, and had everything that we needed."
Best Western Spartanburg I-26
10/10 Excellent
"Bathtubs very slippery. A fall hazard."
Lakeside Lodge Clemson
10/10 Excellent
"Great size rooms, very clean and well decorated!"
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
"I definitely recommend the place, and for sure I'll stay in the future"
Mint House Greenville Downtown by Kasa
8/10 Good
"Pretty standard hotel room for a higher price. Balcony is a joke. 😂"
Hyatt Place Greenville Downtown
10/10 Excellent
"Great place."
Comfort Inn Greenville - Haywood Mall
10/10 Excellent
"Thought breakfast was good staff helpful when I goofed up stay request and they added the extra day Room clean and organized"
Grand Bohemian Lodge Greenville, Autograph Collection
8/10 Good
"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."
More cheap stays in Upstate South Carolina
WoodSpring Suites Spartanburg - Duncan
255 Frontage Rd. Duncan SC
HK$502
HK$565 total
20 Sept - 21 Sept
includes taxes & fees
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
HK$596
HK$656 total
4 Oct - 5 Oct
includes taxes & fees
Comfort Inn Greenville - Haywood Mall
246 Congaree Road Greenville SC
HK$640
HK$727 total
4 Oct - 5 Oct
includes taxes & fees
8.2/10 Very good! (1,004 reviews)
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
HK$794
HK$881 total
21 Sept - 22 Sept
includes taxes & fees
Comfort Inn & Suites Clemson - University Area
1305 Tiger Blvd Clemson SC
HK$854
HK$948 total
18 Oct - 19 Oct
includes taxes & fees
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
HK$855
HK$1,061 total
20 Sept - 21 Sept
includes taxes & fees
9/10 Wonderful! (1,003 reviews)
Hotels in Upstate South Carolina with star-rating
4 Star Hotels
33 properties
3 Star Hotels
197 properties
2 Star Hotels
136 properties
Explore a world of travel with Expedia
- Hotels near Frankie's Fun Park
- Hotels near NewSpring Church
- Hotels near Greenville County Museum of Art
- Hotels near Paris Mountain State Park
- 5 Star Hotels in Gramling
- Bar Hotel Hotels in Clinton
- Apartments in Fountain Inn
- Cabin Rentals in Greer
- Ninety Six Hotels
- Cabin Rentals in Una
- Hotels near Discovery Island Water Park
- Apartments in Duncan
- Hotels near Greenwood Community Theatre
- Hotels near BMW Performance Center
- B&B in Woodruff
- Hotels near Greenwood County
- Motel 6 Hotels in Greer
- Hotels near Carolina Honey Bee Company
- Union Hotels
- Cabin Rentals in Boiling Springs
- Family Hotel Hotels in Duncan
- Hotels near Eugene Stone Soccer Stadium
- B&B in Boiling Springs
- Hotels near Anderson Mall
- Hotels near Greenville-Spartanburg Intl.
- B&B in Fountain Inn
- Red Roof Inn Hotels in Roebuck
- 3 Star Hotels in Laurens
- Belton Hotels
- Hotels near Spartanburg Downtown Memorial
- Rv Parks in Clinton
- B&B in Fingerville
- Motel 6 Hotels in Roebuck
- Spa Hotel Hotels in Duncan
- Taylors Hotels
- Anderson Hotels
- Cottages in Lyman
- Bar Hotel Hotels in Spartanburg
- Newberry Hotels
- Motels in Wellford
- 4 Star Hotels in Fingerville
- Blacksburg Hotels
- Guest Houses in Inman
- Greenwood Hotels
- Hotels near Cowpens National Battlefield
- Hotels near Pickens County
- Cabin Rentals in Upstate South Carolina
- Cabin Rentals in Wellford
- Hotels near Bob Jones University
- Pet-Friendly Hotel Hotels in Clinton
- Marriott Hotels & Resorts in Boiling Springs
- Carlisle Hotels
- Greenville Hotels
- West End Hotels
- Rv Parks in Inman
- B&B in Pauline
- Cabin Rentals in Clinton
- Cabin Rentals in Fountain Inn
- Roebuck Hotels
- Villas in Upstate South Carolina
- Hotels near Hollywild Animal Park
- Accor Hotels in Fingerville
- Rv Parks in Upstate South Carolina
- Greenville Downtown Hotels
- Flights from Roebuck
- Flights from Paris (PAR) to Greenville (GDC)
- Flights from Hong Kong (HKG) to Greenville (GDC)
- Flights from Lyman
- Flights from Los Angeles (LAX) to Greenville (GSP)
- Flights from Gray Court
- Flights from Sedalia (DMO) to Greenville (GSP)
- Flights to Upstate South Carolina
- Flights from Fort Myers (RSW) to Greenville (GMU)
- Flights from Hong Kong (HKG) to Greenville (GMU)
- Flights from Boiling Springs
- Flights from Lansing (LAN) to Greenville (GMU)
- Flights from Enoree
- Flights from Hong Kong (HKG) to Greenville (GSP)
- Flights from Mauldin
- Flights from Greenville Downtown
- Flights from Startex
- Visit Southern Shops
- Visit Greer
- Frankie's Fun Park
- Golden Lanes and Golden Skate
- Visit Spartanburg
- Bmw Zentrum
- Visit Startex
- Visit Enoree
- Visit Pauline
- Visit Upstate South Carolina
- Visit Fingerville
- Startex Holidays
- Visit Upstate South Carolina
- River Falls Golf Course
- Hub City Railroad Museum
- Visit Roebuck
- Tyger River Park
