Best Upstate South Carolina Hotels in 2026 from HK$505 - Fully Refundable Options

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Go beyond your typical stay in Upstate South Carolina

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Our top choices for Upstate South Carolina hotels

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

1. Best Western Spartanburg I-26

Spartanburg

Santhosh

HK$727

HK$807 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a bar area, seating, and large windows.

A restaurant with a central island seating area, multiple tables, and a large mural on the wall.

A bar area with a long counter, multiple stools, and shelves stocked with bottles.

An outdoor seating area with string lights, tables, and chairs at the Hilton Garden Inn.

2. Hilton Garden Inn Spartanburg

Spartanburg

Patrick

HK$900

HK$999 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel lobby with a long reception desk, bar area with stools, seating with patterned cushions, and a large window offering a view of greenery.

A Holiday Inn Express & Suites hotel with a covered entrance and multiple floors.

A hotel room with a kitchenette, two beds, a red sofa, and a dining area.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a framed artwork on the wall.

3. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

Deborah

HK$863

HK$958 total

includes taxes & fees

1 Nov - 2 Nov

A rooftop bar with seating, a bar area, and a view of the cityscape at dusk.

A spacious living area with a modern sofa, armchairs, a coffee table, and a dining area with chairs and a table.

A modern living room with a dark-colored sofa, armchairs, a coffee table, and a bookshelf filled with decorative items.

A swimming pool with steps leading up to a building entrance, surrounded by lounge chairs and umbrellas.

4. AC Hotel by Marriott Spartanburg

Spartanburg

Willow

HK$1,247

HK$1,384 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with sofas, a fire pit, and string lights.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

A modern interior with hanging chairs, tables, and a view of the parking lot.

A modern lounge area with seating arrangements, a large window offering a view of the outdoors, and contemporary lighting fixtures.

5. Tru by Hilton Spartanburg

Spartanburg

Volodymyr

HK$830

HK$921 total

includes taxes & fees

23 Nov - 24 Nov

A multi-level hotel lobby with a central atrium, multiple dining areas, and a reception desk.

A gym with treadmills, elliptical machines, and a pool visible through large windows.

A spacious lobby with modern furniture, a reception desk, and a decorative ceiling design.

6. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Caitlin

HK$759

HK$860 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with a fireplace, comfortable seating, and a large window.

A hotel lobby with a reception desk, a patterned carpet, and a large abstract wall art piece.

A modern hotel room with a large mirror, a sink, a microwave, and a compact kitchenette. There is a seating area with a chair and a sofa, and a large window with curtains.

A modern hotel lobby with a large seating area, a reception desk, and a view of the outdoors.

7. Hampton Inn & Suites Greenville Airport, SC

Greenville

Freda

HK$765

HK$867 total

includes taxes & fees

1 Nov - 2 Nov

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

8. Four Points by Sheraton Spartanburg

Spartanburg

Elaine

HK$840

HK$932 total

includes taxes & fees

8 Nov - 9 Nov

A modern living room with a fireplace, seating area, and a kitchen in the background.

A hotel room with a sofa, a bed, a desk, and a large window.

An aerial view of a sports complex with multiple sports fields, a large parking area, and a stadium.

A modern dining area with multiple tables and chairs, a large wall-mounted TV, and decorative wall art.

9. Comfort Suites Greenville Airport

Greenville

Azalia

HK$703

HK$797 total

includes taxes & fees

15 Nov - 16 Nov

A dining area with a wooden table, chairs, and a vase of white flowers.

A bar with multiple shelves of liquor bottles and glasses hanging above.

A large, two-story house with a symmetrical facade, large windows, and a central entrance.

A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

10. Hotel Hartness

Greenville

Nicole

HK$1,289

HK$1,719 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A modern lobby with blue sofas, a reception desk, and a glass coffee table.

A gym with treadmills, elliptical machines, and weight machines.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

11. Comfort Suites At WestGate Mall

Spartanburg

Willie

HK$689

HK$765 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

12. Spartanburg Marriott

Spartanburg

Daniel

HK$925

HK$1,027 total

includes taxes & fees

8 Nov - 9 Nov

A modern kitchen with a central island, bar stools, and pendant lighting.

A modern hotel lobby with a large TV, comfortable seating, and a view of the outdoors.

A hotel lobby with a reception desk, seating area, and large windows.

A modern hotel with a well-maintained lawn, brick pathway, and a row of white flowers.

13. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Spartanburg

Melinda

HK$847

HK$940 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a reception desk, green seating area, and multiple tables and chairs.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass facade and a well-lit exterior.

An outdoor patio area with brick walls, a fire pit, and several chairs and tables.

A modern lounge area with a green sofa, multiple tables, chairs, and a flat-screen TV.

14. Home2 Suites by Hilton Duncan

Duncan

Marina

HK$960

HK$1,066 total

includes taxes & fees

8 Nov - 9 Nov

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A reception area with a stone counter, a laptop, and a sign indicating a Chairman's Award.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

15. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Rubin

HK$596

HK$656 total

includes taxes & fees

1 Nov - 2 Nov

A hotel patio with outdoor seating, stone pillars, and a modern building in the background.

A modern kitchen with hanging light fixtures and bar seating.

A modern hotel room with a large desk, a comfortable sofa, and a bed.

A modern bar area with a central island, bar stools, and overhead lighting.

16. DoubleTree by Hilton Greenville Woodruff Road

Greenville

Jamie

HK$871

HK$987 total

includes taxes & fees

24 Nov - 25 Nov

A gym with treadmills, elliptical machines, and weight equipment.

A modern dining area with tables and chairs, a counter, and a seating bench.

A modern lobby with a sofa, chairs, a coffee table, artwork, a TV, and a potted plant.

17. Clarion Inn

Greenville

Johnny

HK$579

HK$637 total

includes taxes & fees

2 Nov - 3 Nov

A modern living room with a fireplace, two sofas, and a coffee table.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

18. Best Western Spartanburg Northwest

Spartanburg

Herbert

HK$693

HK$785 total

includes taxes & fees

22 Nov - 23 Nov

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a red accent wall.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

19. Drury Inn & Suites Greenville

Greenville

Jamie

HK$902

HK$992 total

includes taxes & fees

1 Nov - 2 Nov

An indoor swimming pool with multiple lanes, lounge chairs, and a clear view of the sky through large windows.

A hotel reception desk with a modern design, including a reception counter and a wall-mounted sign.

A hotel room with two beds, a desk, a chair, a TV, and a window.

A buffet with various food items, including omelets and baked goods, served in metal containers.

20. Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG

Duncan

Dawn

HK$729

HK$821 total

includes taxes & fees

26 Nov - 27 Nov

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Holiday Rentals in Upstate South Carolina

Aparthotel

A reception desk with a blue wall, a white counter, and dark cabinets. There is a vase with white flowers on the counter.

An outdoor patio with a stone barbecue grill and white Adirondack chairs.

A modern hotel with a sign reading "apt suites" and a parking lot with cars.

stayAPT Suites Greenville-Haywood Mall

Greenville

"The kitchen was nice and came with basic utensils which was helpful"

Apartment

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

A bedroom with a bed, bedside tables, a ceiling fan, and two windows with blinds.

A modern kitchen with granite countertops, double sinks, and a built-in dishwasher.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop. There are three white bar stools and two pendant lights.

Mint House Greenville Downtown by Kasa

Greenville Downtown

"Great location, convenient!"

Aparthotel

A modern building with outdoor seating and a garden.

A two-story house with a dark roof and siding, a front porch with four yellow chairs, and a well-maintained garden with shrubs and mulch.

A row of modern, two-story buildings with a covered patio area.

A modern kitchen with white cabinetry, a wooden dining table, and a black chair. There is a window with a view of greenery outside.

The Station by Compo Hotels

Travelers Rest

"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."

Cabin

A modern bedroom with a large bed, a ceiling fan, and a view of the outdoors through a window.

Carolina Camp Cedar

Pickens

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

Cabin

A wooden interior with a table, chair, and a hanging lantern.

A forested area with a cabin and a vehicle parked on a gravel path.

A wooden cabin bedroom with a bed, a desk, and a window overlooking a forest.

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

"My wife and I enjoyed our stay here. 10/10 experience."

Cottage

A living room with a blue sofa, a round coffee table with a vase of flowers, a patterned rug, and a chair. There are paintings on the walls and a window with curtains.

A bed with a white quilted cover, flanked by two wall-mounted nightstands with lamps.

A compact living space with a sofa, a small round table, a wicker chair, a kitchen area with a microwave and cabinets, and a TV mounted on the wall.

A dining area with a wooden table set for two, a blue chair, a small table with a lamp, and a kitchen in the background.

Claires Cottage ~ 4 Mi to Downtown Greenville!

Greenville

"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."

Cottage

A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

A bedroom with a bed, bedside tables, a nightstand, a wooden floor, a door, and a wall-mounted shelf.

A room with wooden sliding doors, a small black table with a potted plant, and a circular sign with the words "stay awhile".

A cozy living room with a dining table, sofas, and a chandelier.

Clemson Memorabilia House

Clemson

"We enjoyed our stay, it was the perfect size for our family of four. "

Mobile Home

A wooden dining table with green placemats, surrounded by chairs, in a cabin with large windows and wooden walls.

A cozy cabin interior with wooden walls, a loft bedroom, a dining area, and a sofa with cushions.

A cozy cabin interior with a wooden interior, a sofa, a television on a wooden stand, and a sign on the wall.

A wooden interior with a loft bed, a green chair, a wooden table, and a map on the wall.

Carolina Landing RV Resort - Caravan Park

Fair Play

"Very nice stay with friendly staff"

Cottage

A spacious living room with a dining area, a leather sofa, a TV, and artwork on the walls.

A bedroom with a bed, a chair, a nightstand, and a window with curtains.

A spacious living room with a brown leather sofa, a white shag rug, and a dining area with a table and chairs.

A white door with a brass knocker, a white bench, a potted plant, and a wicker basket outside a house with a brick foundation and a window with blinds.

Families Welcome, Fenced Yard: Inviting Greer Home

Greer

"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."

Cottage

A modern living room with a ceiling fan, a sofa, a chair, and a coffee table. There is a kitchen in the background with cabinets and a countertop.

A modern kitchen with white cabinets, stainless steel appliances, and a marble countertop.

A single-story house with a porch, a gravel driveway, and a well-maintained lawn.

A wooden bridge leading to a playground with green grass and trees.

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Greenville

Apartment

A large house with a spacious driveway and a pond in the background.

A modern kitchen with a central island, wooden cabinets, and a dining area with bar stools.

A kitchen with wooden cabinets, stainless steel appliances, a granite countertop, and a bar stool.

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Travelers Rest

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

Cottage

A white house with a sloped roof, surrounded by trees and a garden.

Clemson Game Day Cottage w/ Fire Pit

Clemson

Cottage

A modern kitchen with blue cabinets, a central island, and a spiral staircase leading to an upper level.

A two-story house with a covered porch, a small garden, and a view of a lake.

A two-story building with a covered porch, a flagpole, and a landscaped front yard.

A modern living room with a fireplace, a large TV, and a kitchen area with blue cabinets and a bar.

Greenwood Getaway w/ Furnished Patio & Lake View

Greenwood

"wonderful hosts, pet friendly, very clean"

Apartment

A modern kitchen with a central island, stainless steel appliances, and pendant lighting.

A two-story house with a front porch, a garage, and a small front yard with landscaping.

A covered patio area with outdoor seating, large windows, and a white exterior.

A modern kitchen with white cabinets, stainless steel appliances, and a central island with bar stools.

Steps to Lake Greenwood: Waterfront Gem w/ Patio

Greenwood

"Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon."

Apartment

A swimming pool with a view of a lake and docked boats.

A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.

A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

A multi-story hotel with a parking lot and a view of a lake.

Lake Keowee Condo: Resort Pools & Lake Access!

Salem

"Wow!! Absolutely beautiful property. Recent remodel with beautiful and very tasteful design. Amazingly clean, organized and tidy. We are from Denver and did not have exposure to Lake Keowee. The lake was beautiful with great walking trails on the property. Special and spectacular spot! We will definitely go back. This is a gated community. Super comfortable king beds and nice linens."

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Hotels recommended for families in Upstate South Carolina

Four Points by Sheraton Spartanburg

Spartanburg

HK$840

HK$932 total

includes taxes & fees

8 Nov - 9 Nov

Hilton Garden Inn Spartanburg

Spartanburg

HK$900

HK$999 total

includes taxes & fees

15 Nov - 16 Nov

Tru by Hilton Spartanburg

Spartanburg

HK$830

HK$921 total

includes taxes & fees

23 Nov - 24 Nov

A modern living room with a fireplace, a flat-screen TV, and a dining area with chairs and a table.

A hotel with a modern design, featuring a prominent entrance and a parking area.

A reception area with a wooden reception desk, a refrigerator stocked with beverages, and shelves with snacks.

Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Duncan

HK$902

HK$1,014 total

includes taxes & fees

23 Nov - 24 Nov

Best Western Plus Greenville I-385 Inn & Suites

Greenville

HK$596

HK$656 total

includes taxes & fees

1 Nov - 2 Nov

Comfort Suites At WestGate Mall

Spartanburg

HK$689

HK$765 total

includes taxes & fees

22 Nov - 23 Nov

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Spartanburg

HK$863

HK$958 total

includes taxes & fees

1 Nov - 2 Nov

A modern interior with a fireplace, seating, and a wooden accent wall.

A modern restaurant interior with high ceilings, pendant lighting, and a mix of seating options including booths and tables.

A hotel room with a flat-screen TV, a desk with a chair, and artwork on the wall.

A hotel room with a television, a sofa, a dining area with a table and chairs, a kitchen area with a sink, and a door.

Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Duncan

HK$780

HK$866 total

includes taxes & fees

8 Nov - 9 Nov

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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.

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A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.

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A bridge over a river with a waterfall, surrounded by trees and buildings.

The Peace Center

8.8/10 (940 reviews)

You can make plans for a show at The Peace Center during your trip to Greenville. Amble around this family-friendly area's riverfront or attend a sporting event.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.

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Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

See all hotels in Upstate South Carolina

A multi-tiered waterfall cascading over rocks in a forested area.

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"nice property. VERY CLEAN!! Breakfast was great and very convenient location"

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent

"The hotel’s staff were lovely and helpful."

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

10/10 Excellent

"Great value. The breakfast was a little lacking but they don't have a kitchen so not bad. Only thing was weird in this day that s modern hotel didn't have soap shampoo and conditioner dispensers in the shower but not a biggie. Definitely recommend for travelers on a budget"

Best Western Spartanburg I-26

8/10 Good

"The bed was very comfortable! Slept like a rock. The room was very cleanThe bathroom sink was located outside the bathroom, which I always hate. The breakfast had a little pancake maker and a yogurt machine. There were eggs and bacon. The eggs were cold though. Lots of juice options, toast and bagels. Would recommend"

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent

"To our pleasant surprise our two room, two bathroom, small kitchen suite was everything we could have asked for and more. Outstanding for the price. I've stayed in elegantly furnished hotels around the world. Our stay was all we could have asked for and more. Breakfast was a bonus. Staff was helpful The gym, small but adequate. All requests such as extra towels were accommodated. Parking was easy. We will certainly stay there again. Highly recommend! Ten stars out of ten."

Comfort Inn Greenville - Haywood Mall

8/10 Good

"."

Lakeside Lodge Clemson

10/10 Excellent

"Absolutely amazing! We can't wait to go back!! The bar staff was top notch!!"

Hilton Greenville

10/10 Excellent

"Location is great for getting to/from downtown area"

Clemson University's James F. Martin Inn

10/10 Excellent

"Love stay here when visiting my daughter at Clemson. Everyone is so nice and welcoming! Clean rooms and beautiful setting!"

More cheap stays in Upstate South Carolina

Greenville Inn and Suites

1314 S Pleasantburg Dr Greenville SC

HK$459

HK$505 total

27 Oct - 28 Oct

includes taxes & fees

Days Inn by Wyndham Greenville

60 Roper Mountain Rd Greenville SC

HK$473

HK$521 total

2 Nov - 3 Nov

includes taxes & fees

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

HK$560

HK$616 total

9 Nov - 10 Nov

includes taxes & fees

8.4/10 Very good! (1,008 reviews)

Baymont by Wyndham Greenwood

109 Enterprise Ct Greenwood SC

HK$587

HK$651 total

1 Nov - 2 Nov

includes taxes & fees

7.6/10 Good! (932 reviews)

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

HK$596

HK$656 total

1 Nov - 2 Nov

includes taxes & fees

9.2/10 Wonderful! (1,597 reviews)

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC

HK$671

HK$761 total

1 Nov - 2 Nov

includes taxes & fees

8.2/10 Very good! (1,006 reviews)

Hotels in Upstate South Carolina with star-rating

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Things to do in Upstate South Carolina

Upstate South Carolina hotels from HK$505

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Upstate South Carolina

Check prices for these dates

Filter by

Star rating

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Our top choices for Upstate South Carolina hotels

1. Best Western Spartanburg I-26

2. Hilton Garden Inn Spartanburg

3. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

4. AC Hotel by Marriott Spartanburg

5. Tru by Hilton Spartanburg

6. Embassy Suites Greenville Golf Resort & Conference Center

7. Hampton Inn & Suites Greenville Airport, SC

8. Four Points by Sheraton Spartanburg

9. Comfort Suites Greenville Airport

10. Hotel Hartness

11. Comfort Suites At WestGate Mall

12. Spartanburg Marriott

13. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

14. Home2 Suites by Hilton Duncan

15. Best Western Plus Greenville I-385 Inn & Suites

16. DoubleTree by Hilton Greenville Woodruff Road

17. Clarion Inn

18. Best Western Spartanburg Northwest

19. Drury Inn & Suites Greenville

20. Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG

Holiday Rentals in Upstate South Carolina

stayAPT Suites Greenville-Haywood Mall

Mint House Greenville Downtown by Kasa

The Station by Compo Hotels

Carolina Camp Cedar

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Claires Cottage ~ 4 Mi to Downtown Greenville!

Clemson Memorabilia House

Carolina Landing RV Resort - Caravan Park

Families Welcome, Fenced Yard: Inviting Greer Home

< 3 Mi to Dtwn: Modern Cottage in Greenville!

Serene Travelers Rest Apartment: 7 Mi to Downtown!

Clemson Game Day Cottage w/ Fire Pit

Greenwood Getaway w/ Furnished Patio & Lake View

Steps to Lake Greenwood: Waterfront Gem w/ Patio

Lake Keowee Condo: Resort Pools & Lake Access!

Hotels recommended for families in Upstate South Carolina

Four Points by Sheraton Spartanburg

Hilton Garden Inn Spartanburg

Tru by Hilton Spartanburg

Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Best Western Plus Greenville I-385 Inn & Suites

Comfort Suites At WestGate Mall

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Stay near popular Upstate South Carolina attractions

Clemson University

Falls Park on the Reedy

The Peace Center

Bon Secours Wellness Arena

Memorial Stadium

Greenville Convention Center

Haywood Mall

BMW Performance Center

Learn more about Upstate South Carolina

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Best Western Spartanburg I-26

Best Western Plus Greenville I-385 Inn & Suites

Comfort Inn Greenville - Haywood Mall

Lakeside Lodge Clemson

Hilton Greenville

Clemson University's James F. Martin Inn

More cheap stays in Upstate South Carolina

Greenville Inn and Suites

Days Inn by Wyndham Greenville

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Baymont by Wyndham Greenwood