Florence Piazza Santo Spirito Hotels

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Our top choices for Piazza Santo Spirito hotels

Oltrarno Splendid

Oltrarno Splendid
San Frediano, 0.2 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (97)
"It was Wonderful!!!"
United States
MARGARITA
The price is HK$1,206
HK$1,455 total
includes taxes & fees
19 Jan - 20 Jan 2026
Oltrarno Splendid

Soprarno Suites

Soprarno Suites
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (395)
"Beautiful rooms in ideal location and staff was friendly and helpful"
Canada
Dara
The price is HK$1,622
HK$1,912 total
includes taxes & fees
18 Jan - 19 Jan 2026
Soprarno Suites

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
The price is HK$1,376
HK$1,643 total
includes taxes & fees
18 Jan - 19 Jan 2026
AdAstra Suites

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
San Frediano, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (136)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (303)
"Great location and got fantastic service from the hotel. Room was very clean and comfortable. Definitely my first choice for staying in Firenze!"
Canada
LEI
The price is HK$7,006
HK$7,853 total
includes taxes & fees
24 Jan - 25 Jan 2026
Portrait Firenze - Lungarno Collection

Toscanelli Residenza D'epoca

Toscanelli Residenza D'epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (366)
"Great location with lots of sights and restaurants in walklng distance. "
Ireland
jennifer
The price is HK$721
HK$921 total
includes taxes & fees
19 Jan - 20 Jan 2026
Toscanelli Residenza D'epoca

Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (70)
"The whole experience was very pleasurable."
Canada
Dejan
Palazzo Martellini Residenza d'Epoca

Ottantotto Firenze

Ottantotto Firenze
San Frediano, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (169)
"Fabulous hotel , breakfast was amazing , great location "
United Kingdom
SAMANTHA
The price is HK$1,599
HK$1,887 total
includes taxes & fees
7 Jan - 8 Jan 2026
Ottantotto Firenze

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (372)
"Great property, plenty of space for my family. The location is great, we were able to walk everywhere including the train station. "
United States
Loren
The price is HK$1,183
HK$1,412 total
includes taxes & fees
11 Jan - 12 Jan 2026
Numa Florence Palazzo Belfiore

Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa
4.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1000)
"Great location and beautiful accommodation "
United States
Amy
Ponte Vecchio Suites & Spa

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (600)
"Excellent location! Truly a 5 star hotel ! Great service, breakfast, and service . Bedrooms were clean! Bathrooms were excellent!"
Canada
Pam
The price is HK$5,463
HK$6,156 total
includes taxes & fees
21 Jan - 22 Jan 2026
Hotel Lungarno - Lungarno Collection

Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (583)
"Incredible location and services!"
United States
William
Antica Torre di Via Tornabuoni 1

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (195)
"We had a wonderful stay. Service was impeccable. Wonderful breakfast is recommended. Great location, comfortable bed and plenty of hot water pressure."
United States
Peter
The price is HK$1,581
HK$1,867 total
includes taxes & fees
6 Jan - 7 Jan 2026
Leone Blu Suites | UNA Esperienze

Residenza Alessandra

Residenza Alessandra
San Giovanni, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (77)
"Lovely apartment in an excellent location. Linked to a hotel so helpful for check-in and daily cleaning."
United Kingdom
Rosa
Residenza Alessandra

Tornabuoni View

Tornabuoni View
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (310)
"Great Location and very friendly staff!"
United States
Aaron
Tornabuoni View

B & Beatrice

B & Beatrice
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (110)
"Good location Helpful staff"
United States
maryjo
The price is HK$751
HK$936 total
includes taxes & fees
11 Jan - 12 Jan 2026
B & Beatrice

Hotel Berchielli

Hotel Berchielli
4.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (1001)
"Staff were all very accommodating and friendly. Breakfast buffet great and location of hotel wonderful"
United States
Polly
The price is HK$1,902
HK$2,221 total
includes taxes & fees
22 Jan - 23 Jan 2026
Hotel Berchielli

Hotel Continentale - Lungarno Collection

Hotel Continentale - Lungarno Collection
4.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (728)
"Great location and a very clean hotel. Excellent staff. "
United States
Robert
The price is HK$2,727
HK$3,129 total
includes taxes & fees
21 Jan - 22 Jan 2026
Hotel Continentale - Lungarno Collection

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
San Frediano, 0.2 km from Piazza Santo Spirito
9.2 out of 10, Wonderful, (1073)
"Perfect stay"
United States
Juan P
Palazzo Mannaioni Suites

Palazzo Alfieri Residenza d’epoca

Palazzo Alfieri Residenza d’epoca
Duomo, 0.4 km from Piazza Santo Spirito
9.2 out of 10, Wonderful, (727)
"This was such a lovely hotel! It was in a great location with an incredible view. The staff was great and the breakfast was absolutely fantastic! I would highly recommend this hotel "
United States
Christine
The price is HK$1,578
HK$1,864 total
includes taxes & fees
25 Dec - 26 Dec
Palazzo Alfieri Residenza d’epoca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Piazza Santo Spirito Hotel Reviews

Hotels near other Piazza Santo Spirito attractions

Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, take a look at the 3052 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Piazza Santo Spirito?
Adjacent to Piazza Santo Spirito, Palazzo Alfieri Residenza d'epoca is one of the top choices for your stay based on our traveller data, and this residence offers a fitness centre and a rooftop terrace. Other good choices close by include 25hours Hotel Florence Piazza San Paolino and Solo Experience Hotel.
How many hotels will I find close to Piazza Santo Spirito?
Expedia has 3052 hotels and other accommodation options within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals near Piazza Santo Spirito.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Galileo Museum - Institute and Museum of the History of Science or Basilica of Santa Maria Novella. Via Maggio, Pitti Palace and Via de' Tornabuoni are landmarks that you won't want to miss. You can check out the local talent at Teatro Verdi, Visarno Arena and Teatro Comunale Florence.
How can I get to Piazza Santo Spirito?
With so many ways to get around, seeing all of the area near Piazza Santo Spirito is easy. Nearby metro stations include Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.

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