Preferred James Island hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for James Island Preferred
9.6 out of 10, Exceptional, (243 reviews)
"My wife and I loved it there. The staff is very kind and professional, the hotel was immaculate, and the restaurants were amazing."
Nathan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top James Island Hotel Reviews
Harborside at Charleston Harbor Resort and Marina
8/10 Good
Explore a world of travel with Expedia
- Vacation Homes in Morris Island
- Family Hotel Hotels in Charleston
- Cottages in Mount Pleasant
- Motels in Charleston
- Hotels near Marion Square
- Hotels near Shops at Charleston Place
- Cottages in Charleston
- Cottages in Sullivan's Island
- Pet-Friendly Hotel Hotels in Folly Beach
- Beach Hotel Hotels in Folly Beach
- 4 Star Hotels in Charleston Historic District
- West Ashley Hotels
- Hotels near Rainbow Row
- Hotels near South Carolina Aquarium
- Hotels near Charleston Harbor Marina
- Marriott Hotels & Resorts in Charleston
- Hotels near Shem Creek Park
- Guest Houses in Folly Beach
- Cabin Rentals in James Island
- B&B in Daniel Island
- Starwood Capital Hotels in French Quarter
- Apartments in Charleston
- Cheap Hotels in Charleston Historic District
- Charleston Historic District Hotels
- Hotels near Citadel Mall
- Downtown Charleston Hotels
- Charleston County Hotels
- Resorts in Sullivan's Island
- Boutique Hotel Hotels in Charleston Historic District
- Condo Rentals in Folly Beach
- Hotels near Waterfront Park
- 4 Star Hotels in Folly Beach
- Hotels near College of Charleston
- French Quarter Hotels
- Hotels near Music Farm
- Hotels near Splash Zone Waterpark
- Cottages in Folly Beach
- 5 Star Hotels in Folly Beach
- Hotels near Tolers Cove Marina
- Villas in Folly Beach
- Villas in Sullivan's Island
- Marriott Hotels & Resorts in Ridgeville
- All-Inclusive Hotel Hotels in French Quarter
- Cheap Hotels in Folly Beach
- Condo Rentals in Daniel Island
- Inns in James Island
- Hotels near Angel Oak Tree
- Resorts in James Island
- Pet-Friendly Hotel Hotels in Downtown Charleston
- Waters Edge Hotels
- Independent Hotels in Huger
- Spa Hotel Hotels in French Quarter
- Resorts in Mount Pleasant
- Hotel with Pool Hotels in West Ashley
- Spa Hotel Hotels in Charleston
- Mount Pleasant Hotels
- United States Coast Guard Historic District Hotels
- B&B in Johns Island
- Vacation Homes in Folly Beach
- Old Village Hotels
- Marriott Hotels & Resorts in Charleston Historic District
- 5 Star Hotels in Charleston
- Historic Hotel Hotels in Downtown Charleston
- Relais & Chateaux Hotels in Charleston
- Villas in Charleston
- 5 Star Hotels in Downtown Charleston
- Apartments in North Charleston
- Hotels near Pitt Street Bridge
- Hotels near Charleston City Market
- Guest Houses in Charleston
- Charleston Hotels
- Folly Beach Hotels
- Hotels near Patriots Point Links
- Historic Hotel Hotels in Charleston
- Flights from Waitangi (CHT) to Charleston (CHS)
- Flights to Charleston
- Flights from Hong Kong (HKG) to Charleston (CHS)
- Flights to Folly Beach
- Flights from London (LHR) to Charleston (CHS)
- Flights from Vancouver (YVR) to Charleston (CHS)
- Flights to Daniel Island
- Flights from Louisville (SDF) to Charleston (CHS)
- Flights from New York (JFK) to Charleston (CHS)
- Flights from Charlotte (CLT) to Charleston (CHS)