Drive on Holidays Car Hire in San Luis Obispo Wine Country
Photo by Anthony Hilario
Change your mindPenalty-free cancellation on many/select car hire
Treat yourselfMembers save 10% or more on over 1 million car hire
Shop smartCompare car suppliers to unlock big savings
Explore a world of travel with Expedia
- San Luis Obispo Hotels
- Romantic Hotel Hotels in San Luis Obispo
- Cabin Rentals in Avila Beach
- Motel 6 Hotels in Pismo Beach
- Spa Hotel Hotels in Avila Beach
- Villas in Pismo Beach
- Hotels near Avila Beach
- Boutique Hotel Hotels in Pismo Beach
- Hotels near Irish Hills Natural Reserve
- Best Western Hotels in Pismo Beach
- Hotels near Bishop Peak Trail
- Luxury Hotel Hotels in Avila Beach
- Hotel with Pool Hotels in San Luis Obispo
- Wyndham Extra Holidays Hotels in Edna Valley
- Hotels near North Beach Campground
- Hotels near Bubblegum Alley
- Casino Hotel Hotels in San Luis Obispo Wine Country
- Best Western Hotels in Arroyo Grande
- Best Western Hotels in Shell Beach
- 4 Star Hotels in Avila Beach
- Beach Hotel Hotels in Avila Beach
- Resorts in San Luis Obispo
- Apartments in San Luis Obispo
- Golf Hotel Hotels in San Luis Obispo
- Hotels near Kynsi Winery
- Hotels near Yang Sheng Foot Spa
- Family Hotel Hotels in San Luis Obispo
- Beach Hotel Hotels in Shell Beach
- Downtown San Luis Obispo Hotels
- 4 Star Hotels in Pismo Beach
- 3 Star Hotels in Pismo Beach
- Cheap Hotels in Grover Beach
- Beach Hotel Hotels in Los Osos
- 4 Star Hotels in San Luis Obispo
- Cheap Hotels in Pismo Beach
- Adventure Sport Hotel Hotels in Avila Beach
- Motels in Pismo Beach
- Pacifica Hotels in Los Osos
- Apartments in Edna
- B&B in Edna
- Hotels near The Spa at Dolphin Bay
- Independent Hotels in Edna Valley
- Hotels near California Polytechnic State University
- Pet-Friendly Hotel Hotels in Shell Beach
- Vacation Homes in Pismo Beach
- Lgbt Welcoming Hotel Hotels in San Luis Obispo
- Hotels near Dairy Creek Golf Course
- Cheap Hotels in San Luis Obispo
- Hilton Hotels in Edna
- Bar Hotel Hotels in Grover Beach
- Golf Hotel Hotels in Avila Beach
- Romantic Hotel Hotels in Los Osos
- Hotels near Sunset Drive-In Theatre
- B&B in San Luis Obispo
- Hotels near Pismo Beach Pier
- Hotels near Edna Valley Vineyard
- Pismo Beach Hotels
- Best Western Hotels in San Luis Obispo
- Wedding Hotels in Pismo Beach
- Rv Parks in San Luis Obispo
- Hotels near French Hospital Medical Center
- Avila Beach Hotels
- Boutique Hotel Hotels in San Luis Obispo
- Spa Hotel Hotels in San Luis Obispo
- Pet-Friendly Hotel Hotels in Avila Beach
- Shell Beach Hotels
- Casino Hotel Hotels in Arroyo Grande
- Motels in Grover Beach
- Grover Beach Hotels
- Cruise Inn Hotels in San Luis Obispo
- Green/Sustainable Hotels in San Luis Obispo
- Apartments in Edna Valley
- Winery Hotel Hotels in Avila Beach
- Luxury Hotel Hotels in Shell Beach
- Pacifica Hotels in Shell Beach
- Hotels near Cuesta College
- Cabin Rentals in San Luis Obispo
- Casino Hotel Hotels in Pismo Beach
- Beach Hotel Hotels in Pismo Beach
- Villas in Edna Valley
- Pet-Friendly Hotel Hotels in Pismo Beach
Heading to San Luis Obispo Wine Country? Explore San Luis Obispo Wine Country with Expedia's Travel Guides to find the best hotels, holiday packages, car hire deals and more!